Navigation Links
Grant funded to improve mothers' nutrition before pregnancy and impact on baby
Date:12/17/2012

AURORA, Colo. (Dec. 17, 2012) The Regents of the University of Colorado are pleased to announce that the University of Colorado have been awarded a grant by the Bill & Melinda Gates Foundation. The grant,in the amount of more than $11 million, is to support research to normalize early growth of offspring of mothers in poor communities with high rates of early growth retardation. Michael Hambidge, MD, ScD, professor emeritus principal investigator and Nancy Krebs, MD, MS, professor both from the Nutrition Section, Department of Pediatrics, University of Colorado School of Medicine have the responsibility for the organization and conduct of this project.

Hambidge and Krebs have previously researched that it is not enough to provide babies with good nutrition after birth and are impressed with the growing evidence of the special importance of maternal nutrition before and in early pregnancy. Their objective is to determine the benefits to the babies of women in poor, food insecure environments by comparing the benefits of commencing a daily maternal multiple micronutrient-fortified lipid based nutrition supplement (with additional calories for underweight participants) at least three months prior to conception versus the benefits of commencing the same supplement at 12 weeks gestation. The offspring of each of these groups will also be compared with those of a concurrently randomized control group which receives the same home visits and education/support for hygiene and nutrition including breastfeeding. The equipment and experienced personnel are already in place at each site. The sites for the study will be in Guatemala, Pakistan, India, and Zambia.

"Many nutrition-related interventions, including some of our own, have had surprisingly little impact on reproductive outcomes, including especially postnatal infant growth. The evidence strongly points to the importance of extending the critical window to the health of the woman before she enters pregnancy because so much of the programming for later outcomes occurs in the very earliest days and weeks of gestation," Krebs said. "The challenge to improve the nutritional health of women before they become pregnant is very daunting, but the beneficial pay-off is potentially profound."

Upon hearing of the grant funding Hambidge said "With respect to the challenge ahead, it has become increasingly apparent that the cause of much of the excessive morbidity and mortality in poor, food insecure populations begins with poor nutrition in the parents, especially the mother. Moreover, there is increasing recognition that the early weeks of pregnancy and the parents' nutritional status before conception are of vital importance. Yet hard evidence is still very limited because of the research challenge imposed by the difficulty of predicting conception and of even being aware of the early critical days in the development of the baby. These may be adversely effected directly by a poor nutrition environment in utero or/and a little less directly by the adverse effects of a poor maternal environmental on her genome which is then passed on to effect the epigenome of the baby in utero and, we believe, after birth. The project is complex and will depend on multiple collaborations, globally and in this country and university. Preventing malnutrition of virtually all women of child-bearing age is a tremendous programmatic challenge, the value of which needs to be clearly defined to justify this huge addition to the many programs already funded to treat malnutrition in young children."

This grant runs for five years.


'/>"/>

Contact: Jackie Brinkman
jackie.brinkman@ucdenver.edu
303-724-1525
University of Colorado Denver
Source:Eurekalert

Related biology news :

1. A fragrant new biofuel
2. Record-breaking grant: New research project to investigate the causes of mental disorders
3. WHOI researchers, collaborators receive $1.4 million grant to study life in oceans greatest depths
4. ASBMB wins National Science Foundation grant to enhance K-12 science education
5. Scientist wins $3 million renewal of one of longest-running NIH grants to Scripps Research
6. Kinesiology team gets $975,000 Defense grant to study effects of heavy loads on soldiers
7. Michael J. Fox Foundation grant to Dr. Samuel Young will provide Parkinsons drug development tools
8. UC Riverside receives grant for global health and development research
9. Biology professor secures grant to save West Virginias primary natural history collection
10. Lawson recieves Grand Challenges Explorations grant for groundbreaking research
11. Scripps Florida scientists awarded $8.4 million grant to develop new anti-smoking treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2016)... FREMONT, Calif. , Dec. 15, 2016   ... a publicly held genomics technology company, announced today that ... the Listing Qualifications Department of The Nasdaq Stock Market ... the closing bid price of WaferGen,s common stock had ... days.  Accordingly, WaferGen has regained compliance with Listing Rule ...
(Date:12/15/2016)... , Dec. 15, 2016  There is much more ... or starting the engine. Continental will demonstrate the intelligence ... Las Vegas . Through the combination of the ... Entry) and biometric elements, the international technology company is ... personalization and authentication. "The integration of biometric ...
(Date:12/8/2016)... PUNE, India , Dec. 8, 2016 Market Research ... and Service Market. The global Mobile Biometric Security and Service Market ... period 2016 to 2022. Market Highlights: ... , , ... fast pace due to the increasing need of authentication and security ...
Breaking Biology News(10 mins):
(Date:1/23/2017)... N.J. , Jan. 23, 2017   Enteris ... feasibility study agreement with Sanofi to leverage ... delivery platform, Peptelligenceā„¢, to develop an oral formulation of ... Joel Tune , Chief Executive Officer and Executive ... is further validation of the tremendous value our Peptelligence ...
(Date:1/23/2017)... 2017  Alkahest Inc. ("Alkahest"), a biotechnology company ... and other age-related conditions, announced today that Sam Jackson, ... Medical Officer. In this role, Dr. Jackson will ... Alkahest and serve on the Executive Leadership Team.  ... Executive Director at Dynavax, where he led the Drug ...
(Date:1/21/2017)... ... ... Nipro Corporation (Osaka, Japan) and Transonic Systems Inc. (New York, USA) announced the ... sales rights for all non-OEM Transonic products in Japan. As partners for more than ... - Transonic JV is a natural next step to advance best practices and further ...
(Date:1/21/2017)... , Jan. 20, 2017 Aratana Therapeutics, ... company focused on the licensing, development and commercialization of ... Pharm,s Best Company in North America ... the award based on the FDA approval ... (grapiprant tablets), ENTYCE Ā® (capromorelin oral solution) and ...
Breaking Biology Technology: