Navigation Links
Germ-fighting vaccine system makes great strides in delivery
Date:5/20/2013

SAN DIEGO (May 20, 2013) - A novel vaccine study from South Dakota State University (SDSU) will headline the groundbreaking research that will be unveiled at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference (NBC). The meeting takes place Monday, May 20 - Wednesday, May 22 at the Sheraton San Diego Hotel and Marina.

"The main goal of a vaccine is to stimulate the immune system to fight against a pathogen that causes the disease", explained Dr. Hemachand Tummala, assistant professor of Pharmaceutical Sciences at SDSU. "We want to make a delivery system that mimics pathogens in stimulating the immune system but not cause infection."

Tummala and his doctoral student, Sunny Kumar, used inulin acetate taken from a fiber derived from tubers, such as dahlias or chicory. "The fiber is natural, inexpensive and easily accessible", Tummala stated. "Most importantly, it acts as a PAMP [pathogen-associated molecular pattern]. We made pathogen-like nanoparticles with inulin acetate and incorporated pathogen-related antigens inside them." Tummala explained, "Once the antigen presenting cells sense these particles as pathogens, they eat them and process them as PAMPs." This then aggravates the immune system.

The researchers then tested the technology in preventing a viral disease. Tummala collaborated with Dr. Victor Huber, assistant professor and infectious disease specialist at the Sanford School of Medicine, whose research focuses on influenza.

The researchers then tested the efficiency of the vaccine delivery system in mice against a lethal challenge of the 2009 pandemic H1N1 flu virus. One group of mice was not immunized, while the others received a vaccine containing one or two antigens. Within eight days, 90 percent of the unvaccinated mice died. Those who received one antigen contracted the flu, and all but one recuperated. None of those who received the vaccine with two antigens a
'/>"/>

Contact: Kimberly Brown
BrownK@aaps.org
703-248-4772
American Association of Pharmaceutical Scientists
Source:Eurekalert

Page: 1 2

Related biology news :

1. Rotavirus vaccine developed in India demonstrates strong efficacy
2. Quest for edible malarial vaccine leads to other potential medical uses for algae
3. Bird flu mutation study offers vaccine clue
4. Vaccine adjuvant uses host DNA to boost pathogen recognition
5. Cleverly designed vaccine blocks H5 avian influenza in models
6. HPV vaccine trends point to failures in patient education, vaccine programs
7. Cancer vaccines self-sabotage, channel immune attack to injection site
8. Human trials for Streptococcus A vaccine
9. Novel aptamer boosts T cell-based immune response to therapeutic vaccines
10. Designer bacteria may lead to better vaccines
11. UMMS experts seek better flu vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... The Defense Logistics Agency is insourcing its efforts ... microcircuits from entering into its supply chain. ... initiative dubbed DNA marking. The capability will validate the ... the supply chain. The new quality control measures will ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... "Global Facial Recognition Market 2015-2019" report to ... Facial recognition is a technology used for ... overall facial feature of a person such as nose, ...
(Date:12/10/2014)... , Dec. 8, 2014 You,ve been here before: you desperately ... your password, site key or the answer to your secret question. ... Today, Hoyos Labs , a digital infrastructure security ... end to the frustration that comes with usernames, passwords and PINs ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and ... revealed new insights into how sex chromosomes are regulated. ... that males have only one copy of the sex ... between male and female sex chromosomes in fruit flies ...
... have come together to announce funding for new projects ... in the emerging field of synthetic biology. The Biotechnology ... and Physical Sciences Research Council (EPSRC) have awarded funding ... UK researchers to build links across institutions and discipline ...
... fruit fly circling your week-old peach has helped scientists ... eggshell formation. The paradoxical finding gives scientists a ... forms as it points to a likely target for ... the Medical College of Georgia Schools of Medicine and ...
Cached Biology News:X chromosome exposed 2New projects to raise UK profile in synthetic biology 2Fruit fly helps identify protein critical to eggshell formation that may be pesticide target 2Fruit fly helps identify protein critical to eggshell formation that may be pesticide target 3
(Date:1/22/2015)... Medical Systems (NYSE: VAR ), world leader in ... to sustainability with inclusion on a prestigious list of the ... equipment company among the Corporate Knights Global 100 Most Sustainable ... Davos, Switzerland . "We ...
(Date:12/24/2014)... 2014  United Therapeutics Corporation (NASDAQ: UTHR ) ... ) has submitted a pre-market approval application to the ... of Medtronic,s SynchroMed ® II implantable drug infusion ... United Therapeutics, Remodulin ® (treprostinil) Injection delivered intravenously ...
(Date:12/24/2014)... December 23, 2014 “Preparative & ... HPLC, Flash), Consumables (Columns, Solvents, Buffers, Valves, Guages, ... & Agriculture) - Forecasts to 2019” provides a ... opportunities, current market trends, and strategies impacting the ...
(Date:12/24/2014)... MD (PRWEB) December 23, 2014 On ... H.R. 83, the Omnibus and Continuing Resolution Appropriations Act ... a condition eligible to receive funding through the Congressionally ... of Defense (DoD). The Hydrocephalus Association (HA), working in ...
Breaking Biology Technology:Varian Honored Among World's 100 Most Sustainable Corporations 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2
... Ardea Biosciences, Inc. (Nasdaq: RDEA ) announced ... officer, will present at the Oppenheimer 21st Annual Healthcare Conference ... at 10:50 a.m. EDT on Tuesday, November 2, 2010. ... accessed on the Investor Relations section of Ardea,s website at ...
... lot of waste products, but one of these, eggshells, could ... International Journal of Global Warming this month. ... demonstrated that the membrane that lines an eggshell can absorb ... carbon dioxide from the atmosphere. The carbon dioxide thus trapped ...
... 26 BioMed Realty Trust, Inc. (NYSE: ... announced acquisition of the Science Center at Oyster Point ... campuses in the South San Francisco life science market, ... of laboratory, office and industrial space. The properties were ...
Cached Biology Technology:Ardea Biosciences to Present at the Oppenheimer 21st Annual Healthcare Conference 2Scrambling for climate change solutions 2BioMed Realty Trust Completes South San Francisco Portfolio Acquisition 2BioMed Realty Trust Completes South San Francisco Portfolio Acquisition 3BioMed Realty Trust Completes South San Francisco Portfolio Acquisition 4
Bovine Serum Albumin Peroxidase Stabilizer Solution, 1 L...
SAIVI Alexa Fluor 680 injectable contrast agent *bovine serum albumin*...
... Lysate contains the cellular components necessary for ... elongation and termination factors) but has not ... is used primarily for the isolation of ... of endogenous globin mRNA. Untreated Lysate is ...
RAT ANTI MOUSE METALLOPHILIC MACROPHAGES...
Biology Products: