Navigation Links
Got fish? Nutrition studies explore health benefits

This release is available in Spanish.

Some of America's most popular fish--salmon and albacore tuna, for example--are rich in healthful natural compounds known as omega-3 fatty acids. Ongoing studies by U.S. Department of Agriculture (USDA) chemist Darshan S. Kelley and co-investigators are helping uncover new details about how these fish-oil components help protect us from chronic diseases.

Kelley is with the USDA Agricultural Research Service (ARS) Western Human Nutrition Research Center at the University of California-Davis. ARS is the USDA's principal intramural scientific research agency.

In an early study with laboratory mice, Kelley and colleagues investigated the interplay of two omega-3 fatty acids from fish oilDHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid)and a third fatty acid, CLA (as trans-10, cis-12 CLA) found in some dietary supplements.

Kelley's 8-week test with 50 laboratory mice indicated that DHA protected the animals against two harmful side effects of CLA: CLA-induced insulin resistance and CLA-induced non-alcoholic fatty-liver disease. In contrast, EPA offered only partial protection against CLA-induced non-alcoholic fatty liver disease and provided no protection against insulin resistance.

If untreated, insulin resistance can lead to diabetes. An estimated 36 million to 57 million Americans are insulin-resistant. Non-alcoholic fatty liver disease can result in cirrhosis of the liver or liver cancer. The study appeared in a 2007 issue of Metabolic Syndrome and Related Disorders.

In related work, published in a 2009 article in Current Opinion in Clinical Nutrition and Metabolic Care, Kelley and University of California-Davis graduate student Dawn Fedor reviewed results from several dozen EPA and DHA studies. In their review, the scientists indicate that findings reported in the past decade have been inconsistent in regard to the effects of EPA and DHA on insulin resistance in human volunteers.

Their review underscores the need for new investigations, with larger numbers of volunteers. Kelley, for example, would like to determine whether DHA can improve the ability of adult, pre-diabetic volunteers to use insulin efficiently, and thus help delay onset of diabetes. Such research might reveal more about the mechanisms of action that DHA and EPA use, the sites upon which they act in the human body, and the genes that control these mechanisms.


Contact: Marcia Wood
United States Department of Agriculture -- Research, Education and Economics

Related biology news :

1. Killer catfish? Venomous species surprisingly common, study finds
2. Variety of foods -- the key for child nutrition
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Nutrition and bone health session to open the IOF World Congress on Osteoporosis in Bangkok
5. Consumer not ready for tailor-made nutrition
6. American Dietetic Association releases 2008 nutrition trends survey
7. Experts discuss applying systematic review to the field of nutrition
8. Rutgers receives US$10 million to establish Institute for Food, Nutrition and Health
9. Nutritional supplementation program helps prevent weight loss among children in African country
10. Results of the third school nutrition dietary assessment study published
11. Fighting obesity and illness with a novel approach to nutrition
Post Your Comments:
(Date:11/17/2015)... , Nov. 17, 2015  Vigilant Solutions announces today ... its Board of Directors. --> ... recently retiring from the partnership at TPG Capital, one ... with over $140 Billion in revenue.  He founded and ... all the TPG companies, from 1997 to 2013.  In ...
(Date:11/12/2015)... , Nov. 11, 2015   Growing need ... analytical tools has been paving the way for ... determination of discrete analytes in clinical, agricultural, environmental, ... being predominantly used in medical applications, however, their ... sectors due to continuous emphasis on improving product ...
(Date:11/9/2015)... 2015  Synaptics Inc. (NASDAQ: SYNA ), the ... entry into the automotive market with a comprehensive and ... of consumer electronics human interface innovation. Synaptics, industry-leading touch ... the automotive industry and will be implemented in numerous ... , Japan , and ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... Telbec/ - ProMetic Life Sciences Inc. (TSX: PLI) (OTCQX: PFSCF) ... Laurin , President and Chief Executive Officer of ProMetic, will ... 27 th Annual Healthcare Conference to be held at ... st , at 8.50am (ET) and ProMetic,s management ... The presentation will be available live via a webcast accessible ...
(Date:11/24/2015)... Va. , Nov. 24, 2015 ... focused on discovering drugs for metabolic disorders, announced ... to its Board of Directors (BOD). Mr. ... officer of Human Genome Sciences (HGS), and also ... Organization. Jim Powers , Chairman and ...
(Date:11/24/2015)... and NEW YORK , November 24, ... investment by Bristol-Myers Squibb in a European ... Bristol-Myers Squibb Company in which the companies will work ... immuno-oncology and other areas of unmet medical need. The collaboration ... LSP 5, the latest LSP fund. This is the first ...
(Date:11/24/2015)... -- According to two new studies, fewer men are having ... many doctors, scientists, and public health experts have been pushing ... tests being done, will there be more men dying of ... "Despite the efforts made in regards to early detection ... cause of death in men, killing approximately 27,500 men this ...
Breaking Biology Technology: