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Genetic patterns rise from huge yeast samples
Date:4/14/2010

it resided.

The scientists repeated this experiment with other chemicals that were toxic to most of the yeast, looking again and again for skewed genetic patterns of inheritance. Each time, they were able to locate gene regions pointing to specific traits, confirming that the method worked.

Viewing their success, Ehrenreich said, "It's really been a combination of having the technology to do this genotyping precisely and also being able to survey such a large number of individuals simultaneously."

From here, the team intends to use the information it has on gene regions and markers to fine tune the method and identify the specific genes associated with each trait, and to extend the method to many other yeast strains.

Detlef Weigel, director of the Max Planck Institute for Developmental Biology in Germany, already sees additional applications for the technique. "The new work by Dr. Kruglyak and colleagues beautifully showcases how new sequencing technologies are revolutionizing genetics," he said. "While the work was carried out with yeast, I am convinced that it can be easily extended to any other genetically tractable organism, including crop plants."


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Contact: Kitta MacPherson
kittamac@princeton.edu
609-258-5729
Princeton University
Source:Eurekalert  

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