Navigation Links
Genetic diagnosis can rule out a suspected Huntington's chorea patient

Huntington's disease is an autosomal-dominant inherited neurodegenerative disease with a distinct phenotype, but the pathogenesis is unclear. Although patients with a family history have more typical clinical symptoms, signs, and pathological changes, as well as an unambiguous clinical diagnosis, other diseases with dance-like movements, e.g., dentatorubral-pallidoluy-sian atrophy, spinocerebellar ataxia type 17, Huntington's disease-like-2, and neuroferritinopathy, are difficult to identify and distinguish from Huntington's disease. By mutation screening for CAG repeats in the Huntington's disease-associated candidate gene, IT15, using reverse transcription-polymerase chain reaction, T-A cloning, and sequencing, Dr. Mingxia Yu and coworkers from Zhongnan Hospital of Wuhan University in China provide a global analysis incorporating clinical symptoms, imaging examinations, and gene diagnosis, of Huntington's disease. Their findings, published in the Neural Regeneration Research (Vol. 9, No. 4, 2014), suggest that clinical diagnosis of Huntington's disease requires a combination of clinical symptoms, radiological changes, and genetic diagnosis.


Contact: Meng Zhao
Neural Regeneration Research

Page: 1

Related biology news :

1. Small variations in genetic code can team up to have a bi
2. Prostate cancer and blood lipids share genetic links
3. Octillions of microbes in the seas: Ocean microbes show incredible genetic diversity
4. Higher calcium intake may reduce body fat, mitigating genetic risk for diabetes
5. Genetic disorder causing strokes and vascular inflammation in children has been discovered
6. Tsetse fly genetic code sequenced
7. Genetic legacy of rare dwarf trees is widespread
8. Autism Genome Project delivers genetic discovery
9. Genetic code of the deadly tsetse fly unraveled
10. Genetics risk, prenatal smoking may predict behavioral problems
11. Genetic study tackles mystery of slow plant domestications
Post Your Comments:
Related Image:
Genetic diagnosis can rule out a suspected Huntington's chorea patient
(Date:10/29/2015)...  The J. Craig Venter Institute (JCVI) policy group ... Biosecurity: Lessons Learned and Options for the Future," which ... Services guidance for synthetic biology providers has worked since ... --> --> Synthetic biology promises great ... pose unique biosecurity threats. It now is easier than ...
(Date:10/29/2015)... NXTD ) ("NXT-ID" or ... the growing mobile commerce market and creator of ... leading marketplace to discover and buy innovative technology ... on StackSocial for this holiday season.   ... a biometric authentication company focused on the growing ...
(Date:10/27/2015)... Calif. , Oct. 27, 2015 Synaptics Inc. ... solutions, today announced that Google has adopted the Synaptics ... touch controller solutions to power its newest flagship smartphones, ... by Huawei. --> ... like Google to provide strategic collaboration in the joint ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... InSphero AG, ... 3D cell culture models, has promoted Melanie Aregger to serve as Chief Operating Officer. ... Aregger served on the management team and was promoted to Head of ...
(Date:11/24/2015)... , Nov. 24, 2015 /CNW Telbec/ - ProMetic Life ... announced today that Mr. Pierre Laurin , President and ... presentation at the upcoming Piper Jaffray 27 th Annual ... Hotel, on December 1-2, 2015. st , ... for one-on-one meetings throughout the day. The presentation will be ...
(Date:11/24/2015)... Va. , Nov. 24, 2015 ... focused on discovering drugs for metabolic disorders, announced ... to its Board of Directors (BOD). Mr. ... officer of Human Genome Sciences (HGS), and also ... Organization. Jim Powers , Chairman and ...
(Date:11/24/2015)... NEW YORK , November 24, 2015 ... in a European healthcare ... in which the companies will work closely together in identifying ... of unmet medical need. The collaboration is underpinned by a ... LSP fund. This is the first investment by Bristol-Myers Squibb ...
Breaking Biology Technology: