Navigation Links
Grape intake may protect against metabolic syndrome-related organ damage
Date:4/22/2013

ANN ARBOR, MI - Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, according to research presented Monday at the Experimental Biology conference in Boston. Natural components found in grapes, known as polyphenols, are thought to be responsible for these beneficial effects.

The study, led by investigator E. Mitchell Seymour, Ph.D., of the University of Michigan Health System, studied the effects of a high fat, American-style diet both with added grapes and without grapes (the control diet) on the heart, liver, kidneys, and fat tissue in obesity-prone rats. The grapes a blend of red, green and black varieties were provided as a freeze-dried grape powder and integrated into the animals' diets for 90 days.

Specifically, the results showed that three months of a grape-enriched diet significantly reduced inflammatory markers throughout the body, but most significantly in the liver and in abdominal fat tissue. Consuming grapes also reduced liver, kidney and abdominal fat weight, compared with those consuming the control diet. Additionally, grape intake increased markers of antioxidant defense, particularly in the liver and kidneys.

Metabolic syndrome is a cluster of conditions that occur together increased blood pressure, a high blood sugar level, excess body fat around the waist or low HDL (the good cholesterol) and increased blood triglycerides significantly increasing the risk for heart disease, stroke and Type 2 diabetes. Intake of fruits and vegetables is thought to reduce these risks, and grapes have shown benefits in multiple studies. Metabolic syndrome is a major public health concern, and is on the rise in the U.S.

"Our study suggests that a grape-enriched diet may play a critical role in protecting against metabolic syndrome and the toll it takes on the body and its organs," said Seymour. "Both inflammation and oxidative stress play a role in cardiovascular disease progression and organ dysfunction in Type 2 diabetes. Grape intake impacted both of these components in several tissues which is a very promising finding."

This work extends and reinforces the findings of Seymour's previously published research which demonstrated that a grape-enriched diet reduced risk factors for heart disease and diabetes in obesity-prone rats.


'/>"/>

Contact: Justin Harris
juaha@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related biology news :

1. Even in same vineyard, different microbes may create variations in wine grapes
2. RIT scientists decode 3 bacterial strains common to grapevines and sugarcane
3. A digital portrait for grapes indicates their ripeness
4. Compound in grapes, red wine could be key to fighting prostate cancer
5. Selective grazing and aversion to olive and grape leaves achieved in goats and sheep
6. NEIKER and INRA discover that BDA symptoms in grapevine leaves are a sign of esca
7. Eating grapes may help protect heart health in men with metabolic syndrome, new study suggests
8. Rise in sodium intake in US over last decade despite health officials call for reduction
9. Excess vitamin E intake not a health concern
10. High-carb intake in infancy has lifelong effects, UB study finds
11. Kids consumption of sugared beverages linked to higher caloric intake of food
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted ... quarter of 2015 The gross margin was 49% (27) ... the operating margin was 40% (-13) Earnings per share ... operations was SEK 249.9 M (21.2) , Outlook   ... M. The operating margin for 2016 is estimated to ...
(Date:4/15/2016)... -- Research and Markets has announced the ...  report to their offering.  ,      ... gait biometrics market is expected to grow at ... Gait analysis generates multiple variables such ... compute factors that are not or cannot be ...
(Date:3/29/2016)... RATON, Florida , March 29, 2016 ... or the "Company") LegacyXChange "LEGX" and SelectaDNA/CSI Protect are ... DNA in ink used in a variety of writing ... theft. Buyers of originally created collectibles from athletes on ... through forensic analysis of the DNA. ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016   Boston Biomedical ... novel compounds designed to target cancer stemness pathways, ... been granted Orphan Drug Designation from the U.S. ... of gastric cancer, including gastroesophageal junction (GEJ) cancer. ... designed to inhibit cancer stemness pathways by targeting ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... YM (Yeast and Mold) microbial test has received AOAC Research Institute approval 061601. ... microbial tests introduced last year,” stated Bob Salter, Vice President of Regulatory and ...
(Date:6/23/2016)... ... June 23, 2016 , ... Supplyframe, the Industry Network for ... Design Lab . Located in Pasadena, Calif., the Design Lab’s mission is to ... are designed, built and brought to market. , The Design Lab is Supplyframe’s ...
(Date:6/23/2016)... BEACH, Calif. , June 23, 2016  Blueprint ... new biological discoveries to the medical community, has closed ... co-founder Matthew Nunez . "We have ... us with the capital we need to meet our ... will essentially provide us the runway to complete validation ...
Breaking Biology Technology: