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Genomes of 2 popular research strains of E. coli sequenced
Date:10/20/2009

tailed genomic analysis uncovered this long-buried mix-up.

Once this mystery was solved, every difference between the two B genome sequences could be understood in terms of the different laboratory manipulations used on the ancestral strains, Studier said. This information provided new insights into the types of changes to the genome caused by standard laboratory treatments, including exposure to chemicals, irradiation with ultraviolet light, and transfer of DNA between genomes.

"It's amazing how much valuable information can be revealed by looking in detail at genome sequences," Studier said.


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Contact: Kendra Snyder
ksnyder@bnl.gov
631-344-8191
DOE/Brookhaven National Laboratory
Source:Eurekalert

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