Navigation Links
Genome 10K Project announces first 101 species for genome sequencing
Date:11/30/2010

SANTA CRUZ, CA--The Genome 10K Community of Scientists and BGI (formerly the Beijing Genomics Institute) of Shenzhen, China, have announced a plan to sequence the genomes of 101 vertebrate species within the next two years, the first of an eventual 10,000 species to be sequenced by the Genome 10K Project.

The Genome 10K Project (G10K) is an international effort to gather specimens of thousands of animals from zoos, museums, and university collections throughout the world, and then sequence the genome of each species to reveal its complete genetic heritage. The project aims to assemble a genomic zoo--a collection of DNA sequences for 10,000 vertebrate species (approximately one for every vertebrate genus) by 2015.

Genome 10K cofounder David Haussler, a professor of biomolecular engineering in the Baskin School of Engineering at UC Santa Cruz, said the first 101 species to be sequenced were selected from the Genome 10K database, which catalogs specimens suitable for sequencing from more than 16,000 vertebrate species, both living and recently extinct. (A list of the selected species is available for download.)

"These genomes will provide a new and exciting window into vertebrate biology," Haussler said. "The experiments of evolution represented in them carry critical information about how animals are built and how they function at the molecular level."

The planned sequencing will take place within the next 24 months at the BGI facilities in China. BGI has recently amassed the largest number of advanced DNA sequencing machines under one roof of any institute in the world and is committed to large-scale application of genome sequencing in science and medicine.

"With this joint pledge to accomplish whole-genome sequence assembly and annotation of 101 new vertebrate species--the first 1 percent of the Genome 10K target--we move much closer to providing students of biology the unabridged DNA code book for the wonder of living vertebrate forms," said project cofounder Stephen J. O'Brien, chief of the Laboratory of Genomic Diversity at the National Cancer Institute.

The sequencing project builds on a BGI project launched in January 2010, called the 1,000 Plant and Animal Reference Genome Project. According to BGI executive director Jun Wang, their project harnesses the leading sequencing platform, advanced technologies, and powerful bioinformatics analytical capability.

"The collaboration with G10K will not only significantly facilitate the progression of BGI's genomics research, but also benefit the development of global genomics researches and their relevant industrial application," Wang said.

The 101 vertebrate species chosen for this phase of the project were selected by a consortium of BGI scientists, their collaborators, sponsors, and the chairs of the Genome 10K taxonomy groups for mammals, birds, amphibians, reptiles, and fish. The species were chosen to capture phylogenetic diversity across the vertebrate radiations while avoiding overlap with public-sponsored whole-genome sequencing projects. Other considerations included the biological features that make a species interesting to humankind, the science community around each species, and the availability of vouchered specimens.

According to Genome 10K cofounder Oliver Ryder, director of genetics at the San Diego Zoo Institute for Conservation Research, the collection and banking of samples in international centers, such as San Diego's Frozen Zoo, sets the stage for rapid progress toward the sequencing goals in collaboration with major sequencing centers, such as BGI. "The data produced provide a major contribution to understanding aspects of the biology of many endangered species, thereby assisting in conservation efforts on their behalf," Ryder said.

In addition to the 101 species chosen for G10K, there are 120 vertebrate species already being sequenced in public-sector genome projects (download list here). The completion of 221 whole-genome sequences within a few years is a first step toward the G10K goal of obtaining high-quality whole-genome sequences, assembled and annotated, for 10,000 vertebrate species. To meet the quality goals of the G10K project, every species must have a reference genome sequence with chromosome-scale contiguity suitable for display on a genome browser and accurate enough for genome-based research.

Selection of future species for sequencing in the Genome 10K project will involve open-science-based input and collaboration, Haussler said. Haussler's team at UCSC's Center for Biomolecular Science and Engineering maintains the Genome 10K database and the UCSC Genome Browser.

The Genome 10K Project will hold a workshop in Santa Cruz, California, from March 14 to 18, 2011. This workshop will accomplish two goals: First, it will continue the mission to gather biological specimens of vertebrate species and describe them thoroughly on a public database. Second, it will gather genome assembly experts to develop a robust solution to the challenge of creating useful assembly with short reads and combined-scaffold assembly approaches.


'/>"/>

Contact: Tim Stephens
stephens@ucsc.edu
831-459-2495
University of California - Santa Cruz
Source:Eurekalert

Related biology news :

1. MU plant genome research receives $3 million boost from National Science Foundation
2. ASPB members lead new plant genome research program awards
3. Is the shape of a genome as important as its content?
4. NSF awards new projects for plant genome research
5. NSF awards $3.75 million grant to New York Plant Genome Consortium for the creation of BigPlant v1.0
6. NIH-funded scientists sequence genomes of lyme disease bacteria
7. Singapore scientists first to perform genome-wide study of human stem cells
8. UBC gains $5.4 million for microbiome research from CIHR, Genome BC
9. UF to help sequence genome of flowering plants ancient living relative
10. Genome inversion gives plant a new lifestyle
11. Genomic haircut makes worlds tiniest genome even smaller: UBC research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... 2016 Paris Police Prefecture ... security solution to ensure the safety of people and operations ... the major tournament Teleste, an international technology group ... announced today that its video security solution will be utilised ... up public safety across the country. The system roll-out is ...
(Date:6/2/2016)... June 2, 2016 The Department of ... awarded the 44 million US Dollar project, for the ... Plates including Personalization, Enrolment, and IT Infrastructure , ... the production and implementation of Identity Management Solutions. Numerous renowned ... Decatur was selected for the most ...
(Date:6/1/2016)... NEW YORK , June 1, 2016 ... Biometric Technology in Election Administration and Criminal Identification to ... According to a recently released TechSci Research report, " ... Sector, By Region, Competition Forecast and Opportunities, 2011 - ... $ 24.8 billion by 2021, on account of growing ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... - FACIT has announced the creation of a ... Propellon Therapeutics Inc. ("Propellon" or "the Company"), to ... of first-in-class WDR5 inhibitors for the treatment of ... an exciting class of therapies, possessing the potential ... patients. Substantial advances have been achieved with the ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
(Date:6/23/2016)... Ky. , June 23, 2016 ... two Phase 1 clinical trials of its complement ... placebo-controlled, single and multiple ascending dose studies designed ... pharmacodynamics (PD) of subcutaneous injection in healthy adult ... subcutaneously (SC) either as a single dose (ranging ...
(Date:6/23/2016)... ... June 23, 2016 , ... Regulatory ... technical consulting, provides a free webinar on Performing Quality Investigations: Getting ... at 12pm CT at no charge. , Incomplete investigations are still a major ...
Breaking Biology Technology: