Navigation Links
Genome-wide imaging study identifies new gene associated with Alzheimer's plaques
Date:2/20/2013

the brain, the researchers conducted PET scans of 555 participants in the Alzheimer's Disease Neuroimaging Initiative, a long-term public-private research project that includes people at risk for Alzheimer's disease and patients who have been diagnosed with the disease as well as participants with no symptoms.

With sophisticated statistical analyses, the imaging data was combined with analyses of DNA collected from the 555 participants to determine whether particular gene variants were found more often among patients with higher levels of plaque deposits.

The analysis found that a variant in BCHE was significantly associated with the levels of plaque deposits. As would be expected, the analysis also found a strong association with variants of another gene, APOE, that has long been known to be associated with the development of Alzheimer's. The effect of BCHE was independent of APOE, however. Moreover, the effects of the two genes were additive -- that is, people with the suspect variants of both genes had more plaque deposits than people who had only one of the variants associated with plaque development


'/>"/>

Contact: Eric Schoch
eschoch@iu.edu
317-274-8205
Indiana University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. In the blink of an eye: X-ray imaging on the attosecond timescale
2. Elsevier announces the launch of a new journal: Journal of Forensic Radiology and Imaging
3. UT Arlington bioengineer to use hybrid imaging system to see deep tissue
4. Improved X-ray microscopic imaging
5. New modeling approach transforms imaging technologies
6. Imaging biomarker predicts response to rapid antidepressant
7. Improving the development of new cancer models using an advanced biomedical imaging method
8. Lyncean Technologies Inc. sells Compact Light Source to Munich biomedical-imaging research center
9. Ocean Thin Films Announces Multispectral Imaging Research Grant Program
10. NREL researchers use imaging technologies to solve puzzle of plant architecture
11. 3dMD Transitions Anatomical Research from 3D-Static to 4D-Movement Surface Imaging
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genome-wide imaging study identifies new gene associated with Alzheimer's plaques
(Date:7/9/2014)... be able to cope with the rising salinity of Arctic ... today is best known for its tundra and polar bear ... 38 million years ago during what is known as the ... temperate forest with brackish water, home to a variety of ... giant tortoises. Much of what is known about the region ...
(Date:7/9/2014)... be on the verge of an economy driven by methane, ... coal and is undergoing a production boom. It has poised ... research is casting serious doubts over just how climate-friendly it ... News (C&EN), the weekly news magazine of the American ... correspondent at C&EN, explains that when burned as a fuel ...
(Date:7/9/2014)... Cholinergic inhibitors and N-methyl-D-aspartate receptor antagonists can ... fail to affect irreversible cognitive dysfunction and ... brain. Amyloid beta peptide (Aβ) vaccines reduced ... disease (AD) transgenic mouse model, and significantly ... Cao and his team, First Affiliated Hospital ...
Breaking Biology News(10 mins):Shark teeth analysis provides detailed new look at Arctic climate change 2Shark teeth analysis provides detailed new look at Arctic climate change 3
... the frontal cortex in adults, researchers have shown that this ... actions. , It has been known for over 100 ... left frontal cortex, he or she often suffers difficulties in ... impairments, it has been difficult for researchers to test the ...
... high levels of antibodies against the Epstein-Barr virus, the ... likely to develop multiple sclerosis 15 to 20 years ... will appear in the June 2006 print issue of ... Researchers have long suspected that external factors may influence ...
... The cholesterol-lowering medications called statins do not appear to ... to a meta-analysis of previous studies in the January ... that statins reduce the risk of developing cancer, the ... "Statins have been studied in numerous large-scale, randomized, ...
Cached Biology News:Big hips, big belly? It's in your genes, Joslin-led study shows 2Statins have neutral effect on risk of cancer 2
(Date:1/15/2014)... device," Nobel laureate Herbert Kroemer famously observed, referring ... the junctures where layers of different materials meet. ... between layers of metal oxides are becoming increasingly ... spintronics, high-temperature superconductors, ferroelectrics and multiferroics. Realizing the ...
(Date:1/15/2014)... Jan. 15, 2014   Niagara Thermal Products is ... Buffalo BioBlower Technologies LLC ("B3") as the critical thermal ... award from the Army Corps of Engineers.  B3 has ... all biological contaminants and destroys VOCs and other chemical ...
(Date:1/15/2014)... SAN JOSE, California , January 15, 2014 ... for cancer, today announced the appointment of Thomas C Reynolds ... over 20 years, development experience gained in the biotechnology industry, ... "I am delighted to welcome Tom at this transformative ...
(Date:1/15/2014)... A study has been launched to test whether ... could help to tackle the problem of obesity.  This unique ... surgery based in Stowmarket) and academics at University Campus Suffolk ... technology, which is inspired by equipment used to collect data ...
Breaking Biology Technology:A deeper look at interfaces 2Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4
... 19, 2011 OptiScan Biomedical Corporation, a developer ... in intensive care units (ICU), today announced that ... has received CE Mark certification for use in ... the OptiScanner has met all relevant European Union ...
... The ALS Therapy Development Institute (ALS TDI) and ... their current research collaboration agreement to test additional ... stop the progression of Amyotrophic Lateral Sclerosis (ALS, ... collaboration is based on encouraging results from early-stage ...
... LA JOLLA, CA September 15, 2011 Researchers at ... which certain viruses such as influenza trigger a type of ... This severe immune reactioncalled a "cytokine storm"floods the tiny ... blocking off airways and damaging body tissues and organs. Cytokine ...
Cached Biology Technology:OptiScan Biomedical Receives CE Mark for OptiScanner Automatic Bedside Glucose Monitoring System 2OptiScan Biomedical Receives CE Mark for OptiScanner Automatic Bedside Glucose Monitoring System 3OptiScan Biomedical Receives CE Mark for OptiScanner Automatic Bedside Glucose Monitoring System 4ALS Therapy Development Institute and Aestus Therapeutics, Inc., Expand Collaboration on Development of Novel ALS Therapies 2ALS Therapy Development Institute and Aestus Therapeutics, Inc., Expand Collaboration on Development of Novel ALS Therapies 3Scripps Research team discovers treatable mechanism responsible for often deadly response to flu 2Scripps Research team discovers treatable mechanism responsible for often deadly response to flu 3
... The IHC Select Immunophosphatase Secondary Detection System ... IHC Select Prediluted Primary Antibody reagents, which ... qualitative identification of antigens by light microscopy ... Secondary Detection System may also be used ...
... FLISP Assay with SR-101 Labeled Substrates ... • Accurately measure serine protease activation ... • B-Bridge's FLISP Kits utilize cell-permeable, ... (FLISPs) to measure chymotrypsin-like activity in ...
From the company that first brought you the chromatin immunoprecipitation (ChIP) kit, a new and improved kit, EZ-ChIP, is now available to make your experiments easier, quicker, and most importantly,...
The PDS-1000 He Hepta system includes the PDS-1000 He biolistic system and the Hepta adaptor....
Biology Products: