Navigation Links
Genetics study reveals how bacteria behind serious childhood disease evolve to evade vaccines
Date:1/29/2012

ffect was a mixture of a large drop in frequency of the serotypes targeted by the vaccine with some growth in serotypes not targeted by the vaccine. The 13-valent vaccine was introduced in the UK in 2010.

Derrick Crook, Professor of Microbiology at the University of Oxford and Infection Control Doctor at the Oxford University Hospitals NHS Trust, adds: "Childhood vaccines are very effective at reducing disease and death at a stage in our lives when we are susceptible to serious infections. Understanding what makes a vaccine successful and what can cause it to fail is important. We should now be able to understand better what happens when a pneumococcal vaccine is introduced into a new population. Our work suggests that current strategies for developing new vaccines are largely effective but may not have long term effects that are as successful as hoped."

Dr Bernard Beall, a scientist at the Centers for Disease Control and Prevention commented: "The current vaccine strategy of targeting predominant pneumococcal serotypes is extremely effective, however our observations indicate that the organism will continue to adapt to this strategy with some measurable success."

The Wellcome Trust, which part-funded this research, views combating infectious disease and maximising the health benefits of genetic research as two of its strategic priorities. Dr Michael Dunn, Head of Molecular and Physiological Sciences at the Wellcome Trust commented: "New technologies allow us to rapidly sequence disease-causing organisms and see how they evolve. Coupled with collaborations with epidemiologists, we can then track how they spread and monitor the potential impact this will have on vaccine efficiency. This will provide useful lessons for vaccine implementation strategies."


'/>"/>

Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Ambry Genetics Reports Results from Clinical Diagnostic Exomeâ„¢ Testing of Three Patients
2. The power of flowers: Research sprouts a closer look at sunflower genetics
3. New international Ph.D. program on Dynamics of Gene Regulation, Epigenetics and DNA Damage Response
4. Evolution at warp speed: Hatcheries change salmon genetics after a single generation
5. Genetics professor Jonathan Arnold named AAAS Fellow
6. YeastBook, the Eukaryotic Cell Encyclopedia is launched by Genetics
7. Fish flu: Genetics approach may lead to treatment
8. Modern genetics answers age-old question on Garrods fourth inborn error of metabolism
9. Einstein College of Medicine given $6.7 million to study congenital heart defect genetics
10. New discoveries in genetics of lung health
11. Genetics meets metabolomics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... N.C. , Dec. 9, 2014  Valencell, a ... it is seeing a staggering demand from its licensees ... the Company revealed, is not solely coming from fitness ... as well. "A wearable is only as ... result, accuracy is the ultimate driver in long-term mass ...
(Date:12/10/2014)... SAN DIEGO , Dec. 9, 2014 ... and collaboration catalyst that provides the connective tissue that ... by enabling them to easily share client-level information; earned ... Foundation to expand to organizations serving seniors aging in ... San Diego" partner on December 11 th 4-6p. ...
(Date:12/10/2014)... 9, 2014     ...   Jifflenow, a ... solutions for business-to-business (B2B) events, today announced a ... mobile near-field communication (NFC), Bluetooth low energy (BLE), ... http://photos.prnewswire.com/prnh/20140612/691055) , Jifflenow will integrate its ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
... University,s work in protecting the lives and livelihoods of some ... prestigious national award. At the Times Higher Education awards ... the School of Planning, Architecture and Civil Engineering received the ... award recognises the team,s work in tackling the world,s worst ...
... the University of Leicester have identified for the first time ... of sugar in our blood following a meal. ... in helping to maintain correct blood sugar levels. The ... team led by Professor Andrew Tobin, Professor of Cell Biology, ...
... Universitaet Muenchen (TUM) have formed a strategic alliance for catalysis ... field of catalysis, a major aspect of this cooperation will ... to help meet the rising global demand for energy and ... this research work with up to two million euros a ...
Cached Biology News:Queen's life-saving research wins education 'Oscar' 2Up to 20 million euros for Munich Catalysis research cooperation 2Up to 20 million euros for Munich Catalysis research cooperation 3
(Date:12/22/2014)... , Dec. 22, 2014  Alternative Energy ... that it has signed a letter of intent ... has developed and patented a nanotechnology-based development platform ... products that enable rapid on-site collection and testing ... and health issues in an immediate, non-invasive and ...
(Date:12/22/2014)... Chicago, Illinois (PRWEB) December 22, 2014 ... representing tenants and occupiers of commercial real estate, has ... two new offices in Perth and Brisbane, Western Australia, ... board of directors. , ITRA Global / ACORPP ... and totally independent consultancy company providing property services to ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one of ... Nick Maroulis, Pharm.D. to the newly created position of ... this position, Dr. Maroulis will continue to manage the ... our multi-site pharmacies as the company expands. Dr. Maroulis ... time he has served in many different capacities in ...
(Date:12/19/2014)... , Dec. 19, 2014 Decision Resources Group ... grow at a 12 percent compound annual growth rate ... the aging population and the increasing adoption of dental ... will also spur demand for dental biomaterials ... implant and periodontal treatments. Other key findings ...
Breaking Biology Technology:ALNE Announces Intention To Acquire BioTechPharma 2ITRA Global Continues International Expansion in Perth and Brisbane, Australia 2BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 2Latin American Dental Biomaterial Market Will Expand at a 12 Percent Annual Growth Rate Through 2023 3
... Jazz,Pharmaceuticals, Inc. (Nasdaq: JAZZ ) today announced ... on Tuesday, November 6, 2007,following the close of the ... call and live audio webcast to discuss the,quarterly results ... p.m.,Eastern Time/2:00 p.m. Pacific Time. The live webcast ...
... Oct. 24 /PRNewswire-FirstCall/ - Atrium Innovations Inc. (TSX:,ATB) ... at 10 a.m. Eastern,time on November 8, 2007. ... 2007 third quarter results issued earlier the previous ... following numbers:,416-644-3418, 514-807-8791 or 800-591-7539 or via the ...
... IRVINE, Calif., Oct. 24 Cardiogenesis,Corporation (OTC: CGCP), ... third quarter ended September 30, 2007 prior to ... also said that President Richard,P. Lanigan and Senior ... will host an investor conference call that day ...
Cached Biology Technology:Jazz Pharmaceuticals, Inc. to Announce Third Quarter 2007 Financial Results on November 6, 2007 2Atrium Innovations to Hold 2007 Third Quarter Financial Results Conference Call and Webcast on November 8 2Cardiogenesis Corporation to Report Third Quarter 2007 Results on November 14th 2
... Butcher (1998). • The major histocompatibility complex ... the immunology area. There is great interest ... in their function as antigen-presenting molecules. Many ... prospect of tackling biochemical and genetic techniques ...
actin from rabbit muscle Cell Biology Cytoskeletal Probes Actin and Actin Probes...
... 71-18 mutS and ES1301 mutS are mismatch ... of these strains prevents repair of the ... high mutation efficiencies and making them helpful ... Altered Sites II Mutagenesis Systems. Both ES1301 ...
propidium iodide *1.0 mg/mL solution in water*...
Biology Products: