Navigation Links
Grandpa's broken hip may mean weaker bones for his grandsons
Date:1/29/2010

The study, published in the Journal of Clinical Endocrinology & Metabolism, shows that hip fractures in grandfathers are linked to low bone density and reduced bone size in their grandsons.

"This is the first time this risk factor for low bone mass has been demonstrated across two generations," says associate professor Mattias Lorentzon, who led the research team at the Sahlgrenska Academy. "This new risk factor may be significant for the diagnosis of low bone mass and suggests possible mechanisms for the inheritance of low bone mass and fracture risk."

The study looked at around 3,700 grandparents and their grandsons from a national register. 270 of these grandsons had reduced bone density, in other words less bone mineral in their skeleton. All of these also had a grandparent who had broken their hip, as opposed to those who did not have any relatives who had broken a hip and had normal bone health.

"We then divided these men with reduced bone density into two groups," says Lorentzon. "In the first, we looked at those who had a grandmother who had broken a hip. In the second, we looked at whether a grandfather had suffered a hip fracture."

It emerged that the men who had a male relative who had suffered a fracture had up to 5% less bone density and 4% smaller bones than those who did not. By way of comparison, 10% less bone density can increase the risk of fractures as much as threefold.

In its study, the research team also took account of other risk factors for osteoporosis, such as smoking, physical activity, calcium intake, age, weight and gender.

"Despite these other risk factors, we could see that bone size is reduced and that this leads to lower bone density, which together means low bone mass a risk factor for osteoporosis. In other words, they run a greater risk of fractures in the future than their peers."

This finding could lead to improvements in the identification of patients at increased risk of osteoporosis.

"It's important for health professionals to ask whether grandparents have had hip fractures," says Lorentzon. "This is an important piece of the puzzle when it comes to the diagnosis and treatment of osteoporosis."


'/>"/>

Contact: Mattias Lorentzon
mattias.lorentzon@medic.gu.se
46-313-424-929
University of Gothenburg
Source:Eurekalert

Related biology news :

1. MIT: Mending broken hearts with tissue engineering
2. New journal shows half-broken gene is enough to cause cancer
3. Preventing a broken heart: Research aims to reduce scarring from heart attacks
4. Smart scaffolds may help heal broken hearts
5. CSHL-led team identifies key decision-point at which cells with broken DNA repair themselves or die
6. Award for pioneering stem cell research to mend broken bones
7. New strategy for mending broken hearts?
8. Influenza vaccine causes weaker immune response for children of rural Gabon than in semi-urban areas
9. Seagulls: Are males the weaker sex?
10. Men are the weaker sex
11. New research on structure of bones raises questions for treatment of osteoporosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... , June 9, 2016 ... deploy Teleste,s video security solution to ensure the safety of ... during the major tournament Teleste, an ... systems and services, announced today that its video security solution ... to back up public safety across the country. The ...
(Date:6/2/2016)... , June 2, 2016   The Weather Company , ... Watson Ads, an industry-first capability in which consumers will be ... able to ask questions via voice or text and receive ... Marketers have long sought an advertising ... that can be personal, relevant and valuable; and can scale ...
(Date:5/20/2016)... May 20, 2016  VoiceIt is excited to ... VoicePass. By working together, VoiceIt and ... VoiceIt and VoicePass take slightly different approaches to ... both security and usability. ... this new partnership. "This marketing and ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... June 23, 2016 , ... Mosio, a leader in ... Trials Patient Recruitment and Retention Tips.” Partnering with experienced clinical research professionals, Mosio ... practical tips, tools, and strategies for clinical researchers. , “The landscape of how ...
(Date:6/23/2016)... Houston Methodist Willowbrook Hospital has signed ... to serve as their official health care provider. ... will provide sponsorship support, athletic training services, and ... volunteers, athletes and families. "We are ... and to bring Houston Methodist quality services and ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... the launch of the Supplyframe Design Lab . Located in Pasadena, Calif., ... the future of how hardware projects are designed, built and brought to market. ...
(Date:6/23/2016)... , June 23, 2016 ... Hematology Review, 2016;12(1):22-8 http://doi.org/10.17925/OHR.2016.12.01.22 ... , the peer-reviewed journal from touchONCOLOGY, Andrew ... escalating cost of cancer care is placing an ... result of expensive biologic therapies. With the patents ...
Breaking Biology Technology: