Navigation Links
Genetic and clinical factors best to predict late recurrence in estrogen receptor POS breast cancer
Date:5/2/2013

of adjuvant endocrine therapy beyond five years, we still see two-thirds of breast cancer deaths occurring after this time. Clearly, the identification of women that are at risk for these late types of recurrences is an important clinical research goal," said Dr Dubsky, who was not involved in the study.

"Sestak and colleagues provide highly relevant new data to meet this end: they have compared five different prognostic scores in order to predict outcome beyond the first five years of follow-up. Of note, none of these scores were primarily trained to specifically predict late recurrence. They show that a Clinical Treatment score (CTS) contained most of the prognostic information relevant to late distant metastases. Interestingly, only the Risk of Recurrence (ROR) score (PAM50) and the Breast Cancer Index (BCI) score provided additional information to the CTS. This data will need further validation before actually being incorporated into clinical decision-making concerning adjuvant endocrine therapy beyond five years."

These findings are similar to those proposed by the Austrian Breast and Colorectal Cancer Study Group recently, Dr Dubsky said. "The Endopredict Score was able to add additional prognostic information to clinical variables concerning distant metastases occurring later than five years after diagnosis. Future research should further address which are the biologic motifs behind late recurrences. Furthermore, molecular tools specifically designed to predict late metastasis should be developed."


'/>"/>

Contact: Vanessa Pavinato
media@esmo.org
European Society for Medical Oncology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study examines effects of genetic variants for infants with neonatal abstinence syndrome
2. Genetics Society of Americas GENETICS journal highlights for May 2013
3. Europe needs genetically engineered crops, scientists say
4. Epigenetic changes shed light on biological mechanism of autism
5. Genetic circuit allows both individual freedom, collective good
6. Genetics defines a distinct liver disease
7. BGI Health forms partnership with ACIBADEM hospital on genetic disease testing
8. Genetic discovery found to influence obesity in people of African ancestry
9. Ludwig presents advancements in immunotherapy and epigenetics at the American Association for Cancer Research Annual Meeting
10. Ludwig advancements in immunotherapy and epigenetics top scientific program at AACR
11. First genetic factor in prostate cancer prognosis identified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... 30, 2014  Aware, Inc. (NASDAQ: AWRE ... previously announced on June 26, 2014 that its Board ... $1.75 per share, or approximately $40 million in total.  ... 2014 and a payment date of July 24, 2014.  ... had set an ex-dividend date for this special cash ...
(Date:7/10/2014)... 2, 2014 NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company ... Gino Pereira was interviewed on July 1 st ... Tampa Florida . Mr. Pereira discusses the company,s next ... and how the Wocket™ aims to replace a traditional ... Cedric Harris tells Gino he has never heard ...
(Date:7/10/2014)... York , July 7, 2014 ... Transparency Market Research "Electronic Access Control Systems Market Global ... - 2019," the global Electronic Access Control systems market ... is expected to grow at a CAGR of 12.6% ... of USD 31,187.8 million in 2019. Browse ...
Breaking Biology News(10 mins):NASDAQ Sets Ex-Dividend Date for Aware, Inc.'s Special Cash Dividend of $1.75 Per Share 2Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 2Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 3Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 4Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 2Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 3Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 4Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research 5
... it, cuckoos do it cheating to score a ... even plants. But microscopically small, single-celled algae? Yes, they ... department of ecology and evolutionary biology have discovered., "There ... said William Driscoll, lead author of a research report ...
... changing climate are altering growing conditions in temperate rain ... affected, according to research conducted by the U.S. Forest ... in the January 2013 issue of Science Findings ... of forest plant responses to a warming climate. ...
... First trimester abortions are just as safe when performed by ... when conducted by physicians, according to a new six-year study ... the American Journal of Public Health in advance ... before the 40th anniversary of the Roe vs. Wade, the ...
Cached Biology News:They hunt, they kill, they cheat: Single-celled algae shed light on social lives of microbes 2They hunt, they kill, they cheat: Single-celled algae shed light on social lives of microbes 3They hunt, they kill, they cheat: Single-celled algae shed light on social lives of microbes 4Climate change's effects on temperate rain forests surprisingly complex 2Abortions are safe when performed by advanced practice nurses and physician assistants, study shows 2Abortions are safe when performed by advanced practice nurses and physician assistants, study shows 3
(Date:7/10/2014)... Ind. , July 10, 2014 /PRNewswire/ ... its use of capnography for respiratory monitoring ... group of healthcare leaders in embracing state-of-the-art ... how effectively patients are breathing and can ... occurs. By measuring the amount of carbon ...
(Date:7/10/2014)... THOUSAND OAKS, Calif., July 10, 2014   Ceres, ... biotechnology and seed company, announced today financial results for ... an update on its business. Ceres reported ... progress in product performance this growing season in Brazil, ... that affected the company,s sorghum evaluation areas for part ...
(Date:7/10/2014)... the basis of psychiatric disorders has been extremely challenging ... risk but are insufficient to cause disease. Now investigators ... Press journal Cell Stem Cell describe a ... risks interact with other risk factors or environmental exposures ... research pinpoints a genetic variant that may predispose individuals ...
(Date:7/10/2014)... the University of Illinois at Urbana-Champaign provides new ... of spin and heat at the nanoscale, and ... for data storage and information processing. , ... momentum. In a typical charge current, electrons, spin-angular-momentum ... explained David Cahill, a professor of materials science ...
Breaking Biology Technology:Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9New strategy could uncover genes at the root of psychiatric illnesses 2University of Illinois study advances limits for ultrafast nano-devices 2
... 11 Ceres, Inc. announced today,that it has begun ... Crops label. The highly anticipated launch marks the first ... materials,for biofuels and biopower. The company simultaneously launched a ... The company reported that the first ...
... Inc. (Nasdaq: PPHM ) today announced that Thomas A. ... on Wednesday. Dr. Waltz had been a director of Peregrine ... of his death, Dr. Waltz served on Peregrine,s Audit Committee, Compensation ... "The sudden loss of our business colleague and friend ...
... Dec. 11 Cornerstone Therapeutics Inc. (Nasdaq: ... on developing and commercializing prescription medications for respiratory ... of its integration activities following the closing of ... Cornerstone BioPharma Holdings, Inc. on October 31, 2008, ...
Cached Biology Technology:First Seed Sales of Dedicated Energy Crops Begin 2First Seed Sales of Dedicated Energy Crops Begin 3Peregrine Pharmaceuticals Mourns Loss of Chairman Thomas A. Waltz 2Cornerstone Therapeutics Provides Update on Integration Activities and Issues 2008 Revenue Guidance 2Cornerstone Therapeutics Provides Update on Integration Activities and Issues 2008 Revenue Guidance 3Cornerstone Therapeutics Provides Update on Integration Activities and Issues 2008 Revenue Guidance 4Cornerstone Therapeutics Provides Update on Integration Activities and Issues 2008 Revenue Guidance 5
quantitation of phosphatase activity, evaluation of hits and leads from HTS...
... ISO 9001:2000 Certified USDA Research Registered ... SOP's Training AALAS Certified Technicians ... Procedures GLP Documentation Upon Request Focus ... point for all your custom immunology service ...
Request Info...
Request Info...
Biology Products: