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Graphene nanoribbons for 'reading' DNA
Date:11/17/2013

ses, whereas in the materials used so far there was a 15 nm thickness." As a result, while previously it was not possible to individually analyze the passage of DNA bases through these "long" tunnels at a molecular scale , the new method is likely to provide a much higher precision. Eventually, it could be used for DNA sequencing.

However they are not there yet. In only 5 milliseconds, up to 50'000 DNA bases can pass through the pores. The electric output signal is not clear enough for "reading" the live sequence of the DNA strand passage. "However, the possibility of detecting the passage of DNA with graphene nanoribbons is a breakthrough as well as a significant opportunity", said Aleksandra Radenovic. She noted that, for example, the device is also able to detect the passage of other kinds of proteins and provide information on their size and/or shape.

This crucial step towards new methods of molecular analysis has received an ERC grant and is featured in an article published today in Nature Nanotechnology.


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Contact: Aleksandra Radenovic
aleksandra.radenovic@epfl.ch
41-216-937-371
Ecole Polytechnique Fdrale de Lausanne
Source:Eurekalert  

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