Navigation Links
Growing corn to treat rare disease
Date:9/21/2012

lity.

Kermode says the success of the work underscores the power of multidisciplinary research that included contributions from SFU chemistry professor David Vocadlo, and from UBC Medical Genetics professor Lorne Clarke. It further underscores the importance of connections between SFU and Australia's Griffith University, through collaborative researchers Mark von Itzstein and Thomas Haselhorst.

"In 2005, we had the basis of our story worked out," says Kermode. "Taking it to the next level involved their precise analyses to determine the sugar residues on the therapeutic enzyme produced by the modified maize seeds.

"When we first looked at the sugar analysis data we were amazed at how well the 'mRNA-trafficking strategy' had worked, and the high fidelity of the process for controlling the sugar-processing of the therapeutic protein. This is critical as sugar processing influences the characteristics of a protein (enzyme) therapeutic, including its safety, quality, half-life in the bloodstream, and efficacy. The work could well extend to forming a platform for the production of other protein therapeutics."

Kermode also credits SFU research associate Xu He, the first author of the Nature Communications paper. Her funding sources included NSERC Strategic grants and a Michael Smith Foundation for Health Research Senior Scholar Award, and in related research, a Canadian Society for Mucopolysaccharide and Related Diseases grant.


'/>"/>

Contact: Allison Kermode
kermode@sfu.ca
778-782-3982
Simon Fraser University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Growing nitrous oxide levels explained
2. Growing risks from hatchery fish
3. What does a tree growing faster than its neighbor look like from outer space?
4. Learning from each other -- growing together
5. Ozone treated water v. lethal microbial material
6. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
7. Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
8. Genetic research develops tools for studying diseases, improving regenerative treatment
9. Step forward in research into new treatments for brain edema
10. Nanotherapy: Treating deadly brain tumors by delivering big radiation with tiny tools
11. New hope for treating Alzheimers Disease: A role for the FKBP52 protein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... , Dec. 23, 2014  Since its launch in December 2014, the ... eliminate the pain of trying to remember their usernames and ... fused to their smartphones. To assist people who have struggled ... company that created 1U and focuses on redefining identity, announced ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... "Micro Market Monitor: North America Perimeter Security Systems Market" ... The North American perimeter security market is ... to 2019. Although the U.S. market holds a larger share ...
(Date:12/17/2014)... NEW YORK , Dec. 15, 2014  HITLAB SM ... Practices (GCP) audit to confirm its adherence to current ... enables HITLAB to conduct regulated smart device and smart ... safety and research quality. "HITLAB is determined ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... may help to protect against some food allergies. Kefir, a ... health food, and is often used to wean babies, as ... in children under the age of three, with around 5-8% ... of the problematic food. , "Friendly" bacteria in kefir may ...
... in the event of a large-scale smallpox bioterrorist attack ... by researchers at Fred Hutchinson Cancer Research Center that ... , Instead, the current U.S. government policy of post-release ... workers and close contacts would be sufficient to thwart ...
... information is passed from parents to offspring via sperm or ... as yeast, the genes can be passed to the next ... occur in the genetic material after it has been duplicated ... mature gametes or spores. Near the end of the process, ...
Cached Biology News:Friendly bacteria in alcoholic milkshake could fight food allergies 2Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 2Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 3Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 4Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 5Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm 2
(Date:1/22/2015)... WI (PRWEB) January 22, 2015 Dr. Greg ... the 12th annual Scripps Natural Supplements Pre-Conference seminar on probiotics ... Conference is an annual continuing education conference for health care ... and included the topic of probiotics in health. Dr. Leyer ...
(Date:1/22/2015)... Diagenode, Inc., a leading global ... and complete solutions for epigenetics research, recently launched ... the need for manual processing. The new ChIPettor ... of histones or transcription factors and a semi-automated ...
(Date:1/22/2015)... , Jan. 22. 2015  Varian Medical Systems (NYSE: ... been honored for its commitment to sustainability with inclusion on ... is the highest ranked healthcare equipment company among the Corporate ... the World Economic Forum at Davos, Switzerland ...
(Date:12/25/2014)... The report “Service Quality Management and ... Provider Type - Global Advancements, Worldwide Forecasts & Analysis ... analysis and forecasting of revenues. , Browse 152 ... and in-depth TOC on “Service Quality Management (SQM) and ...
Breaking Biology Technology:Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Varian Honored Among World's 100 Most Sustainable Corporations 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4
... WASHINGTON - A delegation led by Governor Doyle and ... week for the biotechnology industrys leading conference with goals ... states research and university community and to let others ... to members of the group, the delegation met its ...
... get difficult, its the companies who dont panic, that will ... years ago, I was working on a project for the ... San Jose, California. I was arranging and conducting seminars for ... again going through a make or break situation with many ...
... WI - GE Medical Systems, a unit of General ... by the U.S. Food and Drug Administration to begin ... (MRI) system. The Signa EXCITE 3.0T combines the increased ... with the breadth of imaging capabilities found on premium ...
Cached Biology Technology:On site at BIO 2003 2On site at BIO 2003 3On site at BIO 2003 4On site at BIO 2003 5A Race without a Finish Line! 2GE Medical Systems Receives FDA Clearance for New MRI System 2
... duty stainless-steel shaker flask clips, purpose-designed to ... All clips are equipped with a ... also include a bottom retainer spring, and ... of expensive glassware. Clips include the ...
...
RABBIT ANTI HUMAN ALPHA-2-ANTIPLASMIN...
Anti-Tissue Trans-glutaminase (IgA) EIA Sample Size: 10 l...
Biology Products: