Navigation Links
'Green genes' in yeast may boost biofuel production by increasing stress tolerance
Date:12/15/2010

An effort to increase biofuel production has led scientists to discover genes in yeast that improve their tolerance to ethanol, allowing them to produce more ethanol from the same amount of nutrients. This study, published in the December 2010 issue of Genetics (http://www.genetics.org), shows how genetically altered yeast cells survive higher ethanol concentrations, addressing a bottleneck in the production of ethanol from cellulosic material (nonfood plant sources) in quantities that could make it economically competitive with fossil fuels.

"Our hope is that this research will take us closer to the goal of producing cheap, efficient, and environmentally friendly cellulosic ethanol," said Audrey P. Gasch, Ph.D., a researcher involved in the work and an Assistant Professor of Genetics from the University of Wisconsin-Madison. "At the same time, we've learned a lot about how cells respond to alcohol stress. So the project has been very productive from multiple angles."

To make this discovery, scientists turned to nature, studying how natural strains of the yeast Saccharomyces cerevisiae respond to ethanol treatment. They concluded that many wild strains of yeast respond to ethanol much differently than do traditional laboratory strains. When these wild yeast cells were treated with a low dose of ethanol, they mounted a response to become super-tolerant to high doses. By comparing and contrasting strains with different responses to ethanol, the researchers were able to quickly identify the specific genes responsible for the increased ethanol tolerance. They identified all genes in the yeast genome whose expression was affected when cells responded to ethanol. Comparing the responses of wild strains and a laboratory strain pointed the researchers to genes involved in high ethanol tolerance. The researchers were able to coax super ethanol tolerance in the laboratory strain by increasing expression of these genes.

"A lot of people think yeast is only useful to make beer, wine and bread," said Mark Johnston, Editor-in-Chief of the journal Genetics, "but it is also a key player in making 'green,' sustainable fuel sources part of the world's economy. By genetically priming these organisms to produce more ethanol, Gasch and her team have taken an important step away from fossil fuels."


'/>"/>

Contact: Tracey DePellegrin Connelly
td2p@andrew.cmu.edu
412-268-1812
Genetics Society of America
Source:Eurekalert

Related biology news :

1. MU scientists go green with gold, distribute environmentally friendly nanoparticles
2. Carbon dioxide scrubber captures greenhouse gases
3. Green coffee-growing practices buffer climate-change impacts
4. Greenhouse gas auction revenues can help cut Md. electric use significantly, says study
5. Green tea may delay onset of type 1 diabetes
6. Potent greenhouse gas more prevalent in atmosphere than previously assumed
7. What is really happening to the Greenland icecap?
8. A green future for scrap iron
9. Expert recommends town councils to design low-allergy impact green spaces
10. Parasite-resistant peppers green alternatives to chemical pesticides
11. MIT analysis shows how cap-and-trade plans can cut greenhouse emissions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... Lithuania , May 3, 2016  Neurotechnology, ... released the MegaMatcher Automated Biometric Identification System ... of large-scale multi-biometric projects. MegaMatcher ABIS can process ... accuracy using any combination of fingerprint, face or ... MegaMatcher SDK and MegaMatcher Accelerator ...
(Date:4/26/2016)... , April 27, 2016 ... "Global Multi-modal Biometrics Market 2016-2020"  report to their ... , The analysts forecast the global ... of 15.49% during the period 2016-2020.  ... of sectors such as the healthcare, BFSI, transportation, ...
(Date:4/14/2016)... 14, 2016 BioCatch ™, ... today announced the appointment of Eyal Goldwerger ... Goldwerger,s leadership appointment comes at a time ... the deployment of its platform at several of the ... which discerns unique cognitive and physiological factors, is a ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016 ... Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 Published ... the peer-reviewed journal from touchONCOLOGY, Andrew D ... cost of cancer care is placing an increasing ... of expensive biologic therapies. With the patents on ...
(Date:6/23/2016)... 22, 2016  Amgen (NASDAQ: AMGN ) ... QB3@953 life sciences incubator to accelerate the development ... laboratory space at QB3@953 was created to help high-potential ... for many early stage organizations - access to laboratory ... Amgen launched two "Amgen Golden Ticket" awards, providing each ...
(Date:6/22/2016)... , June 22, 2016   StockNewsNow.com , The ... Interview with Dr. Nader Pourhassan , President & ... focused on the clinical development and potential commercialization of ... HIV infection, according to the company,s website (see here: ... Tuesday, June 7 th , 2016, at the LD ...
(Date:6/22/2016)... DIEGO , June 22, 2016  Mesa ... has developed a testing platform designed specifically for ... formation of their scientific advisory board (SAB). Approved ... directors, the SAB is chartered to advise on ... disease assay platform. Led by Dr. Steve ...
Breaking Biology Technology: