Navigation Links
Good diets fight bad Alzheimer's genes
Date:2/15/2011

Scientists today agree that there are five molecules that are known to affect or cause Alzheimer's disease, which plagues an estimated five million Americans. The potency of these molecules is linked to environmental factors such as diet and lifestyle.

Prof. Daniel Michaelson of Tel Aviv University's Department of Neurobiology at the George S. Wise Faculty of Life Sciences has illuminating news about one of these five molecules APOE, created by the apolipoprotein E. gene found in all of our bodies.

Prof. Michaelson says APOE comes in two forms, a "good" APOE gene and a "bad" APOE gene, called APOE4. He has developed animal models to investigate the effects of diet and environment on carriers of APOE4, the presence of which is a known risk factor for Alzheimer's. It appears in 50% of all Alzheimer's patients, and in 15% of the general population which due to APOE4 is the population which is at risk of getting the disease.

The good news? In preliminary results, the researchers are exhilarated to find that a diet high in Omega 3 oils and low in cholesterol appears to significantly reduce the negative effects of the APOE4 gene in mouse models.

Exercise is not enough and may be worse

In differentiating between the good and bad variants of the APOE gene, Prof. Michaelson and his team studied many variables. They determined that while a rich and stimulating environment is good for carriers of "good" APOE, the same environment has a negative effect on those at risk for Alzheimer's because they carry the APOE4 gene. While this environment stimulated the formation of new neuronal connections in the "good APOE" mice, it caused the death of brain neurons in the "bad APOE" mice. The stimulating environment included running wheels and tubes for hiding and sliding, as well as ropes and other toys for the mice to play on, replaced and updated with new toys weekly. Those in a non-stimulating environment had access to
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Mothers diets have biggest influence on children eating healthy
2. Personalized diets for elderly after hospitalization decreases mortality rates
3. New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
4. Why fad diets work well for some, but not others
5. TV food advertisements promote imbalanced diets
6. Studies on nutrients, gene expression could lead to tailored diets for disease prevention
7. New study shows teens who drink 100 percent fruit juice have more nutritious diets overall
8. Happy holidays from the groaning board; Western diets turn on fat genes
9. Do high-fat diets make us stupid and lazy?
10. ADA releases updated position paper on vegetarian diets
11. People of higher socioeconomic status choose better diets -- but pay more per calorie
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Good diets fight bad Alzheimer's genes
(Date:5/5/2015)... , May 5, 2015, NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market, reminds investors ... Chief Technology Officer, is presenting  at CARTES SECURE CONNEXIONS AMERICA ... 5-7, 2015. The three-day conference is organized ... is speaking in is themed Global Fraud: Where is ...
(Date:4/21/2015)... Canada , April 21, 2015 ... and evolving government policies are boosting access control systems ... According to a recently published report by ... Opportunities, 2020 ", the access control systems market in ... nearly USD1.2 billion by 2020.The access control systems market ...
(Date:4/14/2015)... , April 14, 2015  HYPR Corp. ... Online (FIDO ® ) Alliance tm , an ... FIDO members commit to share technology and collaborate ... that are interoperable, more secure and private, and ... biometric identity verification that protects sensitive user information ...
Breaking Biology News(10 mins):NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3
... 18.3.2013 In the fruit fly Drosophila , the functions ... intertwined - among other things they are involved in neurotransmitter ... of Biochemistry showed for the first time that flies cannot ... also raises new questions as to its function. Anna Ziegler, ...
... 18, 2013 Labrys Biologics Inc., a company focused on ... lead the development of RN-307, a Phase 2 ready anti-CGRP ... M.D., Ph.D., joins Labrys as chief medical officer, along with ... of project management; Michele Bronson , Ph.D., ...
... Researchers at Albert Einstein College of Medicine of Yeshiva ... found that macrophages white blood cells that play a key ... and eliminate the body,s red blood cells (RBCs). The findings could ... red blood cell production is thrown out of balance. The study, ...
Cached Biology News:Blind flies without recycling 2Blind flies without recycling 3Labrys Biologics Announces Key Executive Appointments 2Labrys Biologics Announces Key Executive Appointments 3Labrys Biologics Announces Key Executive Appointments 4White blood cells found to play key role in controlling red blood cell levels 2White blood cells found to play key role in controlling red blood cell levels 3
(Date:5/27/2015)... Calif. , May 27, 2015  Ceres, Inc. ... been awarded a U.S. patent for a genetic sequence ... areas such as research, product development and plant transformation. ... regulating key biosynthetic processes that are the target of ... other seed companies a commercial license to the innovation, ...
(Date:5/26/2015)... (PRWEB) May 26, 2015 The ... with the Max Planck Society establishing the ... Photonics. The center will link two of the world's ... will be only the third Max Planck Centre in ... international society for optics and photonics, was with ...
(Date:5/26/2015)... and HILDEN, Germany , ... N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... QIAGEN Clinical Insight ® (QCI™) bioinformatics content ... interpret and report on genomic variants identified in ... for the bioinformatics platform are in oncology, for ...
(Date:5/26/2015)... Global Stem Cells Group ... the company’s first cellular and regenerative medicine symposium in ... day, hands-on stem cell training class Oct. 10. The ... M.D., President of Therapeutic Confrontations (CONFTERA) in Barcelona. ... in regenerative medicine and recent advances in cellular therapies, ...
Breaking Biology Technology:Ceres Awarded Patent for Innovation in Soybean 2Ceres Awarded Patent for Innovation in Soybean 3Third Max Planck Centre in North America Inaugurated at University of Ottawa 2Third Max Planck Centre in North America Inaugurated at University of Ottawa 3QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 2QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 3QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 4QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 5Stem Cell Training, Inc. Announces First European Symposium on Cellular and Regenerative Medicine 2Stem Cell Training, Inc. Announces First European Symposium on Cellular and Regenerative Medicine 3
... how to make an exact cut on a metal rod. But ... carbon nanotube, with a diameter 1/50,000th the thickness of a human ... journal Proceedings of the Royal Society A , researchers at ... single-walled carbon nanotubes are cut, a finding that could lead to ...
... /PRNewswire-FirstCall/ - YM BioSciences Inc. (NYSE Amex: ... previously announced public offering of 25,000,000 common shares of ... US $37,650,000. In connection with the offering, the Company ... up to 3,750,000 additional common shares to cover over-allotments, ...
... Dec. 17, 2010 InterMune, Inc. (Nasdaq: ... team to prepare for the commercialization of Esbriet™ (pirfenidone) ... received a positive CHMP opinion that is now awaiting ... Chairman, Chief Executive Officer and President of InterMune, said, ...
Cached Biology Technology:How do you cut a nanotube? Lots of compression 2YM BioSciences Closes Public Offering of Common Shares 2YM BioSciences Closes Public Offering of Common Shares 3InterMune Announces Senior Leadership Appointments to Prepare for Launch of Esbriet™ (Pirfenidone) in Europe 2InterMune Announces Senior Leadership Appointments to Prepare for Launch of Esbriet™ (Pirfenidone) in Europe 3InterMune Announces Senior Leadership Appointments to Prepare for Launch of Esbriet™ (Pirfenidone) in Europe 4InterMune Announces Senior Leadership Appointments to Prepare for Launch of Esbriet™ (Pirfenidone) in Europe 5InterMune Announces Senior Leadership Appointments to Prepare for Launch of Esbriet™ (Pirfenidone) in Europe 6
...
... BD PhosFlow Perm/Wash Buffer I can be ... signaling proteins to permeabilize cells and to ... wash buffer. Because saponin-mediated cell permeabilization is ... keep the cells in the presence of ...
... Mouse polyclonal antibody raised against ... Immunogen: PPP4C ... a.a) partial recombinant protein with ... Accession Number: NM_002720 ...
... Thermomixer R offers maximum application versatility ... heating, and cooling. Its active heating/cooling ... and temperature control ranges. Five different ... micro test tubes, are available for: ...
Biology Products: