Navigation Links
Grape intake may protect against metabolic syndrome-related organ damage
Date:4/22/2013

ANN ARBOR, MI - Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, according to research presented Monday at the Experimental Biology conference in Boston. Natural components found in grapes, known as polyphenols, are thought to be responsible for these beneficial effects.

The study, led by investigator E. Mitchell Seymour, Ph.D., of the University of Michigan Health System, studied the effects of a high fat, American-style diet both with added grapes and without grapes (the control diet) on the heart, liver, kidneys, and fat tissue in obesity-prone rats. The grapes a blend of red, green and black varieties were provided as a freeze-dried grape powder and integrated into the animals' diets for 90 days.

Specifically, the results showed that three months of a grape-enriched diet significantly reduced inflammatory markers throughout the body, but most significantly in the liver and in abdominal fat tissue. Consuming grapes also reduced liver, kidney and abdominal fat weight, compared with those consuming the control diet. Additionally, grape intake increased markers of antioxidant defense, particularly in the liver and kidneys.

Metabolic syndrome is a cluster of conditions that occur together increased blood pressure, a high blood sugar level, excess body fat around the waist or low HDL (the good cholesterol) and increased blood triglycerides significantly increasing the risk for heart disease, stroke and Type 2 diabetes. Intake of fruits and vegetables is thought to reduce these risks, and grapes have shown benefits in multiple studies. Metabolic syndrome is a major public health concern, and is on the rise in the U.S.

"Our study suggests that a grape-enriched diet may play a critical role in protecting against metabolic syndrome and the toll it takes on the body and its organs," said Seymour. "Both inflammation and oxidative stress play a role in cardiovascular disease progression and organ dysfunction in Type 2 diabetes. Grape intake impacted both of these components in several tissues which is a very promising finding."

This work extends and reinforces the findings of Seymour's previously published research which demonstrated that a grape-enriched diet reduced risk factors for heart disease and diabetes in obesity-prone rats.


'/>"/>

Contact: Justin Harris
juaha@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Related biology news :

1. Even in same vineyard, different microbes may create variations in wine grapes
2. RIT scientists decode 3 bacterial strains common to grapevines and sugarcane
3. A digital portrait for grapes indicates their ripeness
4. Compound in grapes, red wine could be key to fighting prostate cancer
5. Selective grazing and aversion to olive and grape leaves achieved in goats and sheep
6. NEIKER and INRA discover that BDA symptoms in grapevine leaves are a sign of esca
7. Eating grapes may help protect heart health in men with metabolic syndrome, new study suggests
8. Rise in sodium intake in US over last decade despite health officials call for reduction
9. Excess vitamin E intake not a health concern
10. High-carb intake in infancy has lifelong effects, UB study finds
11. Kids consumption of sugared beverages linked to higher caloric intake of food
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2017)... 29, 2017  higi, the health IT company that ... North America , today announced a Series B ... of EveryMove. The new investment and acquisition accelerates higi,s ... to transform population health activities through the collection and ... higi collects and secures data today on behalf ...
(Date:3/24/2017)... 24, 2017 Research and Markets has announced ... Analysis & Trends - Industry Forecast to 2025" report to ... The ... a CAGR of around 15.1% over the next decade to reach ... analyzes the market estimates and forecasts for all the given segments ...
(Date:3/22/2017)... 2017 Optimove , provider of ... such as 1-800-Flowers and AdoreMe, today announced two ... Replenishment. Using Optimove,s machine learning algorithms, these features ... replenishment recommendations to their customers based not just ... customer intent drawn from a complex web of ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... ... April 20, 2017 , ... NetDimensions appoints Bill Mastin, ... With over 20 years of experience in the learning technologies industry, Mastin joins NetDimensions ... within Learning Technologies Group plc (LTG). At LEO, Mastin served as SVP of the ...
(Date:4/20/2017)... ... April 20, 2017 , ... ... for advanced technology applications, announced today that Chief Executive Officer (CEO) Debbie Gustafson ... SEMI is the global industry association connecting the electronics manufacturing supply chain. ...
(Date:4/20/2017)... Bethesda, MD (PRWEB) , ... April 20, 2017 ... ... announce the formation of a unique intellectual property (IP) sharing and commercialization model. ... their most promising inventions. A main component of this effort is bringing the ...
(Date:4/20/2017)... N.J. and PETACH TIKVAH, Israel ... BCLI), a leading developer of adult stem cell technologies for ... Executive Officer, will present at the Alliance for Regenerative Medicine,s ... Day on Thursday, April 27, 2017 at 09:40 EDT in ... Ralph Kern , MD, MHSc, Chief Medical Officer & ...
Breaking Biology Technology: