Navigation Links
Glowing worms illuminate the roots of behavior
Date:11/14/2013

rocesses in real time.

Numerous studies have been done by "worm labs" around the world exploring various neurological processes in C. elegans. These have typically been done using one worm at a time, with the animal's body fixed in place on a slide. In their new paper, Albrecht's team details how they imaged, recorded, and analyzed specific neurons in multiple animals as they wormed their way around a custom-designed microfluidic array, called an arena, where they were exposed to favorable or hostile sensory cues.

Specifically, the team engineered a strain of worms with neurons near the head that would glow when they sensed food odors. In experiments involving up to 23 worms at a time, Albrecht's team infused pulses of attractive or repulsive odors into the arena and watched how the worms reacted. In general, the worms moved towards the positive odors and away from the negative odors, but the behaviors did not always follow this pattern. "We were able to show that the sensory neurons responded to the odors similarly in all the animals, but their behavioral responses differed significantly," Albrecht said. "These animals are genetically identical, and they were raised together in the same environment, so where do their different choices come from?""

In addition to watching the head neurons light up as they picked up odor cues, the new system can trace signaling through "interneurons." These are pathways that connect external sensors to the rest of the network (the "worm brain") and send signals to muscle cells that adjust the worm's movement based on the cues. Numerous brain disorders in people are believed to arise when neural networks malfunction. In some cases the malfunction is dramatic overreaction to a routine stimulus, while in others it is a lack of appropriate reactions to important cues. Since C. elegans and humans share many of the same genes, discovering genetic causes for differing neuronal responses in worms cou
'/>"/>

Contact: Michael Cohen
mcohen@wpi.edu
508-868-4778
Worcester Polytechnic Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Natures glowing slime: Scientists peek into hidden sea worms light
2. Scientists shed light on glowing materials
3. Tissue loss triggers regeneration in planarian flatworms
4. Rutgers study: Worms may shed light on human ability to handle chronic stress
5. Thermal limit for animal life redefined by first lab study of deep-sea vent worms
6. Invasion of the slugs -- halted by worms...
7. Bizarre bone worms emit acid to feast on whale skeletons
8. Fat worms inch scientists toward better biofuel production
9. Thailand: Astonishing 10 new species of semi-aquatic freshwater earthworms revealed
10. Waste removal in worms reveals new mechanism to regulate calcium signaling
11. What do leeches, limpets and worms have in common? Now, a sequenced genome
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Glowing worms illuminate the roots of behavior
(Date:4/23/2014)... is a technique used to read quickly. It ... skipping non-essential words and/ or sentences. Similarly to ... to quickly "read" genetic information. Genes that need ... the smaller the encoding message, the easier it ... from Instituto Gulbenkian de Cincia (IGC, Portugal) and ...
(Date:4/22/2014)... of Yale researchers will lead a five-year, $3 million ... events is affecting the transport of dissolved organic matter ... say could alter the chemical composition and water quality ... funding from the National Science Foundation,s MacroSystems Biology program, ... the watershed, which begins in Canada and runs through ...
(Date:4/22/2014)... International Science Consortium Ltd.,s nanotechnology expert will present a ... hazard assessment" at the 7th International Nanotoxicology Congress ... Turkey. , Dr. Monita Sharma will outline a ... National Academy of Sciences, " Toxicity Testing in the ... recommends use of non-animal methods involving human cells and ...
Breaking Biology News(10 mins):Cell division speed influences gene architecture 2Connecticut River watershed study will assess impacts of extreme rain events 2Connecticut River watershed study will assess impacts of extreme rain events 3
... 2012 The Crop Science Society of America (CSSA) announces ... their Annual Meetings, Oct. 21-24, 2012 in Cincinnati, OH. Members ... achievements and meritorious service. Only 0.3 percent of the Society,s ... class of CSSA Fellows are: Marc C. Albertsen, ...
... biological cells like a skin. They also surround organelles ... division. Scientists have long known in principle how biomembranes ... a role in maintaining the optimal distance between neighboring ... with the help of computer simulations, scientists of the ...
... Bioluminescence may play a key role in successful foraging ... research published Aug. 29 in the open access journal ... led by Jade Vacqui-Garcia, monitored the diving behaviour of ... Ocean that were also equipped with light detectors. The ...
Cached Biology News:Crop Science Society of America presents 2012 class of fellows 2Crop Science Society of America presents 2012 class of fellows 3Keep your distance! Why cells and organelles don't get stuck 2
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 ... Almshouse Road, Warrington, Pa. , Details: The Hepatitis ... finding a cure for hepatitis B and improving the quality ... Crystal Ball on Friday, April 11 at Warrington Country Club ...
(Date:1/14/2014)... NY (PRWEB) January 14, 2014 EquitiesIQ, ... Alliqua, Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical ... serve the wound care market. , Free report download: ... restructured with a seasoned management team and Board, which ...
(Date:1/14/2014)... , Jan. 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: ... and commercializing innovative therapies addressing major unmet medical ... received the Notice of Allowance from the United ... self-delivering RNAi compounds (sd-rxRNA®), for the treatment of ...
(Date:1/14/2014)... Rochester, NY (PRWEB) January 14, 2014 During ... is now known as “The Doctor’s Plague.” In this time ... their hands. This led, at times, to the death of ... staff today don’t know that they may be unwittingly transmitting ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... EASTON, Mass., March 6 Pressure,BioSciences, Inc. (Nasdaq: ... teleconference to discuss its 2007 financial results and to ... teleconference either,by telephone or through a live web-cast. The ... March 12, 2008, Time: 4:30 p.m. Eastern Daylight ...
... to Support European Partnerships, ALAMEDA, Calif., and ... collaboration with Novartis Pharma AG to give Novartis,access ... Technology Access Program (ETAP). Terms of the collaboration,were ... opening of a,facility in Paris, France to support ...
... Recently the State of,Brandenburg, and the EU, ... Alcat Europe, GmbH, covering marketing and employee costs ... laboratory company located in the BioTech Park in,Hennigsdorf ... food and,chemical sensitivities through the Alcat test method. ...
Cached Biology Technology:Pressure BioSciences, Inc. to Discuss 2007 Financial Results and Provide Business Update 2Singulex Collaborates With Large Pharmaceutical Company in Erenna(TM) Technology Access Program 2European Union, State of Brandenburg, Award Grants to Alcat Europe, GmbH 2
... Sequencer 20 System revolutionizes DNA sequencing, delivering ... The Genome Sequencer 20 System includes: ... and consumables for library construction, amplification, and ... de novo assembly The ...
... The RapidVUE is a particle shape and ... has been designed with the utmost simplicity in ... sample delivery module and an optical bench. The ... allows for easy upgrade for different applications such ...
... The ProteoSpin Detergent Clean-up Micro Kit provides ... removal of SDS, Triton X-100 and other detergents ... spin-column chromatography using Norgens patented protein resin as ... processing 2 50 g of either acidic or ...
... degradation is critical to the maintenance ... regulatory proteins as important and diverse ... heat shock and stress response, antigen ... and ion channels, cell cycle regulation, ...
Biology Products: