Navigation Links
Grant to study how cells sense electric fields

Learning how living cells can detect and respond to electric fields is the aim of a $570,000, three-year grant from the National Science Foundation to Min Zhao, professor of dermatology and ophthalmology at the UC Davis Health System and Center for Neuroscience.

Living cells are already known to respond to electric fields, as well as being able to sense light, temperature and chemical signals. Understanding this mechanism would establish a new biological signaling mechanism, with implications for engineering tissues and wound healing as well as in basic science, Zhao said.

Zhao and colleagues will use the grant to generate hundreds of thousands of genetic mutations in the amoeba Dictyostelium discoideum. They will collaborate with Tingrui Pan, professor of biomedical engineering, to develop methods to quickly screen thousands of mutant amoebae for those that do not respond to electric fields. Those defective amoebae will allow the scientists to home in on the genes and molecules responsible.

Dictyostelium was selected for the study because it is the simplest cell to work with that also moves, Zhao said.

In previous work, Zhao and his collaborators found that wounds generate a weak electric field that guides cells moving in to repair the wound.

"The big question is, how do the cells detect the electric field?" Zhao said. He believes that there is a molecule or set of molecules within cells that respond to electric fields.


Contact: Andy Fell
University of California - Davis

Page: 1

Related biology news :

1. UCs NIH grant brings technology from outer space to playgrounds
2. Seattle Childrens Hospital leads $23.7 million NIH grant to study gene repair
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
5. UGA Odum School of Ecology professor receives grant to study West Nile Virus in NYC
6. Genes and environment grant funds close look at nature-nurture overlap in common diseases
7. Mustafa alAbsi Ph.D. and national team awarded major NIH grant
8. NIH awards UC $9 million grant to improve patient point-of-care technologies
9. UAB wins $5.7M neurofibromatosis grant
10. Flu vaccine in painless skin patches under development at Emory, Georgia Tech with NIH grants
11. Study reveals that immigrant teenagers eat better than Spanish teenagers
Post Your Comments:
(Date:6/16/2016)... 2016 The global ... reach USD 1.83 billion by 2024, according to ... Technological proliferation and increasing demand in commercial buildings, ... drive the market growth.      (Logo: ... development of advanced multimodal techniques for biometric authentication ...
(Date:6/3/2016)... Das DOTM (Department ... hat ein 44 Millionen $-Projekt ... einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an Decatur ... Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale Anbieter ... aber Decatur wurde als konformste und innovativste ...
(Date:5/24/2016)... , May 24, 2016 Ampronix facilitates superior patient care by providing unparalleled ... medical LCD display is the latest premium product recently added to the range of ... ... ... Sony 3d Imaging- LCD Medical Display- Ampronix News ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... , ... Parallel 6 , the leading software as a service (SaaS) ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication between ... Using the CONSULT module, patients and physicians can schedule a face to face virtual ...
(Date:6/27/2016)... , June 27, 2016   Ginkgo Bioworks , ... industrial engineering, was today awarded as one of ... of the world,s most innovative companies. Ginkgo Bioworks ... for the real world in the nutrition, health ... work directly with customers including Fortune 500 companies ...
(Date:6/24/2016)... ... 2016 , ... Researchers at the Universita Politecnica delle Marche in Ancona combed ... pleural mesothelioma. Their findings are the subject of a new article on the Surviving ... signposts in the blood, lung fluid or tissue of mesothelioma patients that can help ...
(Date:6/23/2016)... /PRNewswire/ - FACIT has announced the creation of ... company, Propellon Therapeutics Inc. ("Propellon" or "the Company"), ... portfolio of first-in-class WDR5 inhibitors for the treatment ... represent an exciting class of therapies, possessing the ... cancer patients. Substantial advances have been achieved with ...
Breaking Biology Technology: