Navigation Links
Good diets fight bad Alzheimer's genes
Date:2/15/2011

Scientists today agree that there are five molecules that are known to affect or cause Alzheimer's disease, which plagues an estimated five million Americans. The potency of these molecules is linked to environmental factors such as diet and lifestyle.

Prof. Daniel Michaelson of Tel Aviv University's Department of Neurobiology at the George S. Wise Faculty of Life Sciences has illuminating news about one of these five molecules APOE, created by the apolipoprotein E. gene found in all of our bodies.

Prof. Michaelson says APOE comes in two forms, a "good" APOE gene and a "bad" APOE gene, called APOE4. He has developed animal models to investigate the effects of diet and environment on carriers of APOE4, the presence of which is a known risk factor for Alzheimer's. It appears in 50% of all Alzheimer's patients, and in 15% of the general population which due to APOE4 is the population which is at risk of getting the disease.

The good news? In preliminary results, the researchers are exhilarated to find that a diet high in Omega 3 oils and low in cholesterol appears to significantly reduce the negative effects of the APOE4 gene in mouse models.

Exercise is not enough and may be worse

In differentiating between the good and bad variants of the APOE gene, Prof. Michaelson and his team studied many variables. They determined that while a rich and stimulating environment is good for carriers of "good" APOE, the same environment has a negative effect on those at risk for Alzheimer's because they carry the APOE4 gene. While this environment stimulated the formation of new neuronal connections in the "good APOE" mice, it caused the death of brain neurons in the "bad APOE" mice. The stimulating environment included running wheels and tubes for hiding and sliding, as well as ropes and other toys for the mice to play on, replaced and updated with new toys weekly. Those in a non-stimulating environment had access to
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Mothers diets have biggest influence on children eating healthy
2. Personalized diets for elderly after hospitalization decreases mortality rates
3. New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
4. Why fad diets work well for some, but not others
5. TV food advertisements promote imbalanced diets
6. Studies on nutrients, gene expression could lead to tailored diets for disease prevention
7. New study shows teens who drink 100 percent fruit juice have more nutritious diets overall
8. Happy holidays from the groaning board; Western diets turn on fat genes
9. Do high-fat diets make us stupid and lazy?
10. ADA releases updated position paper on vegetarian diets
11. People of higher socioeconomic status choose better diets -- but pay more per calorie
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Good diets fight bad Alzheimer's genes
(Date:8/28/2015)... , August 28, 2015 ... and Training Market by Assessment Type (Pen & Paper ... Brain Training, Corporate Learning, Academic Research), Vertical and Region ... Assessment and Training Market to grow from USD 2.4 ... at a Compound Annual Growth Rate (CAGR) of 25.6% ...
(Date:8/25/2015)... CITY and BELLEVUE, Wash. ... leader in advanced robotic systems, announced today it will ... unmanned ground vehicle (UGV), at the National Tactical Officers ... The Guardian S is the first-ever ... culmination of years of research and in-field trials and ...
(Date:8/24/2015)... 24, 2015  Based on its recent analysis of the ... 2015 African Biometrics Company of the Year Award. DERMALOG is ... success in Africa . It has particularly ... has implemented one of the largest biometric mass applications in ... the Central Bank of Nigeria with ...
Breaking Biology News(10 mins):Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 2Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 3Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 4Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 2Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 3Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 4Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 5Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 6
... all terrorist attacks from 1970 to 2008 occurred in just ... rural areas, spurred on by domestic actors, according to a ... the Study of Terrorism and Responses to Terrorism (START), a ... based at the University of Maryland. The research was ...
... Nature Genetics today has found new evidence for ... 2 diabetes. The study found that people who carry rare ... higher risk of type 2 diabetes. The findings should ... could lead to the development of personalised treatments. Previous ...
... Nature Climate Change today finds that tropical vegetation ... Using a combination of remote sensing and field data, scientists ... University of Maryland were able to produce the first "wall-to-wall" ... m) of carbon storage of forests, shrublands, and savannas in ...
Cached Biology News:5 US urban counties lead 'Terror Hot Spots' list, but rural areas not exempt 25 US urban counties lead 'Terror Hot Spots' list, but rural areas not exempt 3Body clock receptor linked to diabetes in new genetic study 2The good news about carbon storage in tropical vegetation 2The good news about carbon storage in tropical vegetation 3
(Date:9/1/2015)... ... September 01, 2015 , ... GenoCAD, ... a groundbreaking new version of its flagship DNA design platform, which has been ... DNA sequences into numerous genetic parts, which in turn can be recombined using ...
(Date:8/31/2015)... ... August 31, 2015 , ... In ... its properties such as low carbon footprints and compostability. These properties can help ... based plastics. On the basis of applications, the market for biodegradable plastics can ...
(Date:8/31/2015)... Research and Markets ( http://www.researchandmarkets.com/research/53wxp3/israel_biomedical ) has announced the ... Growth, Trends & Forecasts (2014-2020)" report to their ... is estimated at $0.19 billion by 2018 at a ... The near future will bring biomedical sensors that are ... sensors can be set to trigger alerts when unpredictable ...
(Date:8/31/2015)... MARLBOROUGH, Mass. , Aug. 31, 2015 /PRNewswire/ ... biotechnology company focused on discovering and developing innovative ... ophthalmology, today announced that the 30-day review period ... Drug (IND) for ocular indications with the U.S. ... the IND is now active. ...
Breaking Biology Technology:GenoCAD Releases Combinatorial Design Tool to Optimize Protein Expression and Streamline DNA Synthesis Orders 2Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 2Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 3Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 4Biodegradable Plastics Market Growing at 10.8% CAGR to 2020 5Israel Biomedical Sensors Market 2015 - Growth, Trends & Forecasts to 2020 2RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 2RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 3RXi Pharmaceuticals Announces Advancements in its Ophthalmology Clinical Program with RXI-109 4
... 28, 2011 Qteros, Inc., the developer of a ... platform for the lowest-cost production of cellulosic ethanol, today ... throughout the month of May. Kevin A. ... for Qteros, will deliver an oral presentation at the ...
... 2011 Omnicare Clinical Research (CR), a leading global, ... has been acquired by Nautic Partners, LLC, a private ... the deal not only makes official the separation of Omnicare ... the company,s most visible step in a comprehensive two-year ...
... April 28, 2011 Reportlinker.com announces that ... in its catalogue: Case ... of biomarker identification and companion diagnostic co-development ... Introduction The ...
Cached Biology Technology:Qteros Management to Present at Upcoming Conferences in May 2Omnicare Clinical Research Acquired by Nautic Partners, LLC 2Omnicare Clinical Research Acquired by Nautic Partners, LLC 3Reportlinker Adds Case Study: Personalized Cancer Therapy - The era of biomarker identification and companion diagnostic co-development 2Reportlinker Adds Case Study: Personalized Cancer Therapy - The era of biomarker identification and companion diagnostic co-development 3
Liquid. 50 μg/ml in PBS, pH 7.4. PROTECT FROM LIGHT. A convenient form of propidium iodide useful for flow cytometry studies. RTECS SF7949600, CAS 25535-16-4, M.W. 668.4. ...
Lyophilized solid. Suitable for evaluating functional activity of human complement components and for other research requiring a high level of hemolytic activity. ...
... VersArray ChipWriter Pro systems are ... proteins, or other biological samples. VersArray ... for uniformity, spot density, and reproducibility ... a variety of substrates. Their modular ...
Thermal printer paper is used with the thermal printer for the VersaFluor fluorometry systems. Supplied as 10 rolls....
Biology Products: