Genomics and Personalizing Medicine
Schatz discusses the subject of genetics and genomic medicine in a chapter entitled "Genomes for Individual Ability":
"The field of genetics exploded in the 20th century with the rise of molecular biology, the genome project, and the mapping of the human genome. Whereas genetics had previously been largely a descriptive discipline of genotypes and phenotypes, the sequencing of the genome has opened the world of protein processes and molecular expression.
The promise of the genome is captured by the P4 vision, personalized medicine, and the newly emerging discipline of Systems Biology. P4 stands for predictive, personalized, preventive, and participatory, characteristics that refer to human biology and the application of genome information to each individual. It is expected that knowledge of the genome will permit the prediction of health and disease. It will be possible to determine at the earliest stage that an individual has a risk for a later condition, or a threat to good health. The information will be personalized and suited for just that one individual whose character is contained in the genetic code. Because the genes being measured are finite fixed locations, genomic medicine is limited in its ability to measure variation of individuals within populations. Only data from the innermost rings of health determinants is included."
Healthcare Infrastructure: Health Systems for Individuals and Populations describes a new healthcare infrastructure that will gather personal health records from every individual and correlate each longitudinal record across whole populations. The book explains the problems of personal medicine and public health, then the solutions possible with information technology.
Bruce Schatz is professor and head of medical information science at Illinois and an affiliate in
|Contact: Nicholas Vasi|
Institute for Genomic Biology, University of Illinois at Urbana-Champaign