Bethesda, MDApril 30, 2013 Listed below are the selected highlights for the May 2013 issue of the Genetics Society of America's journal, GENETICS. The May issue is available online at http://www.genetics.org/content/current. Please credit GENETICS, Vol. 194, MAY 2013, Copyright 2013.
Please feel free to forward to colleagues who may be interested in these articles on a wide array of topics including: developmental and behavioral genetics; genome integrity and transmission; genetics of complex traits; cellular genetics; and population and evolutionary genetics.
Developmental and Behavioral Genetics
An organelle gatekeeper function for Caenorhabditis elegans UNC-16 (JIP3) at the axon initial segment, pp. 143-161
S. L. Edwards, S.-c. Yu, C. M. Hoover, B. C. Phillips, J. E. Richmond, and K. G. Miller
Nerve cell bodies have a vastly different organelle composition than axons. This article (see accompanying commentary by Zheng and Nonet, pp. 35-37) provides insight into the basis of this difference. The authors report the discovery of a previously unrecognized organelle gatekeeper function, mediated by UNC-16 (JIP3 in humans), that acts at the axon initial segment to restrict the flow of Golgi and endosomal organelles into the synaptic region of axons.
Genome Integrity and Transmission
Novel proteins required for meiotic silencing by unpaired DNA and siRNA generation in Neurospora crassa, pp. 91-100
T. M. Hammond, H. Xiao, E. C. Boone, L. M. Decker, S. A. Lee, T. D. Perdue, P. J. Pukkila, and P. K. Shiu
Identification of small RNAs associated with meiotic silencing by unpaired DNA, pp. 279-284
T. M. Hammond, W. G. Spollen, L. M. Decker, S. M. Blake, G. K. Springer, and P. K. Shiu
Genes unpaired during meiosis are silenced in Neurospora by
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Genetics Society of America