Navigation Links
Grape skin extract may soon be answer to treating diabetes

DETROIT The diabetes rate in the United States nearly doubled in the past 10 years. Approximately 26 million Americans are now classified as diabetic, stressing an urgent need for safe and effective complementary strategies to enhance the existing conventional treatment for diabetes.

Preliminary studies by researchers at Wayne State University have demonstrated that grape skin extract (GSE) exerts a novel inhibitory activity on hyperglycemia and could be developed and used to aid in diabetes management. Recently funded by the National Center for Complementary and Alternative Medicine of the National Institutes of Health, this $2.1 million transitional study will provide insights into the novel inhibitory action of GSE on postprandial hyperglycemia and will also provide preclinical data in support of the biological effectiveness and safety of GSE and its components in potential prevention and treatment of type 2 diabetes.

"It is hopeful that our research may eventually lead to the successful development of a safe, targeted nutritional intervention to support diabetes prevention and treatment," said Kequan Zhou, Ph.D., assistant professor of food and nutrition science in the College of Liberal Arts and Sciences, and lead investigator on the grant. "Our study will provide important pre-clinical data regarding the anti-diabetic mechanisms, biological efficacy and safety of GSE that should facilitate eventual translation into future clinical studies to assess GSE and its components as a safe, low-cost and evidence-based nutritional intervention for diabetes."

Type 2 diabetes is the most common form of diabetes. With type 2 diabetes, the body does not produce enough insulin or the cells ignore the insulin. In addition, some groups have a higher risk for developing type 2 diabetes, including African Americans, Latinos, Native Americans, Asian Americans/Pacific Islanders, and the elderly.

"Type 2 diabetes is one of the major chronic diseases of modern societies," said Gloria Heppner, Ph.D., associate vice president for research at Wayne State University. "It threatens the health of a variety of populations, with growing numbers of young people being diagnosed with the disease every day. Dr. Zhou's study offers great hope for a potential treatment that is natural and without harmful side effects for the many people inflicted with type 2 diabetes."


Contact: Julie O'Connor
Wayne State University - Office of the Vice President for Research

Related biology news :

1. Eating grapes may help protect heart health in men with metabolic syndrome, new study suggests
2. NEIKER and INRA discover that BDA symptoms in grapevine leaves are a sign of esca
3. Selective grazing and aversion to olive and grape leaves achieved in goats and sheep
4. Compound in grapes, red wine could be key to fighting prostate cancer
5. A digital portrait for grapes indicates their ripeness
6. RIT scientists decode 3 bacterial strains common to grapevines and sugarcane
7. Even in same vineyard, different microbes may create variations in wine grapes
8. Grape intake may protect against metabolic syndrome-related organ damage
9. Study uncovers mechanism for how grapes reduce heart failure associated with hypertension
10. Grape consumption associated with healthier eating patterns in US children and adults
11. Geography has impact on grapevine moths success in French vineyards
Post Your Comments:
Related Image:
Grape skin extract may soon be answer to treating diabetes
(Date:11/16/2015)... Calif. , Nov 16, 2015  Synaptics ... of human interface solutions, today announced expansion of ... TouchView ™ touch controller and display driver ... revolution of smartphones. These new TDDI products add ... TD4100 (HD resolution), TD4302 (WQHD resolution), and TD4322 ...
(Date:11/10/2015)... 10, 2015  In this report, the ... of product, type, application, disease indication, and ... report are consumables, services, software. The type ... biomarkers, efficacy biomarkers, and validation biomarkers. The ... diagnostics development, drug discovery and development, personalized ...
(Date:11/2/2015)... 2, 2015  SRI International has been awarded a ... development services to the National Cancer Institute (NCI) PREVENT ... scientific expertise, modern testing and support facilities, and analytical ... and toxicology studies to evaluate potential cancer prevention drugs. ... PREVENT Cancer Drug Development Program is an NCI-supported pipeline ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... , Nov. 24, 2015  Asia-Pacific (APAC) holds ... organisation (CRO) market. The trend of outsourcing to ... margins but higher volume share for the region ... scale, however, margins in the CRO industry will ... Market ( ), finds that the ...
(Date:11/24/2015)... , Nov. 24, 2015 Cepheid (NASDAQ: ... be speaking at the following conference, and invited investors ... York, NY      Tuesday, December 1, 2015 at ... York, NY      Tuesday, December 1, 2015 at ... Healthcare Conference, New York, NY ...
(Date:11/24/2015)... 2015 /CNW/ - iCo Therapeutics ("iCo" or "the Company") ... for the quarter ended September 30, 2015. Amounts, ... and presented under International Financial Reporting Standards ("IFRS"). ... said Andrew Rae , President & CEO ... not only value enriching for this clinical program, ...
(Date:11/24/2015)... , ... November 24, 2015 , ... ... of the year and one of the premier annual events for pharmaceutical manufacturing: ... from 8–11 November 2015, where ISPE hosted the largest number of attendees in ...
Breaking Biology Technology: