Navigation Links
Geography and history shape genetic differences in humans
Date:6/5/2009

New research indicates that natural selection may shape the human genome much more slowly than previously thought. Other factors -- the movements of humans within and among continents, the expansions and contractions of populations, and the vagaries of genetic chance have heavily influenced the distribution of genetic variations in populations around the world. The study, conducted by a team from the Howard Hughes Medical Institute, the University of Chicago, the University of California and Stanford University, is published June 5 in the open-access journal PLoS Genetics.

In recent years, geneticists have identified a handful of genes that have helped human populations adapt to new environments within just a few thousand yearsa strikingly short timescale in evolutionary terms. However, the team found that for most genes, it can take at least 50,000-100,000 years for natural selection to spread favorable traits through a human population. According to their analysis, gene variants tend to be distributed throughout the world in patterns that reflect ancient population movements and other aspects of population history. "We don't think that selection has been strong enough to completely fine-tune the adaptation of individual human populations to their local environments," says co-author Jonathan Pritchard. "In addition to selection, demographic history -- how populations have moved around -- has exerted a strong effect on the distribution of variants."

To determine whether the frequency of a particular variant resulted from natural selection, Pritchard and his colleagues compared the distribution of variants in parts of the genome that affect the structure and regulation of proteins to the distribution of variants in parts of the genome that do not affect proteins. Since these neutral parts of the genome are less likely to be affected by natural selection, they reasoned that studying variants in these regions should reflect the demographi
'/>"/>

Contact: Catriona Silvey
csilvey@plos.org
Public Library of Science
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mixing genomics and geography yields insights into life and environment
2. Biogeography, changing climates and niche evolution
3. Surprising discovery from first large-scale analysis of biodiversity and biogeography of viruses
4. Prehistoric aesthetics explains snail biogeography puzzle
5. History of hyperactivity off-base, says researcher
6. Penn Medicine honored for its historic role in the history of microbiology
7. Tiny differences in our genes help shed light on the big picture of human history
8. DOE makes largest Danforth Campus research award in history
9. Study of protein structures reveals key events in evolutionary history
10. Chantix side effects no worse with depression history
11. NJIT history professor receives national endowment for humanities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... 09, 2014 Research and Markets , ... ) has announced the addition of the "Biometrics ... offering. One major trend emerging in ... in technology, it is important to upgrade biometric solutions ...
(Date:12/11/2014)... N.C. , Dec. 10, 2014  That blood pressure plays ... a while. Hypertension – the medical term for high blood ... early 1800s, and the inflatable cuff that,s used in measuring ... however, mean there,s nothing new about hypertension, its triggers and ...
(Date:12/10/2014)... here before: you desperately need to sign into your online banking ... to your secret question. What,s your dog,s birthday? Who was your ... a digital infrastructure security company, launches the app that ... usernames, passwords and PINs – 1U TM . 1U ...
Breaking Biology News(10 mins):Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... As natural gas development expands nationwide, policymakers, communities ... impact assessments (HIA) as a means of predicting the ... new study from the Colorado School of Public Health. ... American Journal of Public Health , highlights lessons learned ...
... WHAT: ... Charitable Trusts as the "Biomedical Researcher of the Month," for his ... As a postdoctoral researcher in the Princeton University laboratory of Lynn ... type 1 (HSV-1)which, in rare cases, can lead to blindness or ...
... of the Philosophical Transactions of The Royal Society ... our society: feeding a global population that is simultaneously ... preventing widespread ecological and social impoverishment. According ... Hole Research Center (WHRC) and one of the issue,s ...
Cached Biology News:Health impact assessments prove critical public health tool 2Viral curiosity spreads across continents 2Ecology, economy and management of an agro-industrial Amazon frontier 2Ecology, economy and management of an agro-industrial Amazon frontier 3
(Date:1/22/2015)... 22, 2015 Shimadzu Scientific Instruments ... multipurpose UV-visible spectrophotometer. Offering wavelength scanning from 190 ... ideal for applications in a variety of industries, ... The user-friendly UV-1280 enables intuitive operation, while the ...
(Date:1/22/2015)... NH (PRWEB) January 22, 2015 GEA ... a table top laboratory homogenizer, the PandaPLUS 2000, which ... nanodispersions, nanoemulsions , and cell disruption . This ... dairy products, fruit juices, liquid food, food additives and ...
(Date:1/22/2015)... Cambridge Semantics, the leading provider of smart data solutions ... a record-breaking year across the board for the company. ... Platform and our Smart Data solutions, our customers were able ... led to record growth for the company in 2014,” said ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Protocol Networks ... The growing team of brand-neutral, independent consultants, Protocol Networks ... Rogers explained that over the years, his company has ... Moroso, Town of Plainfield, as well as others. With ...
Breaking Biology Technology:Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Cambridge Semantics Announces Record Results for 2014 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
... Pharmaceuticals, Inc., a privately held drug development company, ... New Drug (IND) application with the U.S. Food ... anticancer compound. GGTI-2418 is a synthetic peptidomimetic ... to induce apoptosis by downregulating several pivotal oncogenic ...
... Advancing Core Lysosomal Storage Disorder Programs to Key Milestones ... 5 Amicus Therapeutics (Nasdaq: FOLD ) ... full year 2008. On a reported basis calculated in ... announced a net loss attributable to common stockholders of ...
... CALGARY, Feb. 5 /PRNewswire-FirstCall/ - Dr. Brad Thompson, President ... ONCY ), will present a corporate overview ... America Conference on Monday, February 9, 2009 at 4:30 ... Westin Bayshore Resort in Vancouver, B.C. from February 8-10, ...
Cached Biology Technology:Tigris Pharmaceuticals Files IND Application for GGTI-2418 2Tigris Pharmaceuticals Files IND Application for GGTI-2418 3Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 2Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 3Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 4Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 5Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 6Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 7Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 8Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 9Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 10Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 11Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 12Amicus Therapeutics Announces Fourth Quarter and Full Year 2008 Financial Results 13Media Advisory - Oncolytics Biotech(R) Inc. to Present at BioPartnering North America 2
... CultureWell cell culture chambered coverslips ... cells for staining and imaging. ... silicone gaskets with standard optical-quality ... and ready to use. Preassembled ...
... mL - 25 mL pipets ,Angled acrylic pipet ... standard square or round pipet cans. Constructed of 6 ... 76 mm W x 76 mm H x 289 ... Overall dimensions: 89 mm W x 406 mm H ...
... CultureWell cell culture systems provide an ... for staining and imaging. Each system ... standard optical-quality coverslips in cell culture ... sterile and ready to use. Individual ...
Request Info...
Biology Products: