Navigation Links
Genome-wide imaging study identifies new gene associated with Alzheimer's plaques
Date:2/20/2013

the brain, the researchers conducted PET scans of 555 participants in the Alzheimer's Disease Neuroimaging Initiative, a long-term public-private research project that includes people at risk for Alzheimer's disease and patients who have been diagnosed with the disease as well as participants with no symptoms.

With sophisticated statistical analyses, the imaging data was combined with analyses of DNA collected from the 555 participants to determine whether particular gene variants were found more often among patients with higher levels of plaque deposits.

The analysis found that a variant in BCHE was significantly associated with the levels of plaque deposits. As would be expected, the analysis also found a strong association with variants of another gene, APOE, that has long been known to be associated with the development of Alzheimer's. The effect of BCHE was independent of APOE, however. Moreover, the effects of the two genes were additive -- that is, people with the suspect variants of both genes had more plaque deposits than people who had only one of the variants associated with plaque development


'/>"/>

Contact: Eric Schoch
eschoch@iu.edu
317-274-8205
Indiana University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. In the blink of an eye: X-ray imaging on the attosecond timescale
2. Elsevier announces the launch of a new journal: Journal of Forensic Radiology and Imaging
3. UT Arlington bioengineer to use hybrid imaging system to see deep tissue
4. Improved X-ray microscopic imaging
5. New modeling approach transforms imaging technologies
6. Imaging biomarker predicts response to rapid antidepressant
7. Improving the development of new cancer models using an advanced biomedical imaging method
8. Lyncean Technologies Inc. sells Compact Light Source to Munich biomedical-imaging research center
9. Ocean Thin Films Announces Multispectral Imaging Research Grant Program
10. NREL researchers use imaging technologies to solve puzzle of plant architecture
11. 3dMD Transitions Anatomical Research from 3D-Static to 4D-Movement Surface Imaging
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genome-wide imaging study identifies new gene associated with Alzheimer's plaques
(Date:10/16/2014)... conventional thinking on how the bowel lining develops and, ... bowel cancer starts. , The researchers produced evidence that ... ,crypts, that are a feature of the bowel lining, ... cancer development, a controversial finding as scientists are still ... imaging technologies, Dr Chin Wee Tan and Professor Tony ...
(Date:10/16/2014)... 2014) – Post-menopausal women experienced improvements in vaginal ... or genital bleeding, after 12 weeks of daily ... soy germ-based nutritional supplement previously shown to help ... peer-reviewed pilot study reported in a poster at ... meeting. , "These data documented improved vaginal ...
(Date:10/15/2014)... from strains of influenza virus increases with the latest ... complacent that the most substantial threats have been identified, ... arise when a new virus strain – against which ... in the human population. There have been five such ... which – the 1918 Spanish Flu – cost 50 ...
Breaking Biology News(10 mins):Cryptic clues drive new theory of bowel cancer development 2S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2
... is your goal, you can't do better than to emulate ... and an unusual pitching stroke that allows the bug to ... is a marvel of engineering. , Z. Jane Wang, professor ... research on flying systems and fluid dynamics today (Feb. 19) ...
... at The Zucker Hillside Hospital campus of The ... of a gene that appears to influence intelligence. ... Center for Genetics and Genomics in Boston, the ... individuals with schizophrenia, a neuropsychiatric disorder characterized by ...
... scientists and doctors with the Physicians Committee for Responsible ... grow live cells in the laboratory. At issue is ... by puncturing the heart of a fetal calf without ... in a medium free of animal serum, enabling scientists ...
Cached Biology News:Scientist uses dragonflies to better understand flight 2Feinstein researchers identify intelligence gene 2
(Date:10/22/2014)... 21, 2014 Shimadzu Scientific Instruments introduces ... tool for the pain management and clinical markets. The ... and review by allowing users to highlight and review ... , QuantAnalytics allows analysts to filter results by group ... processing by eliminating the need to sift through analytes ...
(Date:10/22/2014)... 2014 Grace Century, a private equity ... announces the addition of Dr. Yousef “Josh” Siddiqui ... team. Dr. Siddiqui will provide further healthcare expertise to ... of University College Medical School in the ... in 2001. With further certification as a General Practitioner ...
(Date:10/22/2014)... 22, 2014 /PRNewswire/ - iCo Therapeutics ("iCo" or "the ... steps for its Oral Amphotericin B program.  The ... in vitro work involving samples from HIV/AIDS ... to complete pre clinical studies and regulatory filings ... clinical trial, utilizing approximately $700,000 of funding and ...
(Date:10/20/2014)... 20, 2014 The report “Pharmacy ... Systems, Packaging and Labeling Systems, Table-top Counters) by ... Global Forecasts & Trends to 2019” analyzes and ... in North America, Europe, Asia-Pacific, and the Rest ... tables and 30 figures spread through 300 pages ...
Breaking Biology Technology:Shimadzu Releases QuantAnalytics Open Access LCMS Software Package for Clinical Applications 2Dr. Yousef Siddiqui joins the Grace Century Advisory Team 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 2Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 4
... Many biopharmaceuticals comprise small proteins that are quickly eliminated ... (TUM) combine such small proteins with a kind of ... of the proteins in the body. The TUM spin-off ... new technology with blockbuster potential. People who suffer ...
... The Center for Business Intelligence (CBI) announced today that ... Alzheimer,s Drug Development Summit to the Alzheimer,s Association. CBI will ... 2009, in recognition of World Alzheimer,s Day. , , ... raise awareness and encourage citizens to take action against the ...
... NEW YORK, Sept. 21 Emissary Capital Group, Inc. ... Bulletin Board: SNBP) with a Buy rating and target ... as Dong Ying Pharmaceutical Co. Ltd., is a fully ... manufacture and distribution of biopharmaceutical products. The company ...
Cached Biology Technology:Researchers prolong the plasma half-life of biopharmaceutical proteins 2Alzheimer's Drug Development Summit: CBI to Donate Portion of This Week's Proceeds to the Alzheimer's Association 2Alzheimer's Drug Development Summit: CBI to Donate Portion of This Week's Proceeds to the Alzheimer's Association 3Emissary Capital Group Initiates Coverage on Sinobiopharma 2
...
... is the first fully genetically encoded fluorescent ... intracellular hydrogen peroxide (H2O2), one of the ... the basis of yellow fluorescent protein inserted ... protein OxyR (OxyR-RD), HyPer demonstrates submicromolar affinity ...
Alexa Fluor 647 anti-mouse Qa-2...
... essential for hunting and analyzing the ... as EST sequencing projects, microarrays, functional ... is developed for normalization of cDNA ... for directional cloning. While most normalization ...
Biology Products: