Navigation Links
Genomatix, USU and HJF execute a CRADA: Prostate cancer prognostic marker discovery by NGS
Date:8/22/2011

Genomatix Software, the Uniformed Service University of the Health Sciences (USU), and the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) have entered into a Cooperative Research and Development Agreement (CRADA) to extend their collaborative endeavors in prostate disease research. The aim of the joint research will be to differentiate patients with favorable versus poor prognosis at the time of diagnosis and primary treatment using definitive genetic markers. The majority of prostate cancer cases in PSA-screened population fall into a so called "grey zone" of prostate cancer where outcome is extremely difficult to predict at the time of diagnosis. The CRADA extends a long and already fruitful collaboration (Masuda, Werner et al, J Mol Biol. 353, 763-771 2005; Furusato et al, PCPD. 11, 194-97, 2008) with USU's Center for Prostrate Disease Research (CPDR). This collaboration combines CPDR's translational research resources and expertise and Genomatix' data analysis expertise in teasing out novel androgen receptor binding sites in the genome and analyzing prostate cancer metastasis using prostate cancer model systems and clinical specimens.

"This CRADA is a natural extension of accomplishments we have already achieved together," said Dr. Thomas Werner, founder of Genomatix Software. "Next Generation Sequencing opens a new dimension in biomarker research and will allow a finer grained, unbiased look at some of the genomic mechanisms behind prostate disease, thus providing the opportunity for the discovery of new prognostic biomarkers, some of which also may be targets for therapeutic intervention and treatment monitoring."

Dr. Shiv Srivastava; CPDR Co-director, Scientific Director, and Professor of Surgery at USU added: "Our work to date with Genomatix has been very productive. People from both our organizations have already established quality working relationships. Leveraging this and moving forward together into a technology as ground breaking as Next Generation Sequencing holds great promise for significant progress in prostate disease research."


'/>"/>

Contact: Korbinian Grote
grote@genomatix.de
Genomatix Software GmbH
Source:Eurekalert

Related biology news :

1. Genetic risk factors may tailor prostate cancer screening approaches
2. Prostate cancer spurs new nerves
3. Men with wives, significant others more likely to be screened for prostate cancer
4. New lab evidence suggests preventive effect of herbal supplement in prostate cancer
5. Dana-Farber oncologists present at ASCO GU -- predict prostate cancer survival using Source MDx test
6. Freezing prostate cancer does a mans body good
7. New medications show promise in treating drug-resistant prostate cancer
8. New drug shows promise in treating drug-resistant prostate cancer
9. Agent Orange exposure increases veterans risk of aggressive recurrence of prostate cancer
10. 3-D research model tackles prostate cancer spread
11. Gene activity reveals dynamic stroma microenvironment in prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... Calif. , April 13, 2017 UBM,s ... York will feature emerging and evolving technology ... Both Innovation Summits will run alongside the expo portion ... speaker sessions, panels and demonstrations focused on trending topics ... largest advanced design and manufacturing event will take place ...
(Date:4/11/2017)... 11, 2017 Crossmatch®, a globally-recognized leader ... today announced that it has been awarded a ... Activity (IARPA) to develop next-generation Presentation Attack Detection ... "Innovation has been a driving force within Crossmatch ... allow us to innovate and develop new technologies ...
(Date:4/11/2017)... 11, 2017 No two people are ... the New York University Tandon School of Engineering ... found that partial similarities between prints are common ... mobile phones and other electronic devices can be ... vulnerability lies in the fact that fingerprint-based authentication ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... Lithuania, announced today that they have entered into a multiyear collaboration to identify ... CRISPR researchers with additional tools for gene editing across all applications. , Under ...
(Date:10/12/2017)... ... October 12, 2017 , ... AMRI, ... and biotechnology industries to improve patient outcomes and quality of life, will now ... testing are being attributed to new regulatory requirements for all new drug products, ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... in its endogenous context, enabling overexpression experiments and avoiding the use of exogenous ... RNA guides is transformative for performing systematic gain-of-function studies. , This complement ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... today it will be hosting a Webinar titled, “Pathology is going digital. Is ... , on digital pathology adoption best practices and how Proscia improves lab economics ...
Breaking Biology Technology: