Navigation Links
Genetic adaptations key to microbe's survival in challenging environment

The genome of a marine bacterium living 2,500 meters below the ocean's surface is providing clues to how life adapts in extreme thermal and chemical gradients, according to an article published Feb. 6 in the journal PLoS Genetics, an open-access publication published by the Public Library of Science.

The research focused on the bacterium Nautilia profundicola, a microbe that survives near deep-sea hydrothermal vents. Microorganisms that thrive at these geysers on the sea floor must adapt to fluctuations in temperature and oxygen levels, ranging from the hot, sulfide- and heavy metal-laden plume at the vents' outlets to cold seawater in the surrounding region.

The study combined genome analysis with physiological and ecological observations to investigate the importance of one gene in N. profundicola. That gene, called rgy, allows the bacterium to manufacture a protein called reverse gyrase when it encounters extremely hot fluids from the Earth's interior.

Previous studies found the gene only in microorganisms growing in temperatures greater than 80C, but N. profundicola thrives best at much lower temperatures.

"The gene's presence in N. profundicola suggests that it might play a role in the bacterium's ability to survive rapid and frequent temperature fluctuations in its environment," said Assistant Professor of Marine Biosciences Barbara Campbell, the study's lead scientist.

Additional University of Delaware contributors were Professor of Marine Biosciences Stephen Craig Cary, Assistant Professor of Marine Biosciences Thomas Hanson, and Julie Smith, marine biosciences doctoral student. Also collaborating on the project were researchers from the Davis and Riverside campuses of the University of California; the University of Louisville; the University of Waikato in Hamilton, New Zealand; and the J. Craig Venter Institute in Rockville, Md.

The researchers also uncovered further adaptations to the vent environment, including genes necessary for growth and sensing environmental conditions, and a new route for nitrate assimilation related to how other bacteria use ammonia as an energy source. Photosynthesis cannot occur in the hydrothermal vents' dark environment, where hot, toxic fluids oozing from below the seafloor combine with cold seawater at very high pressures.

These results help to explain how microbes survive near the vents, where conditions are thought to resemble those found on early Earth. Nautilia profundicola contains all the genes necessary for life in conditions widely believed to mimic those in our planet's early biosphere and could aid in understanding of how life evolved.

"It will be an important model system," Campbell said, "for understanding early microbial life on Earth."


Contact: Elizabeth Boyle
University of Delaware

Related biology news :

1. CSHL scientists discover how companion cells to sperm protect them from genetic damage
2. Genetic study shows direct link between vitamin D and MS susceptibility gene
3. Effectiveness of progesterone in reducing preterm births may be altered by genetic predisposition
4. CSHL scientists clarify editing error underlying genetic neurodegenerative disease
5. Researchers identify 4 genetic hotspots associated with psoriasis
6. Scientists uncover new genetic variations linked to psoriasis
7. Consumers desire more genetic testing, but not designer babies
8. Far-reaching genetics topics to be addressed: 2009 Annual Clinical Genetics Meeting, March 25-29
9. Scientists unlock possible aging secret in genetically altered fruit fly
10. Researchers genetically link Lou Gehrigs disease in humans to dog disease
11. Genetic testing not cost-effective in guiding initial dosing of common blood thinner
Post Your Comments:
Related Image:
Genetic adaptations key to microbe's survival in challenging environment
(Date:5/3/2016)... , May 3, 2016  Neurotechnology, a provider ... MegaMatcher Automated Biometric Identification System (ABIS) , ... multi-biometric projects. MegaMatcher ABIS can process multiple complex ... any combination of fingerprint, face or iris biometrics. ... SDK and MegaMatcher Accelerator , which ...
(Date:4/26/2016)... DUBLIN , April 27, 2016 ... of the  "Global Multi-modal Biometrics Market 2016-2020"  report ... ) , The analysts forecast ... a CAGR of 15.49% during the period 2016-2020.  ... a number of sectors such as the healthcare, ...
(Date:4/14/2016)... TEL AVIV, Israel , April 14, 2016 /PRNewswire/ ... in Behavioral Authentication and Malware Detection, today announced the ... has already assumed the new role. Goldwerger,s ... for BioCatch, on the heels of the deployment of ... In addition, BioCatch,s behavioral biometric technology, which discerns unique ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... Parallel ... clinical trials, announced today the Clinical Reach Virtual Patient Encounter CONSULT module ... circle with the physician and clinical trial team. , Using the CONSULT module, patients ...
(Date:6/27/2016)...   Ginkgo Bioworks , a leading organism ... today awarded as one of the World Economic ... most innovative companies. Ginkgo Bioworks is engineering biology ... world in the nutrition, health and consumer goods ... customers including Fortune 500 companies to design microbes ...
(Date:6/24/2016)... Raleigh, NC (PRWEB) , ... June 24, 2016 , ... ... find the most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings ... here to read it now. , Diagnostic biomarkers are signposts in the blood, ...
(Date:6/23/2016)... TORONTO , June 23, 2016 /PRNewswire/ - ... Ontario biotechnology company, Propellon ... the development and commercialization of a portfolio of ... cancers. Epigenetic targets such as WDR5 represent an ... contribute significantly in precision medicine for cancer patients. ...
Breaking Biology Technology: