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Grants awarded to help bring promising bioscience discoveries to market
Date:7/18/2011

a specific population of cells that produce autoantibodies. Drs. Marrack and Rubtsov recently reported the discovery of autoimmune-associated B cells (ABCs) and have applied for a patent on the method of depleting the ABCs to treat autoimmune disease. If the designed antibodies can cause the depletion of ABCs, the product could be modified for use in humans and become a powerful new tool for the treatment of a variety of autoimmune diseases.

Combining Pro-Oxidant Effects to Kill Cancer Cells
Investigators: Remy Kachadourian, PhD, and Brian J. Day, PhD

Drs. Kachadourian and Day have been awarded $29,649 to develop new and more efficient methods of reducing extracellular concentrations of the antioxidant glutathione to sensitize cancer cells to chemotherapy and radiation. The strategy may significantly impact cancer treatment by allowing the use of smaller treatment doses, therefore resulting in better patient tolerance and compliance. The project can potentially lead to the commercialization of a library of compounds that would be used in individualized medicine against cancer.


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Contact: William Allstetter
allstetterw@njhealth.org
303-398-1002
National Jewish Health
Source:Eurekalert

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