Navigation Links
Giant fire-bellied toad's brain brims with powerful germ-fighters
Date:4/13/2011

Frog and toad skins already are renowned as cornucopias of hundreds of germ-fighting substances. Now a new report in ACS's Journal of Proteome Research reveals that the toad brains also may contain an abundance of antibacterial and antiviral substances that could inspire a new generation of medicines.

Ren Lai and colleagues point out that scientists know little about the germ-fighting proteins in amphibian brains, despite many studies showing that amphibians synthesize and secrete a remarkably diverse array of antimicrobial substances in their skin. So they decided to begin filling that knowledge gap by analyzing brains from the Giant Fire-Bellied Toad and the Small-webbed Bell Toad.

They discovered 79 different antimicrobial peptides, the components of proteins, including 59 that were totally new to science. The diversity of the peptides "is, to our knowledge, the most extreme yet described for any animal brains," they noted. Some of the peptides showed strong antimicrobial activity, crippling or killing strains of staph bacteria, E. coli, and the fungus that causes yeast infections in humans. These promising findings suggest that the toad brains might be a valuable source for developing new antibacterial and antiviral drugs.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. 1,000 tags reveal mysteries of giant bluefin tuna
2. Conservation International gets support from Dreamworks Animation to protect giant pandas
3. Discovery of giant roaming deep sea protist provides new perspective on animal evolution
4. Doubling a gene in corn results in giant biomass
5. Tall tale of giant stingray circles the globe
6. Doubling a gene in corn results in giant biomass
7. Scientists rebuild giant moa using ancient DNA
8. Report documents the risks of giant invasive snakes in the US
9. Canopy giants and miniature fungi among 250 new species discovered in Kews 250th anniversary year
10. Microorganism may provide key to combating giant salvinia throughout Louisiana
11. Giant panda genome reveals new insights into the bears bamboo diet
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/3/2017)... A new independent identity strategy consultancy firm announces its ... to fill a critical niche in technical and policy ... Mark Crego and Janice Kephart together ... that span federal governments, the 9/11 Commission, private industry, ... has a common theme born from a shared passion ...
(Date:2/1/2017)... , February 1, 2017 IDTechEx Research, a ... emerging technology, announces the availability of a new report, Sensors ... Continue Reading ... ... and collaborative robots. Source: IDTechEx Report "Sensors for Robotics: Technologies, Markets ...
(Date:1/26/2017)...  Acuity Market Intelligence today released the 2017 ...  Acuity characterizes 2017 as a "breakout" year for ... a new understanding of the potential benefits these ... identity are often perceived as threats to privacy ... of Acuity Market intelligence. "However, taken together these ...
Breaking Biology News(10 mins):
(Date:2/16/2017)... 2017   Biostage, Inc. (Nasdaq: ... developing bioengineered organ implants to treat cancers and other ... today the closing on February 15, 2017 of its ... stock and warrants to purchase 20,000,000 shares of common ... offering was priced at $0.40 per share of common ...
(Date:2/16/2017)... , Feb. 16, 2017  Dermata Therapeutics, ... products to treat a variety of dermatological diseases, ... Series 1a financing and entered into a $5 ...  Dermata intends to use the capital for general ... major advancements in the treatment of serious diseases ...
(Date:2/16/2017)... Pa. , Feb. 16, 2017  Windtree ... biotechnology company focusing on developing aerosolized KL4 surfactant ... from a preclinical influenza study showed that aerosolized ... survival in a well-established preclinical animal model. The ... a growing body of evidence that supports the ...
(Date:2/16/2017)... ... February 16, 2017 , ... ... extended its industry leading Biochemistry Services specifically targeting the rapidly growing needs ... methods for the biochemical and biosimilar characterization , product-related impurity characterization, ...
Breaking Biology Technology: