Navigation Links
Graphene nanoribbons for 'reading' DNA
Date:11/17/2013

If we wanted to count the number of people in a crowd, we could make on the fly estimates, very likely to be imprecise, or we could ask each person to pass through a turnstile. The latter resembles the model that EPFL researchers have used for creating a "DNA reader" that is able to detect the passage of individual DNA molecules through a tiny hole: a nanopore with integrated graphene transistor.

The DNA molecules are diluted in a solution containing ions and are driven by an electric field through a membrane with a nanopore. When the molecule goes through the orifice, it provokes a slight perturbation to the field, detectable not only by the modulations in ionic current but also by concomitant modulation in the graphene transistor current. Based on this information, it is possible to determine whether a DNA molecule has passed through the membrane or not.

This system is based on a method that has been known for over a dozen years. The original technique was not as reliable since it presented a number of shortcomings such as clogging pores and lack of precision, among others. "We thought that we would be able to solve these problems by creating a membrane as thin as possible while maintaining the orifice's strength", said Aleksandra Radenovic from the Laboratory of Nanoscale Biology at EPFL. Together with Floriano Traversi, postdoctoral student, and colleagues from the Laboratory of Nanoscale Electronics and Structures, she came across the material that turned out to be both the strongest and most resilient: graphene, which consists of a single layer of carbon molecules. The strips of graphene or nanoribbons used in the experiment were produced at EPFL, thanks to the work carried out at the Center for Micro Nanotechnology (CMI) and the Center for Electron Microscopy (CIME).

"Through an amazing coincidence, continued the researcher, the graphene layer's thickness measures 0.335 nm, which exactly fits the gap existing between two DNA ba
'/>"/>

Contact: Aleksandra Radenovic
aleksandra.radenovic@epfl.ch
41-216-937-371
Ecole Polytechnique Fdrale de Lausanne
Source:Eurekalert  

Page: 1 2

Related biology news :

1. High-resolution atomic imaging of specimens in liquid by TEM using graphene liquid cell
2. Using graphene, scientists develop a less toxic way to rust-proof steel
3. Graphene plasmonics beats the drug cheats
4. Researchers use graphene quantum dots to detect humidity and pressure
5. MindSpec launches online Autism Reading Room
6. New model of disease contagion ranks US airports in terms of their spreading influence
7. Flightless molecule may prevent cancer from spreading from 1 tissue to another
8. Frequent traveller: Dysentery-causing bacteria spreading from Europe to Australia
9. Brain-wave-reading robot might help stroke patients
10. New book on stereology by Mark West is essential reading for neurobiologists
11. Joint UT study: Reading food labels helps shoppers stay thinner
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Graphene nanoribbons for 'reading' DNA
(Date:9/12/2014)... an active role in the destruction and remodelling ... being an ,innocent bystander, as previously thought. , ... Lawler, Dr Ben Croker and colleagues from the ... while investigating the role of the protein SOCS3 ... was published in the journal Arthritis and ...
(Date:9/12/2014)... coccidiosis is a serious parasitic infection of young ... to diarrhoea and reduced nutritional intake. As the ... can result in increased mortality, the disease is ... farms., "The developing immune system of neonatal piglets ... the parasites. For this reason, an infection shortly ...
(Date:9/11/2014)... with autism often show a reduced frequency of ... in repetitive solitary behaviors. Autism has also been ... structure involved in processing emotions. Now Caltech researchers ... amygdala that control whether the animal engages in ... may have implications for understanding neural circuit dysfunctions ...
Breaking Biology News(10 mins):No innocent bystander: Cartilage contributes to arthritis 2Piglet health 2Piglet health 3Tipping the balance of behavior 2Tipping the balance of behavior 3
... the late 1800s, a flurry of fossil speculation across the ... Bone Wars. Drawn into the spectacle were two scientists ... acclaimed as the Father of Texas Geology, and naturalist Jacob ... Hill and Boll had supporting roles in the Bone ...
... to the amount of unhealthy foods they eat, but can ... new study in the Journal of Consumer Research . ... willpower and desire, consumers can,t rely entirely on willpower to ... will make them lose interest in food. One way is ...
... side-effects caused by the anti-parasitic drug quinine in the treatment ... The research, carried out by Nottingham scientists on the University,s ... in our levels of the amino acid, tryptophan, has a ... appears that the lower our levels of tryptophan the more ...
Cached Biology News:Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars 2Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars 3Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars 4Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars 5Eat dessert first? It might help you control your diet 2Diet could combat adverse side-effects of quinine 2Diet could combat adverse side-effects of quinine 3
(Date:9/11/2014)... 2014 The Registration Committee today ... now open for Pittcon 2015, the world’s largest ... event will be held March 8-12, 2015, at ... , The discounted registration fee of $175 ... 2/20/2015). This affordable price includes unlimited week-long access ...
(Date:9/11/2014)... September 11, 2014 ... production of its biocompatible, non-toxic and non-leaching antimicrobial Sanipolymers™. ... as one of the top tech startups of ... biomimetics to create antimicrobial plastics. Consumers are ... touch surfaces use hazardous substances. These substances or additives ...
(Date:9/11/2014)... (PRWEB) September 11, 2014 DuPont ... excited to announce that it has appointed ... two wholly owned subsidiaries, Essex Grain Products ... of Zemea® USP propanediol in the food and ... following USA eastern and mid-western states: Alabama, ...
(Date:9/10/2014)... 11, 2014 Daten ... der Jahresversammlung der Europäischen Gesellschaft für gynäkologische ... Tumorprofilierung als "Wendepunkt" für Onkologen. ... ein deutlich längeres Überleben nach der Profilierung ... peritonealem Krebs, denen Behandlungen verabreicht wurden, die ...
Breaking Biology Technology:Conferee Registration Opens for Pittcon 2015; Housing & Travel Open for Reservations 2World's First Biocompatible and Non-toxic Antibacterial Plastic 2DuPont Tate & Lyle Bio Products Appoints Skidmore Sales as Distributor for Zemea® USP 2DuPont Tate & Lyle Bio Products Appoints Skidmore Sales as Distributor for Zemea® USP 3Verbesserte Überlebensrate von Patientinnen mit Eierstockkrebs, die Behandlungen nach Anleitung durch komplette Tumorprofilierung erhalten 2Verbesserte Überlebensrate von Patientinnen mit Eierstockkrebs, die Behandlungen nach Anleitung durch komplette Tumorprofilierung erhalten 3Verbesserte Überlebensrate von Patientinnen mit Eierstockkrebs, die Behandlungen nach Anleitung durch komplette Tumorprofilierung erhalten 4Verbesserte Überlebensrate von Patientinnen mit Eierstockkrebs, die Behandlungen nach Anleitung durch komplette Tumorprofilierung erhalten 5
... Ocean energy company, BioPower Systems (BPS), today announced ... Hon. Michael O,Brien MP, has awarded the company conditional ... Pilot Demonstration Program. The funding will be ... company,s 250kW bioWAVE ocean wave energy system at a ...
... RSB Spine announced today that it received a revised ... an interbody implant with integrated fixation and an anterior ... for stand-alone interbody devices with integrated fixation.   The new ... new code for cervical interbody devices is OVE.   In ...
... 30, 2011  Nutra Pharma Corporation (OTCBB: NPHC), a biotechnology ... Human Immunodeficiency Virus (HIV), Adrenomyeloneuropathy (AMN) and Pain, announced ... publishing a mechanism study on the use of Alpha-Cobratoxin, ... pain. The paper was co-authored by Paul Reid, PhD ...
Cached Biology Technology:BioPower Systems Awarded $5 Million from Victorian Government 2BioPower Systems Awarded $5 Million from Victorian Government 3FDA Establishes New Product Codes for Interbody Devices With Integrated Fixation 2Nutra Pharma Announces Publication of a New Mechanism Study of Alpha-Cobratoxin in the Treatment of Pain 2Nutra Pharma Announces Publication of a New Mechanism Study of Alpha-Cobratoxin in the Treatment of Pain 3
ID clarifier: non-treated with lid...
... Series of systems provide fast and reliable scalable automation ... development laboratories. Staccato systems are available in three base ... Series. ... All Staccato Application ...
... provide fast and reliable automation for ... drug development laboratories. Staccato Custom Series ... providing solutions that are tailored to ... Systems are controlled with either Caliper's ...
... Use in any standard fixed-angle microcentrifuge ... g.,Spin- centrifuge tube filters consist ... a centrifuge tube. They filter by ... HPLC sample preparation, removal of cells ...
Biology Products: