Navigation Links
Green is good
Date:4/9/2014

th of cultured muscle cells from humans.

"That result was important because we are looking for something that can help people," Adams says.

Their next step was to add tomatidine to the diet of mice. They found that healthy mice supplemented with tomatidine grew bigger muscles, became stronger and could exercise longer. And, most importantly, they found that tomatidine prevented and treated muscle atrophy.

Interestingly, although mice fed tomatidine had larger muscles, their overall body weight did not change due to a corresponding loss of fat, suggesting that the compound may also have potential for treating obesity.

Designing healthier foods

An attractive aspect of tomatidine is that it is a natural compound derived from tomatoes. It is produced when alpha-tomatine, which is found in tomato plants and in green tomatoes in particular, is digested in the gut.

"Green tomatoes are safe to eat in moderation. But we don't know how many green tomatoes a person would need to eat to get a dose of tomatidine similar to what we gave the mice. We also don't know if such a dose of tomatidine will be safe for people, or if it will have the same effect in people as it does in mice," Adams says. "We are working hard to answer these questions, hoping to find relatively simple ways that people can maintain muscle mass and function, or if necessary, regain it."

Adams and his team previously used this same research strategy to discover that ursolic acid, a compound from apple peels, promotes muscle growth.

"Tomatidine is significantly more potent than ursolic acid and appears to have a different mechanism of action. This is a step in the right direction," Adams says. "We are now very interested in the possibility that several food-based natural compounds such as tomatidine and ursolic acid might someday be combined into science-based supplements, or even simply incorporated into everyday foods to make
'/>"/>

Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-356-7124
University of Iowa Health Care
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. LAMIS -- a green chemistry alternative for laser spectroscopy
2. Green Oakley Cluster to double OSC computing power
3. UH makes Princeton Reviews Green List 3 years in a row
4. Gladstone scientist Warner C. Greene receives Washington University School of Medicine Alumni Award
5. Analysis of speed of Greenland glaciers gives new insight for rising sea level
6. A practical guide to green products and services
7. Old aerial photos supply new knowledge on glaciers in Greenland
8. Weizmann Institute solar technology to convert greenhouse gas into fuel
9. Steel-strength plastics -- and green, too!
10. Ancient global warming allowed greening of Antarctica
11. UCLAs Yi Tang receives Presidential Green Chemistry Challenge Award from EPA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... healthier for your neighbors than traditional cigarettes, but ... a new study from USC. , Scientists studying ... decrease in exposure to harmful particles, with close-to-zero ... to some harmful metals in second-hand e-cigarette smoke ... tobacco smoke contains high levels of polycyclic aromatic ...
(Date:8/28/2014)... A Mayo Clinic researcher and his collaborators have ... and enhance the process of re-engineering cells for biomedical ... network biology methods to aid stem cell engineering. Details ... are described in two back-to-back papers in the journal ... broad range of uses for all types of cell-based ...
(Date:8/28/2014)... FASEB MARC (Maximizing Access to Research Careers) Program ... Genetics Society of America,s 27th Annual Mouse Molecular ... 2014 in Pacific Grove, California. These awards ... post doctorates and scientists from underrepresented groups into ... to encourage the participation of young scientists at ...
Breaking Biology News(10 mins):Second-hand e-cig smoke compared to regular cigarette smoke 2New tool aids stem cell engineering for medical research 2
... is why mice engineered to have the abnormal protein ... the disease. Specifically, such mice are genetically altered to ... this protein that, when clipped by enzymes, produces the ... plaque that clogs the brain and kills brain cells. ...
... gene expression in the brain can differ significantly among ... study indicates that roughly 15 percent of Atlantic salmon ... their freshwater birthplaces to mature in oceans versus those ... , The researchers, at Harvard University, the University of ...
... pass on "traditions" to other members of their group, ... findings add to evidence that cultural learning is widespread ... Marineland in Niagara Falls in Ontario, Canada. An inventive ... and passed the strategy on to his tank-mates. The ...
Cached Biology News:Pinpointing a culprit molecule in Alzheimer's disease 2Divergent life history shapes gene expression in brains of salmon 2More animals join the learning circle 2
(Date:8/28/2014)... 28, 2014 Best Sanitizers, Inc., a ... food processing industry, is asking industry professionals to prepare ... of the E2 soap they’re currently using to the ... . Hand hygiene is critical to fighting cross-contamination ... environment. Six key criteria are identified to evaluate the ...
(Date:8/28/2014)... “This kit has an improved extraction efficiency and ... 150 ppb,” said Mark Tess, PhD, Mycotoxin Product Manager for ... owners and USDA-GIPSA inspection agencies that have a need to ... place in a matter of minutes with nothing but our ... feed and grain before accepting it, but they no longer ...
(Date:8/28/2014)... are important devices in spintronics, an electronic which ... electrons but also on their spin and the ... electric into magnetic signals and vice versa. Recently, ... the Institute of Physics at Johannes Gutenberg University ... Prague, and Japan, has for the first time ...
(Date:8/28/2014)... 28, 2014 The ability for organizations ... that will allow individuals to perform at the highest ... for employers looking to compete in this post–recession era. ... this trend, as the sector increasingly focuses on the ... which will have real results on the organization's development ...
Breaking Biology Technology:Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2A new, tunable device for spintronics 2A new, tunable device for spintronics 3Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3
... March 17 Spiral Biotech, an Advanced Instruments ... Plating System -- which delivers faster cycle ... that boost processing speed and efficiency in microbiology ... (ASM) General Meeting in May, 2009."The introduction of ...
... Cardiorobotics, Inc., a medical device ... a wide range of applications, including: medical, industrial, ... Dr. Samuel Straface in the position of President ... Straface has joined Cardiorobotics in this executive leadership ...
... Novavax, Inc. (Nasdaq: NVAX ) today announced that ... a press release to be issued after 8:00 a.m. Eastern ... investor conference call to discuss its financial results at 10:00 ... be hosted by Novavax President and Chief Executive Officer Dr. ...
Cached Biology Technology:Spiral Biotech to Introduce New Autoplate Spiral Plating System at ASM General Meeting in May 2Spiral Biotech to Introduce New Autoplate Spiral Plating System at ASM General Meeting in May 3Cardiorobotics Announces New CEO, PLSG Executive-in-Residence to Lead Company 2Cardiorobotics Announces New CEO, PLSG Executive-in-Residence to Lead Company 3Novavax Announces Release Date of 2008 Fourth Quarter Financial Results and Investor Conference Call 2Novavax Announces Release Date of 2008 Fourth Quarter Financial Results and Investor Conference Call 3
... Faster speeds, highest precision, more ... flexible concept: this is the definition of ... few years nucleic acid research has been ... capabilities required of PCR Systems. To ...
... genomics-based research with S. aureus, Sigma-Genosys has developed ... primers to amplify all open reading frames (ORFs) ... are included to amplify ORFs that are unique ... S. aureus. The ORFmer set contains primers to ...
... The Bio-Stack Twister II Microplate Handler ... automation solution for integrating BioTeks washers, ... with expandable microplate capacity, ultimate flexibility ... you are adding capacity to single ...
... Purification Kits enable rapid analytical to medium ... produced from appropriate vectors. Sufficient reagents are ... mg target protein under native or denaturing ... Agarose, which specifically retains STag fusion proteins. ...
Biology Products: