Navigation Links
Genetic ancestry: A new look at racial disparities in head and neck cancer
Date:9/26/2010

DETROIT Head and neck cancer outcomes associated with race may be more closely linked to social and behavioral factors than biological differences, especially for African Americans, according to a new Henry Ford Hospital study.

Researchers found that while those who self-reported to be African American are at greater risk for late stage cancer, there was no correlation between patients' genetic ancestry and cancer stage or survival.

In fact, the study shows only 5 percent of patients who self-reported to be African American had more than 95 percent West African ancestry.

"We believe this is the first piece of evidence using genetic race to take a closer look at outcomes with respect to stage early or late and survival in patients with head and neck cancer," says study lead author Maria J. Worsham, Ph.D., director of research in the Department of Otolaryngology at Henry Ford Hospital.

"We know that African Americans are disproportionately diagnosed with late-stage cancer and have worse outcomes than Caucasians. While there has been no real consensus on the causes for this difference, it is possible access to care, stage at diagnosis and insurance status may be factoring into the equation."

Study results will be presented Sept. 26 at the American Academy of OtolaryngologyHead & Neck Surgery Foundation Annual Meeting in Boston.

In 2009, there were an estimated 35,720 new cases of head and neck squamous cell carcinoma (HNSCC) and approximately 7,600 deaths. Smoking and alcohol use are the primary risk factors for this type of cancer.

African Americans are more likely to be diagnosed with late-stage HNSCC and have worse survival than Caucasians. It's unknown whether significant biological rather than socioeconomic differences account for some of the disparities in outcomes.

Since self-reported race doesn't always offer a complete picture of a person's biologic make-up, Dr. Worsham
'/>"/>

Contact: Krista Hopson
khopson1@hfhs.org
313-874-7207
Henry Ford Health System
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Rare genetic disorder gives clues to autism, epilepsy, mental retardation
2. Genetic Engineering & Biotechnology News reports on growing role of molecular diagnostics
3. Study finds genetic variant plays role in cleft lip
4. Genetic finding implicates innate immune system in major cause of blindness
5. American College of Medical Genetics receives $13.5M NIH contract
6. Clue to genetic cause of fatal birth defect
7. Can genetic information be controlled by light?
8. The American Society of Human Genetics hosts 58th Annual Meeting in Philadelphia
9. Modern genetics vs. ancient frog-killing fungus
10. Genetic based human diseases are an ancient evolutionary legacy
11. Genetic evidence for avian influenza movement from Asia to North America via wild birds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Genetic ancestry: A new look at racial disparities in head and neck cancer
(Date:9/18/2014)... acquire and creatively manipulate spoken language is unique to ... 6 million years of human evolution to make this ... candidate gene we now have," says Wolfgang Enard, Professor ... efforts to understand the molecular biological basis of language ... results of his latest study, undertaken in collaboration with ...
(Date:9/18/2014)... 18, 2014Many Americans across racial and ethnic groups ... impact on their day-to-day life, more so than ... and speech (57% of African-Americans, 49% of non-Hispanic ... When asked which disease or ailment is the ... first among African-Americans followed by AIDS/HIV. Hispanics ...
(Date:9/18/2014)... The global cycles of carbon and nitrogen comprise ... human and environmental systems have caused imbalances and ... greenhouse gases (GHGs). Increased GHGs result in climate ... terrestrial ecosystems, oceans and the atmosphere. Understanding these ... exciting branch of environmental science during the past ...
Breaking Biology News(10 mins):Language evolution: Quicker on the uptake 2Language evolution: Quicker on the uptake 3Americans rate losing eyesight as having greatest impact on their lives 2Americans rate losing eyesight as having greatest impact on their lives 3Greenhouse gas research enters a new era 2
... attacks in the United States in 2001 the threat ... perhaps from smallpox, plague or tularemia -- became very ... and rapidly contain an attack is still being developed. ... Center for Quantum Devices have demonstrated solar-blind avalanche photodiodes ...
... than men despite the popular notion that the opposite is ... pain have found that not only do women report more ... it in more bodily areas, more often and for longer ... be differences in how men and women think and feel ...
... $52.7 million research program that will help reveal the ... and point the way to designing new medicines. Under ... Structural Genomics Consortium (NESG) will conduct the five-year undertaking. ... history, will reinforce our dynamic position in the biomedical ...
Cached Biology News:Tiny avalanche photodiodes target bioterrorism agents 2Women feel more pain than men, research shows 2Women feel more pain than men, research shows 3Rutgers to lead $52.7 million protein research program 2Rutgers to lead $52.7 million protein research program 3Rutgers to lead $52.7 million protein research program 4
(Date:9/18/2014)... 2014 Research and Markets ... N-acetylcysteine Industry Report 2014" report to their ... Report 2014 is a professional and in-depth study ... industry. The report provides a basic ... and industry chain structure. The N-acetylcysteine market analysis ...
(Date:9/18/2014)... Research and Markets has announced the addition ... In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to ... The global companion diagnostics market is expected to grow ... Factors such as rising need for personalized medicine in ... pharmaceutical industry, support from regulatory authorities, and emerging technologies ...
(Date:9/18/2014)... LOUIS , Sept. 18, 2014  U.S. biotech ... by signing an exclusive license for technology developed by ... control gene expression in plants, including for applications in ... The technology was developed under the ... officer at Kultevat and former president of the Danforth ...
(Date:9/18/2014)... , Sept. 18, 2014  Neogen Corporation (Nasdaq: ... entered into a strategic agreement with Merck Animal Health ... The Igenity Dairy Heifer Program consists ... information on the genetic potential of replacement dairy heifers. ... calf is born, and is an excellent tool in ...
Breaking Biology Technology:Global N-acetylcysteine Industry Report 2014 2Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 2Global Companion Diagnostics (Polymerase Chain Reaction, In-situ hybridization, Immunohistochemistry) Market - Trends & Forecasts to 2019 3Kultevat obtains license of gene switch technology 2Merck Animal Health to market Neogen's dairy genomic program 2
... Companies in Plant Biotechnology Industry, WILMINGTON, Del., Oct. ... one of the best employers in the biotechnology and,pharmaceutical ... This is the first DuPont appearance on the ... it ahead of other companies in the,plant biotechnology industry. ...
... 18 NPS,Pharmaceuticals, Inc. (Nasdaq: NPSP ) announced ... offer for any and all of its outstanding,3.0% Convertible ... New,York City time, on October 17, 2007. As ... million principal,amount of the notes, representing approximately 99.7% of ...
... -- Company Completes Enrollment in First Cohort --, ... Nventa,Biopharmaceuticals Corporation (TSX:NVN) today announced that the Company,has ... Phase 1 clinical trial,to assess the safety and ... neoplasia (CIN). The trial is expected to ...
Cached Biology Technology:DuPont Named Among Top Biotechnology Employers by Science Magazine 2NPS Pharmaceuticals Announces Results of Tender Offer 2NPS Pharmaceuticals Announces Results of Tender Offer 3Nventa updates progress of cervical dysplasia trial with new HspE7 2Nventa updates progress of cervical dysplasia trial with new HspE7 3Nventa updates progress of cervical dysplasia trial with new HspE7 4Nventa updates progress of cervical dysplasia trial with new HspE7 5
Mycoplasma and virus tested...
... MagicMark XP Western Protein Standards are ... protein molecular weight estimation directly on ... an IgG binding site, allowing direct ... used to detect your target protein ...
... Clone/PAD: 3F10B10. Immunogen: Synthetic ... region of JAB1 (Jun activation ... Specificity: Specific for the JAB1 ... controls: 293T Jurkat cell lysates). ...
...
Biology Products: