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Greater seizure frequency seen in women with epilepsy during anovulatory cycle
Date:7/13/2011

ncy did not differ significantly for CPS, SPS, or for all seizures combined.

"Our results showed that GTCS frequency during anovulatory cycles correlate with proportional increases in estradiol-progesterone level ratios, suggesting sex hormones contribute to seizure incidence," concluded Dr. Herzog. "Efficacy results from the phase 3 clinical trial of a progesterone supplement that generated the data for the current study are forthcoming, and may provide a much needed treatment option to control seizures in women with epilepsy."

According to the National Institute of Neurological Disorders and Stroke (NINDS), tonic-clonic seizures, formerly known as grand mal seizures, are the most common type of generalized seizure and cause symptoms that include stiffening of the body, repeated jerking of the arms or legs, and loss of consciousness. The Epilepsy Foundation estimates that 200,000 new cases of epilepsy are diagnosed each year in the U.S., and roughly half of those are generalized onset seizures.


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Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

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