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Genome of simplest animal reveals ancient lineage, confounding array of complex capabilities
Date:8/22/2008

rons have ever been reported," explained Rokhsar.

Of the 11,514 genes identified in the six chromosomes of Trichoplax, 80 percent are shared with cnidarians and bilaterians. Trichoplax also shares over 80 percent of its intronsthe regions within genes that are not translated into proteinswith humans. Even the arrangement of genes is conserved between the Trichoplax and human genomes. This stands in contrast to other model systems such as fruit flies and soil nematodes that have experienced a paring down of non-coding regions and a loss of the ancestral genome organizations.

With its pancake shape, gutless feeding, and genomic primitiveness, the rich array of metabolic capabilities begs additional consideration. While it has been observed to motor around via cilia, eat by mounting its prey, and reproduce by fission (pulling itself into pieces)it may in fact have a secret sex life.

"Some of our new placozoan species show frequent sexual reproduction while others never show any signs of sex," said Schierwater. "The genome data allow us to search for the genes responsible for sex and life cycle complexity."

"It's remarkable that we have the whole genome sequence but we still know so little about this animal in the wild," said Rokhsar. "Hopefully the genome sequence will stimulate more studies of this enigmatic creature."


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Contact: David Gilbert
degilbert@lbl.gov
925-296-5643
DOE/Joint Genome Institute
Source:Eurekalert  

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