Gerton Lab determines the composition of centromeric...(reinforce the importance of both structu...)

Date:9/28/2009

reinforce the importance of both structure and function of octameric nucleosomes in the epigenetic propagation of centromeric chromatin," said Raymond Camahort, Ph.D., formerly a Postdoctoral Research Associate and lead author on the paper. "In order to better understand how centromeric nucleosomes are formed, we must understand their composition. This work has answered a critical question of structure."

"Many lines of evidence indicate that centromeric chromatin is evolutionarily conserved from yeast to man," said Jennifer Gerton, Ph.D., Associate Investigator and senior author on the paper. "The octameric structure for centromeric nucleosomes may be universal. Our studies in budding yeast help to shed light on mechanisms of centromere propagation and chromosome transmission that are needed to maintain human health."

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Contact: Marie Jennings mfj@stowers.org 816-926-4015 Stowers Institute for Medical Research Source:Eurekalert

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