Navigation Links
Germany starts its part in the International Cancer Genome Project
Date:12/9/2009

Brain tumors are the primary cause of cancer mortality in children. Even if a cure is possible, young patients often suffer tremendously from the stressful treatment which can be harmful to the developing brain. Therefore, there is an urgent need for target-oriented, gentle treatment methods. The most important childhood brain tumors are medulloblastoma, which is diagnosed in approximately one hundred young patients each year in Germany, and pylocytic astrocytoma, which is diagnosed in about 200 children each year. "Regarding these two conditions, in particular, we have done good preliminary work and have already compiled comprehensive tumor sample collections," explains Professor Peter Lichter, coordinator of the German ICGC network.

The German ICGC research network will analyze 300 tumor samples of each cancer type. In addition, researchers will analyze the same number of healthy samples obtained from the same patients so as to be able to identify cancer-specific changes. In the more common adult cancers, ICGC regulations even require the investigation of 500 samples of each type of cancer.

The decisive factor for the start of the International Cancer Genome Consortium were U.S. studies of colorectal cancer and breast cancer which showed that in each individual tumor considerably more mutations are crucial for carcinogenesis than scientists had previously assumed. Furthermore, individual tumors of one and the same type of cancer have substantially different mutation profiles. This may lead to totally new treatment approaches in each individual case; in some cases, a cocktail of several targeted drugs might also improve the chances of cure.

Distributed Tasks: Collecting, Sequencing, Analyzing

The various tasks of the German ICGC network are headed by internationally acclaimed experts. The common goal is a very comprehensive molecular analysis of the tumors. Thus, besides targets for new therapies, scientists are a
'/>"/>

Contact: Dr. Sibylle Kohlstaedt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Martin Hensen, head of e-strategies, UCB Germany: Making e-marketing more than just an add-on
2. Alzheimers starts earlier for heavy drinkers, smokers
3. Obesity starts in the head? 6 newly discovered genes for obesity have a neural effect
4. Food security: It starts with seed
5. Research vessel Polarstern starts 24th Arctic season
6. BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo
7. ESMO International Symposium on Immunology
8. Conservation International and Toyota partner to protect Philippines rain forests
9. International team shows mercury concentrations in fish respond quickly to increased deposition
10. International team shows mercury concentrations in fish respond quickly to increased deposition
11. BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/12/2015)... , Aug. 12, 2015  New research ... can attack Android phones to steal users, fingerprints. ... increasing availability of fingerprint scanners on mobile devices, ... concern. To secure biometrics on mobile devices, HYPR ... augment these convenient authentication systems with strong cryptographic ...
(Date:8/6/2015)... CITY, Calif. , Aug. 6, 2015 /PRNewswire/ ... Valley) will visit Crossmatch ™ to learn ... networks and protect data. Crossmatch is a world ... whose technologies and expertise are helping federal agencies ... efficiency and security.   "The vast ...
(Date:8/5/2015)... VIEW, Calif. , Aug. 5, 2015 ... exhibits continuous growth in applications, penetration into newer sectors, ... after year. The global biosensors space has seen the ... exited the market so far. (Photo - ... Frost & Sullivan, Analysis of the Global Biosensors ...
Breaking Biology News(10 mins):HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 2HYPR Corp. Addresses Android Vulnerability That Exposes Ecosystem-wide Biometric Security Challenges 3Rep. Honda to Visit Crossmatch in Redwood City 2Innovative Biosensors Incite Use in Non-Traditional Applications 2Innovative Biosensors Incite Use in Non-Traditional Applications 3Innovative Biosensors Incite Use in Non-Traditional Applications 4
... A study led by researchers from Universitat Autnoma de Barcelona ... populations control the way they spread over the surface of ... presence of an antibiotic, only to resume again when the ... RecA protein, which significantly increases its concentration at the start ...
... in San Diego, picked up a copy of the Los Angeles ... on the wildfires in the western United States. The wildfires, ... years instead of every few decades and they are burning ... cheatgrass (Bromus tectorum), an invasive plant that is rapidly displacing native ...
... 2010 -- With the signing of a memorandum of ... 20 planned core ecological observatory sites that will provide ... ecosystem breathes. The agreement between the Department of ... Walker Branch Watershed portion of the $434 million project ...
Cached Biology News:Discovery of controlled swarm in bacteria 2In elevated carbon dioxide, soybeans stumble but cheatgrass keeps on truckin' 2In elevated carbon dioxide, soybeans stumble but cheatgrass keeps on truckin' 3In elevated carbon dioxide, soybeans stumble but cheatgrass keeps on truckin' 4In elevated carbon dioxide, soybeans stumble but cheatgrass keeps on truckin' 5DOE, ORNL officially join NSF on massive ecological study 2
(Date:9/3/2015)... (PRWEB) , ... September 03, 2015 , ... ... release its non-invasive hydration monitoring wearable early 2016. , The device, called ... using proprietary optical and electrical sensing technology. These sensors track trending interstitial ...
(Date:9/2/2015)... (PRWEB) , ... September 02, ... ... provider of regulatory compliance, quality systems, analytical testing, education and consulting services ... with expertise in medical device products/processes development, design control, validation, quality assurance ...
(Date:9/2/2015)... , Sep. 02, 2015 ... announced the addition of Jain PharmaBiotech,s new report ... to their offering. This report follows ... characteristic that can be objectively measured and evaluated ... processes as well as pharmacological responses to a ...
(Date:9/2/2015)... ... September 02, 2015 , ... ... botanical and plant-derived compounds. BCC Research reveals in its new report that ... this market defines the category and generates the most market demand. , ...
Breaking Biology Technology:Technology Startup Halo Wearables to Unveil Non-Invasive Hydration Monitoring Device Early 2016 2NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 2NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 3NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 4NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 5NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 6NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 7Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 2Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 3Plant-derived Compounds Poised to Assume Greater Role in Global Drug Markets, According to BCC Research 2Plant-derived Compounds Poised to Assume Greater Role in Global Drug Markets, According to BCC Research 3
... company adds new apoAI measurement and apoB/apoAI ratio to ... March 17 /PRNewswire/ -- Atherotech, ... Cholesterol Test in booth #1263 at ACC.09, the American ... The annual meeting takes place March 29-31, 2009, at ...
... Mass., March 17 The pro bono healthcare ... ), has announced that its newly instituted Safe ... Lutheran Health System of La Crosse, Wisconsin. The ... outstanding accomplishments in safe patient handling, safe lifting, ...
... March 17 Cardiorobotics, Inc., a ... use in a wide range of applications, including: ... appointment of Dr. Samuel Straface in the position ... that Dr. Straface has joined Cardiorobotics in this ...
Cached Biology Technology:Atherotech to Exhibit the VAP(R) Cholesterol Test at ACC.09 in Orlando 2Atherotech to Exhibit the VAP(R) Cholesterol Test at ACC.09 in Orlando 3Gundersen Lutheran Health System is Recognized for Safe Lifting Leadership 2Gundersen Lutheran Health System is Recognized for Safe Lifting Leadership 3Cardiorobotics Announces New CEO, PLSG Executive-in-Residence to Lead Company 2Cardiorobotics Announces New CEO, PLSG Executive-in-Residence to Lead Company 3
High-throughput DNA sequencing of any library. Just give us your transformation mixture, and we'll do the rest. ABI 3730xl's yield the longest read lengths available. LIMS tracking utilizing Geospiza...
... pass sequencing of plasmids and PCR ... our high performance sequencing pipeline which ... per day. The key benefits we ... are rapid turnaround, high sequencing pass ...
... high quality whole genome sequencing service. Our ... allow even the smallest of laboratories to ... features which set our whole genome sequencing ... strategies, proprietary assembly software, rapid project turnaround ...
Shotgun library construction and high-throughput DNA sequencing of microbial genomes, BACs, adenoviruses, phosmids and cosmids. LIMS tracking utilizing Geospiza's Finch system....
Biology Products: