Navigation Links
Grant funded to improve mothers' nutrition before pregnancy and impact on baby
Date:12/17/2012

AURORA, Colo. (Dec. 17, 2012) The Regents of the University of Colorado are pleased to announce that the University of Colorado have been awarded a grant by the Bill & Melinda Gates Foundation. The grant,in the amount of more than $11 million, is to support research to normalize early growth of offspring of mothers in poor communities with high rates of early growth retardation. Michael Hambidge, MD, ScD, professor emeritus principal investigator and Nancy Krebs, MD, MS, professor both from the Nutrition Section, Department of Pediatrics, University of Colorado School of Medicine have the responsibility for the organization and conduct of this project.

Hambidge and Krebs have previously researched that it is not enough to provide babies with good nutrition after birth and are impressed with the growing evidence of the special importance of maternal nutrition before and in early pregnancy. Their objective is to determine the benefits to the babies of women in poor, food insecure environments by comparing the benefits of commencing a daily maternal multiple micronutrient-fortified lipid based nutrition supplement (with additional calories for underweight participants) at least three months prior to conception versus the benefits of commencing the same supplement at 12 weeks gestation. The offspring of each of these groups will also be compared with those of a concurrently randomized control group which receives the same home visits and education/support for hygiene and nutrition including breastfeeding. The equipment and experienced personnel are already in place at each site. The sites for the study will be in Guatemala, Pakistan, India, and Zambia.

"Many nutrition-related interventions, including some of our own, have had surprisingly little impact on reproductive outcomes, including especially postnatal infant growth. The evidence strongly points to the importance of extending the critical window to the health of the woman before she enters pregnancy because so much of the programming for later outcomes occurs in the very earliest days and weeks of gestation," Krebs said. "The challenge to improve the nutritional health of women before they become pregnant is very daunting, but the beneficial pay-off is potentially profound."

Upon hearing of the grant funding Hambidge said "With respect to the challenge ahead, it has become increasingly apparent that the cause of much of the excessive morbidity and mortality in poor, food insecure populations begins with poor nutrition in the parents, especially the mother. Moreover, there is increasing recognition that the early weeks of pregnancy and the parents' nutritional status before conception are of vital importance. Yet hard evidence is still very limited because of the research challenge imposed by the difficulty of predicting conception and of even being aware of the early critical days in the development of the baby. These may be adversely effected directly by a poor nutrition environment in utero or/and a little less directly by the adverse effects of a poor maternal environmental on her genome which is then passed on to effect the epigenome of the baby in utero and, we believe, after birth. The project is complex and will depend on multiple collaborations, globally and in this country and university. Preventing malnutrition of virtually all women of child-bearing age is a tremendous programmatic challenge, the value of which needs to be clearly defined to justify this huge addition to the many programs already funded to treat malnutrition in young children."

This grant runs for five years.


'/>"/>

Contact: Jackie Brinkman
jackie.brinkman@ucdenver.edu
303-724-1525
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. A fragrant new biofuel
2. Record-breaking grant: New research project to investigate the causes of mental disorders
3. WHOI researchers, collaborators receive $1.4 million grant to study life in oceans greatest depths
4. ASBMB wins National Science Foundation grant to enhance K-12 science education
5. Scientist wins $3 million renewal of one of longest-running NIH grants to Scripps Research
6. Kinesiology team gets $975,000 Defense grant to study effects of heavy loads on soldiers
7. Michael J. Fox Foundation grant to Dr. Samuel Young will provide Parkinsons drug development tools
8. UC Riverside receives grant for global health and development research
9. Biology professor secures grant to save West Virginias primary natural history collection
10. Lawson recieves Grand Challenges Explorations grant for groundbreaking research
11. Scripps Florida scientists awarded $8.4 million grant to develop new anti-smoking treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... 2016 The Department of Transport Management ... 44 million US Dollar project, for the , ... Personalization, Enrolment, and IT Infrastructure , to ... and implementation of Identity Management Solutions. Numerous renowned international vendors ... Decatur was selected for the most compliant and ...
(Date:5/20/2016)...  VoiceIt is excited to announce its new ... By working together, VoiceIt and VoicePass will offer ... take slightly different approaches to voice biometrics, collaboration ... usability. Both ... "This marketing and technology partnership allows ...
(Date:4/28/2016)... and BANGALORE, India , April 28, 2016 ... a product subsidiary of Infosys (NYSE: INFY ), ... a global partnership that will provide end customers ... mobile banking and payment services.      (Logo: ... innovation area for financial services, but it also plays a ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ("Biorem" ... by its major shareholders, Clean Technology Fund I, LP ... States based venture capital funds which together ... (on a fully diluted, as converted basis), that they ... their entire equity holdings in Biorem to TUS Holdings ...
(Date:6/27/2016)... ... 2016 , ... Newly created 4Sight Medical Solutions ... healthcare market. The company's primary focus is on new product introductions, to include ... are necessary to help companies efficiently bring their products to market. , The ...
(Date:6/24/2016)... 2016  Regular discussions on a range of subjects including ... two entities said Poloz. Speaking at a lecture ... , he pointed to the country,s inflation target, which is ... "In certain areas there ... common economic goals, why not sit down and address strategy ...
(Date:6/23/2016)... WA (PRWEB) , ... June 23, 2016 , ... ... announces the release of its second eBook, “Clinical Trials Patient Recruitment and Retention ... recruitment and retention in this eBook by providing practical tips, tools, and strategies ...
Breaking Biology Technology: