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Glycans enter mainstream of biomedical science
Date:7/25/2011

imic host glycans or that produce enzymes to destroy them. And Richard Gallo, MD, PhD, professor of medicine, will investigate another glycan called hyaluronan and its role in inflammation. These highly collaborative studies of how glycans modulate the inflammatory process have relevance to a wide variety of diseases in which inflammation plays a major role, from cancer to heart attacks to infections.

"Glycobiology is a very important aspect of biological science that deserves a great deal of attention," said Shu Chien, MD, PhD, director of UC San Diego's Institute of Engineering in Medicine and an advisor to the PEG effort. "Dr. Varki and his colleagues are world leaders in this field. The funding of their excellent proposal will allow these talented scientists to work as a team to make innovative discoveries that will advance our fundamental knowledge and enable clinical translation to a variety of important diseases."

All of these projects will be strongly supported via Core facilities run by Nissi Varki, MD, professor of pathology and Core Director for multiple UCSD Histology Cores; Dzung Le, MD, PhD, director of the UCSD Murine Hematology and Coagulation Core Laboratory and Biswa Choudhury, technical director of the GRTC Glycotechnology Core.

Distinguished local advisors to the PEG include Michael Karin, PhD, Distinguished Professor of Pharmacology and Pathology at UCSD's Laboratory of Gene Regulation and Signal Transduction and Moores Cancer Center; Anjana Rao, PhD, adjunct professor of pharmacology and Professor at the La Jolla Institute of Allergy and Immunology; and Christopher Glass, MD, PhD, professor in the department of cellular and molecular medicine and the department of medicine.


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Contact: Scott LaFee
slafee@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert  

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