Navigation Links
Growing fuel and medicine: Advancing biofuels and plant-produced therapeutics
Date:10/27/2008

, currently professor of integrative genomics at Princeton University. Prof. Botstein was referring to the elegant genetics possible in Bakers (or brewers) yeast in the 1980s, which made it an object of envy of scientists not working with yeast. Saccharomyces cerevisiae continues to push the limits of genomics and molecular genetic research because it is a simple, safe, fast, and facile eukaryotic organism. My laboratory uses S. cerevisiae to understand the fundamental mechanisms of fungal pathogenesis. For example: how fungi perceive secondary metabolites as cues and integrate these in a way that is beneficial to them. A clear understanding of this signaling pathway might allow us to disrupt microbial communication thereby interrupting the infection process. In addition we use genomic approaches to identify novel virulence factor as targets for antifungal drug development. Potential drug targets are subjected to high throughput screens to identify small molecules that inhibit their function. We also use the powerful genetic and genomic tools available in S. cerevisiae to understand the mode of action of ill-understood drugs at the molecular level. Such information can be used to increase efficacy or decrease side effects of drugs. Finally we are genetically modifying yeast to increase ethanol production from cellulosic feedstock.


'/>"/>

Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute
Source:Eurekalert

Page: 1 2 3 4 5 6

Related biology news :

1. Nanotech could make solar energy as easy and cheap as growing grass
2. Economical, nonpolluting solutions to greenhouse growing found
3. Research project aims to control sunlight, extend growing season and conserve energy
4. MRSA in hospital intensive care -- whats growing where?
5. A tall story: New research adds to growing body of knowledge of genetics of height
6. Genetic Engineering & Biotechnology News reports on growing use of cell-based assays
7. Establishing faster-growing, durable football fields
8. Growing use of nanomaterials spurs research to investigate possible downsides
9. Giant grass offers clues to growing corn in cooler climes, researchers report
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. Growing a garden of future environmental leaders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... improving the food intake, health and quality of life ... three projects at the University of Waterloo receiving close ... of Health Research (CIHR). , Professor Heather Keller, ... and a Schlegel research chair in nutrition and aging, ... many Canadians living in long-term care homes are poorly ...
(Date:8/21/2014)... finding that has implications for life in other extreme ... solar system, LSU Associate Professor of Biological Sciences Brent ... Foundation, or NSF, this week published a paper confirming ... lies 800 meters (2600 feet) beneath the surface of ... Given that more than 400 subglacial lakes and numerous ...
(Date:8/21/2014)... of the water window? It consists of radiations in ... absorbed by the water in biological tissues. New theoretical ... radiations within the water window. These could be the ... image of the biological samples or to be used ... the physical mechanism needed to efficiently generate the harmonic ...
Breaking Biology News(10 mins):Grants will fund landmark aging research at Waterloo 2800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 2800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 3800 meters beneath Antarctic ice sheet, subglacial lake holds viable microbial ecosystems 4Water window imaging opportunity 2
... New species are not just discovered in exotic localeseven ... new plants and animals. Academy scientists recently named a ... of fishes distantly related to sharks, from the coast ... species, the Eastern Pacific black ghostshark ( Hydrolagus melanophasma ...
... , , SEATTLE, Sept. ... leading provider of specialized reference laboratory and contract research services, today ... Terry M. Giles, providing for a $4 million loan (the "Loan") ... the Loan, on August 31, 2009, the Company also repurchased 2,391,906 ...
... , NEW YORK, Sept. 8 ... in its catalogue. , , ... http://www.reportlinker.com/p0131250/Carbon-Dioxide-Monitors.html , , This report ... of US$ by the following segments: End-tidal Carbon Dioxide (EtCO2) ...
Cached Biology News:New species of ghostshark from California and Baja California 2Pacific Biometrics Completes $4 Million Debt Financing 2Pacific Biometrics Completes $4 Million Debt Financing 3Pacific Biometrics Completes $4 Million Debt Financing 4Pacific Biometrics Completes $4 Million Debt Financing 5Reportlinker Adds Carbon Dioxide Monitors Report 2Reportlinker Adds Carbon Dioxide Monitors Report 3Reportlinker Adds Carbon Dioxide Monitors Report 4Reportlinker Adds Carbon Dioxide Monitors Report 5Reportlinker Adds Carbon Dioxide Monitors Report 6Reportlinker Adds Carbon Dioxide Monitors Report 7Reportlinker Adds Carbon Dioxide Monitors Report 8Reportlinker Adds Carbon Dioxide Monitors Report 9
(Date:8/21/2014)... DUBLIN, Ireland , August 21, 2014 ... and Markets ( http://www.researchandmarkets.com/research/3zh3q8/global_hormone ) has announced the ... Market 2014-2018"  report to their offering.  ... also known as hormone therapy, is a ... longer being produced by the body. This ...
(Date:8/21/2014)... 2014  Decision Resources Group finds that the ... and Mexico currently faces ... approved agents, the anticipated label extension of Boehringer ... of emerging biologics will substantially increase the competitiveness ... IL-5 inhibitors will introduce a new dynamic to the ...
(Date:8/21/2014)... Calif. , Aug. 21, 2014  Four-dimensional ... and behaviors based on external stimuli such as ... to have a disruptive effect in multiple industries.  ... the business landscape by printing objects ranging from ... and automotive sectors. Logo - ...
(Date:8/21/2014)... (PRWEB) August 21, 2014 ... has been recognized as one of the nation’s ... 5000 magazine for the 2nd consecutive year. Inc. ... 33rd annual Inc. 500|5000, an exclusive ranking of ... the most comprehensive look at the most important ...
Breaking Biology Technology:Global Hormone Replacement Therapy Market 2014-2018: Key Vendors are Actavis, Bayer, Merck & Co, Novartis and Novo Nordisk 2Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 2Asthma Agents Currently Face a Suboptimal Coverage Environment in Brazil and Mexico, and as the Treatment Armamentarium Expands, Competitiveness Will Further Intensify 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 2Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 3Frost & Sullivan: 4-D Printing to Usher in Age of Low-Labor, Fast-Paced Product Manufacturing 4SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3
... , ... ... ... ...
... ... ... ... ...
... , ... ... ... , ...
Cached Biology Technology:YM sees nimotuzumab license unaffected by civil claim against licensor 2YM sees nimotuzumab license unaffected by civil claim against licensor 3YM sees nimotuzumab license unaffected by civil claim against licensor 4YM sees nimotuzumab license unaffected by civil claim against licensor 5Concord Medical to Report Fourth Quarter and Fiscal Year 2009 Unaudited Financial Results on Thursday, March 18, 2010 2Concord Medical to Report Fourth Quarter and Fiscal Year 2009 Unaudited Financial Results on Thursday, March 18, 2010 3Concord Medical to Report Fourth Quarter and Fiscal Year 2009 Unaudited Financial Results on Thursday, March 18, 2010 4Concord Medical to Report Fourth Quarter and Fiscal Year 2009 Unaudited Financial Results on Thursday, March 18, 2010 5Concord Medical to Report Fourth Quarter and Fiscal Year 2009 Unaudited Financial Results on Thursday, March 18, 2010 6InterMune Announces Submission of MAA for Pirfenidone for the Treatment of Patients With IPF 2InterMune Announces Submission of MAA for Pirfenidone for the Treatment of Patients With IPF 3InterMune Announces Submission of MAA for Pirfenidone for the Treatment of Patients With IPF 4InterMune Announces Submission of MAA for Pirfenidone for the Treatment of Patients With IPF 5InterMune Announces Submission of MAA for Pirfenidone for the Treatment of Patients With IPF 6InterMune Announces Submission of MAA for Pirfenidone for the Treatment of Patients With IPF 7
... set the standard for sample concentration and drying. ... chamber uses a combination of centrifugal force, heat ... single run. , SC210A comes equipped with:, ... lasting chemical compatibility ...
... Acid Resistant SpeedVac Model SPD131DDA , Our ... SPD131DDA is designed to handle the rigors and ... slim design, digital display, dual independent timers, an ... chamber and vapor pathway. , , Adjustable ...
... Jouan RC Standard MB (For small quantities ... biology samples) of vacuum concentrator/centrifugal evaporator systems ... and biochemistry for rapid and safe concentration ... be expanded with pumps, different of cold ...
Monoclonal mouse antibody for immunihistology, clone AD12, Isotype IgG 1, purified, specific for rat pyruvatekinase type L, no cross-reactivities with other pyruvate kinase isoenzymes have been obser...
Biology Products: