Navigation Links
Genomes of 2 popular research strains of E. coli sequenced
Date:10/20/2009

Upton, NY -- An international team of researchers from the United States, Korea, and France has sequenced and analyzed the genomes of two important laboratory strains of E. coli bacteria, one used to study evolution and the other to produce proteins for basic research or practical applications. The findings will help guide future research and will also open a window to a deeper understanding of classical research that is the foundation of our understanding of basic molecular biology and genetics.

The team, which includes two researchers from the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, published its results online on October 17, 2009, in three papers in the Journal of Molecular Biology.

E. coli has been associated with recent outbreaks of food-borne illnesses, but the two most important laboratory types, named K-12 and B, were isolated from benign E. coli that are normal inhabitants of the human intestine. Both have been indispensable tools for biomedical research and biotechnology.

K-12 was isolated in 1922 in Palo Alto, California. Its genome sequence the series of nucleotide bases (labeled A, T, G, and C) that make up the source code for running the machinery of the cell has been known since 1997. The early history of B, however, was unknown until the current collaboration combed through historical scientific papers and personal recollections to trace it back to a strain at the Institut Pasteur, in Paris, in 1918. Adding to this historical reconstruction, the newly sequenced genomes of two different B strains allow the complete genomes of these laboratory workhorses to be compared for the first time.

"Although the B and K-12 strains came into the laboratory half a world apart, their genome sequences show that they are closely related," said Brookhaven biophysicist William Studier, who, along with Brookhaven physicist Sergei Maslov helped analyze the genome sequences.'/>"/>

Contact: Kendra Snyder
ksnyder@bnl.gov
631-344-8191
DOE/Brookhaven National Laboratory
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Genomes reveal bacterial lifestyles: Research
2. After dinosaurs, mammals rise but their genomes get smaller
3. New computational technique allows comparison of whole genomes as easily as whole books
4. Cold Spring Harbor Protocols features methods for analyzing genomes and plant cells
5. Cold Spring Harbor Protocols features methods to screen genomes and analyze evolution
6. Latest Integrated Microbial Genomes data management system update release
7. Scientists decode genomes of diverse TB isolates
8. International team compares 12 fruit fly genomes
9. Study: Popular supplement quercetin does not enhance athletic performance
10. Quality and purity of popular stevia sweetener strengthened by new reference standards
11. New standard for popular stevia-based sweetener to assure products quality
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/29/2014)... the international Cancer Genomics of the Kidney consortium ... kidney cancer and exposure to aristolochic acid, an ... in Nature Communications , have important implications ... than 140,000 people every year, and in Central ... part of the International Cancer Genome Consortium (ICGC), ...
(Date:10/28/2014)... of the tragic realities of cancer is that ... toxic and their effectiveness varies unpredictably from patient ... poised to change this reality by rapidly assessing ... an individual,s cancer before chemotherapy begins. , A ... by Assistant Professor Melissa Skala has developed the ...
(Date:10/28/2014)... Scientists from North America, Europe and China have published ... Academy of Sciences that reveals important details about ... our planet., From strange and exotic algae, mosses, ferns, ... the grains and vegetables we eat and the ornamental ... shares over a billion years of history., "Our study ...
Breaking Biology News(10 mins):Kidney cancer in Central Europe 2Improving breast cancer chemo by testing patient's tumors in a dish 2Improving breast cancer chemo by testing patient's tumors in a dish 3New study uses DNA sequences to look back in time at key events in plant evolution 2New study uses DNA sequences to look back in time at key events in plant evolution 3
... shows that birds may choose their mate with the help ... their young a more efficient immune system. This has been ... in Sweden, in a Swedish-French collaboration. Humans and many ... mate with the right smell can give the offspring an ...
... why autism spectrum disorders are almost five times more common ... to a five-year, $15 million National Institutes of Health (NIH) ... Centers of Excellence (ACE) research program. Led by ... Yale ACE award is part of a $100 million National ...
... - Influenza outbreaks in the United States typically begin ... spread in seasonal waves across geographic zones. But the ... to the next has baffled scientists. In a ... Obscure Consequence," Elena Naumova, Ph.D., professor of civil and ...
Cached Biology News:Influenza research: Can dynamic mapping reveal clues about seasonality? 2
(Date:10/27/2014)... 2014 Ryan Carfley , Managing Partner ... sit down with Bryan Hamilton, the publisher of the Triangle ... talent in the Research Triangle region of North Carolina. , ... at the roundtable include the role of social media ... work/life balance and the unique role that Millennials play in ...
(Date:10/27/2014)... Oct. 27, 2014 Kalorama Information says that ... concern in the United States ... healthcare market researcher said the FDA,s Emergency Use Authorization (EUA) ... tests for the detection of the Ebola virus was ... Kalorama routinely assess the IVD industry and its biennial ...
(Date:10/27/2014)... The report “Smart Highway Market by Technology ... and by Display (Variable Message Signs, Digital Signage) ... market into various sub-segments with in-depth analysis and ... and restraints for this market with insights into ... tables and 37 figures spread through 141 pages ...
(Date:10/26/2014)... October 26, 2014 The report ... ADC, Network Security Equipment, WAN Optimization Appliances]: Global ... segments the data center networking market into various ... revenues. The report also identifies the factors driving ... impacting it along with the future roadmaps. , ...
Breaking Biology Technology:Personify's Ryan Carfley Talks Recruiting with Triangle Business Journal, RPG Solutions 2Personify's Ryan Carfley Talks Recruiting with Triangle Business Journal, RPG Solutions 3Kalorama: PCR The Go-to Test in Ebola Fight 2Kalorama: PCR The Go-to Test in Ebola Fight 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 2Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 4Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 2Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 3Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 4
... Aaron Mitchell, managing principal at global management consulting firm ... of 2011 by Consulting Magazine. Mitchell was recognized for directing ... several years and during a major, recent product launch. ... top consultants," said Mitchell, who has more than 10 years ...
... 1, 2011 Reportlinker.com announces that a ... its catalogue: Biochips and ... http://www.reportlinker.com/p0350354/Biochips-and-Microarrays---Technologiesmarkets-and-companies.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Genomics This ... based on technologies and applications. The report ...
... Reportlinker.com announces that a new market ... Osteosarcoma Therapeutics - Pipeline ... http://www.reportlinker.com/p0546797/Osteosarcoma-Therapeutics---Pipeline-Assessment-and-Market-Forecasts-to-2017.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Pathology ... Forecasts to 2017 Summary ...
Cached Biology Technology:Managing Principal at ZS Associates Named One of Consulting Magazine's Top 25 Consultants of 2011 2Reportlinker Adds Biochips and Microarrays - Technologies, markets and companies 2Reportlinker Adds Biochips and Microarrays - Technologies, markets and companies 3Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 2Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 3Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 4Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 5Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 6Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 7Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 8Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 9Reportlinker Adds Osteosarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017 10
ERalpha (Ser 104/106)...
... Phosphatase, Calf Intestinal (CIAP), catalyzes the hydrolysis ... ribo- and deoxyribonucleoside triphosphates. This enzyme is ... linearized cloning vector DNA by removing phosphate ... be used for the dephosphorylation of 5 ...
Mouse CXCR3 Allophycocyanin MAb (Clone 220803)...
Homo sapiens palladin...
Biology Products: