Navigation Links
Glue, fly, glue
Date:2/28/2010

e making up a fifth of the amino acids in fibroin.

The key difference between dry silks from moths and butterflies and wet silks from caddisflies is that the serines in the silk from caddisflies are "phosphorylated," meaning phosphates are added to the serines as the fibroin silk protein is synthesized.

"Phosphates are well-known adhesion promoters used in dental fixtures such as crowns or fillings," says Stewart. "They are also in latex paints that are water-based, and the phosphates increase the adhesion of those paints. The paint industry discovered this fairly recently. Caddisflies have been doing this for at least 150 million years."

The phosphates attached to the serines are negatively charged. Other amino acids in the protein are positively charged. Stewart found that is a key factor in making silk underwater. Chains of proteins each with alternating regions of positive and negative charges line up in parallel with positive and negative charges attracting each other.

"Imagine those chains aligned side-by-side, but staggered so the pluses and minuses are lined up, which then forms silk fibers with lots and lots of these protein chains in one fiber," Stewart says. "You wouldn't be able to make shirts out of it, but you might be able to make wet Band-Aids."

Stewart made a counterintuitive finding about how wet silks are made. "These fibroin proteins that make up the silks are water-soluble because of the electrical charges. Ironically and this is our hypothesis for now the association of those plus or minus charges makes them water-insoluble. This is how you make a silk fiber under water."

Comparison with amino acids from three other caddisfly species found great similarities, suggesting other caddisflies also use phosphorylation to spin silk underwater.

Stewart says caddisfly silk and sandcastle worm glue are similar: their proteins are heavily phosphorylated and have a large number of po
'/>"/>

Contact: Lee Siegel
leesiegel@ucomm.utah.edu
801-581-8993
University of Utah
Source:Eurekalert  

Page: 1 2 3 4 5

Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Glue, fly, glue
(Date:12/19/2014)... Dec. 18, 2014  23andMe, Inc., the leading personal ... that pinpoints fine-scale differences in genetic ancestry of individuals ... Since immigrants first arrived more than four ... has served as a meeting place for peoples ... and the ongoing mixing of peoples with African, European, ...
(Date:12/17/2014)... 2014 Research and Markets ( ... "Samsung Galaxy S5 - Home Button Synaptics ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... technology than the iPhone 5S, Samsung introduces for ... product. The Galaxy S5 home button ...
(Date:12/17/2014)... YORK , Dec. 15, 2014  HITLAB ... Good Clinical Practices (GCP) audit to confirm its ... (FDA) regulations. This accomplishment enables HITLAB to conduct ... utilizing the highest principles for patient safety and ... improve global healthcare access, quality, and delivery with ...
Breaking Biology News(10 mins):23andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... the U.S. Department of Energy,s Brookhaven National Laboratory have ... against human adenovirus, a cause of ailments ranging from ... published in FEBS Letters , a journal of ... researchers sifted through thousands of compounds to determine which ...
... from Uppsala University, Sweden, show that the key to ... and Creutzfeldt-Jakob disease may lie in the ribosome, the ... recently published in the Journal of Biological Chemistry ... by misfolding of prion proteins. Examples of prion diseases ...
... that has sickened thousands in Haiti came from a single ... the past three years as some have thought, according to ... open-access journal of the American Society for Microbiology. ... findings that indicate Vibrio cholerae bacteria were introduced ...
Cached Biology News:Scientists identify promising antiviral compounds 2Scientists identify promising antiviral compounds 3The ribosome -- a new target for antiprion medicines 2Genomes of cholera bacteria from Haiti confirm epidemic originated from single source 2Genomes of cholera bacteria from Haiti confirm epidemic originated from single source 3
(Date:12/24/2014)... MA (PRWEB) December 23, 2014 Earlier ... Dr. James L. Sherley, director of the Adult Stem ... on an often overlooked and under appreciated unique property ... Self-Renewal by Distributed Stem Cells: Misunderstood in the Past, ... message to congress participants. He gave the address ...
(Date:12/24/2014)... 23, 2014 According to Ross Selinger, President ... of ITRA Global, the national office market continues to be ... This is evidenced by the third quarter’s surprising 3.9% GDP, ... Low energy costs have held inflation down and the Fed ... the housing market remaining soft. , This solid economic news ...
(Date:12/24/2014)... The report expects global cell isolation and expansion ... provides a carefully analyzed data about the vital drivers, ... , Full Copy of Report @ http://bit.ly/1yUxy0T ... cell expansion will keep witnessing growth at an impressive ... be driven by rapid technological advancements, government funding and ...
(Date:12/24/2014)... Dec. 23, 2014 Vermillion, Inc. (Nasdaq: ... gynecologic disease, announced today that investors including Oracle ... Fund LLC and several Vermillion directors have agreed ... of Vermillion,s common stock and warrants to purchase ... private placement.  Under the terms ...
Breaking Biology Technology:Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 2The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 - New Research Report by MarketsandMarkets 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5
... Inc., a division of GE Industrial Systems, announced ... a Green Bay manufacturing software development company. , ... Execution Systems (MES) technology for the manufacturing of ... as well as for pulp and paper products. ...
... to fighting breast cancer, and GE Medical Systems, headquartered ... AD and Second Look Digital are computer-aided detection (CAD) ... digital mammography system. CADx Systems, Inc. developed the Second ... the review of breast exams. , ,GE is ...
... until he gets to the better drugs, faster part of ... behind the Madison-based companys products is likely to hit the ... age when diseases and treatments become as common in conversation ... and a half-year-old company that Vodenlich joined as president earlier ...
Cached Biology Technology:Green Bay Software Company Purchased by GE 2New Technology in Fight against Breast Cancer 2Chipping Away at Drug Development 2Chipping Away at Drug Development 3
MAGP-2 (C-19)...
Laminin gamma-2 (G-16)...
... Proliferation Kit, For 100 slides. Immunocytochemistry.Sample ... in vitro tissue labeling.Recommended cell number: ... (labeling 1-2 hours).Store at 2-8 C ... Category: Drug Screening & Cellular Assays, ...
Dysadherin 2 (L-15)...
Biology Products: