Navigation Links
Genetic Engineering & Biotechnology News reports on growing use of cell-based assays
Date:4/16/2008

New Rochelle, NY, April 16, 2008Biotech and pharma companies are increasingly relying on cell-based assays in early drug discovery work, reports Genetic Engineering & Biotechnology News (GEN). The technique can provide a quick and lower cost means of testing drug candidates for toxic effects, according to an article in the April 15 issue of GEN (http://www.genengnews.com/articles/chitem.aspx?aid=2437).

Better screening technologies, noninvasive monitoring, and more automation are driving the trend toward adoption of this technology, notes John Sterling, Editor-in-Chief of GEN. Some estimates project that the market for cell-based assays will more than double over the next six or seven years to over $230 million. This is definitely a methodology that should draw the interest of new drug developers.

More than 50% of currently marketed drugs target GPCRs, which impact a wide range of cellular processes. Multispan is looking to exploit this area and is collaborating with Promega and Molecular Devices to develop an array of applications for its GPCR cell-based assays.

Another field of much R&D interest involves protein-protein interactions. DiscoveRx created a new family of cell-based assays for the detection of protein-protein interactions using an enzyme fragment complementation assay. This system uses an enzyme acceptor, an inactive alpha-galactosidase enzyme that binds to its enzyme donor forming an active enzyme that will hydrolyze a substrate and provide a signal.


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert

Page: 1

Related biology news :

1. Does the desire to consume alcohol and tobacco come from our genetic makeup?
2. Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
3. Many parents at-risk for cancer disclose genetic test results to children
4. Genetics determine optimal drug dose of common anticoagulant
5. Claims of sex-related differences in genetic association studies often not properly validated
6. American College of Medical Genetics responds to new FDA labeling decision for warfarin
7. UNC study questions FDA genetic-screening guidelines for cancer drug
8. Genome study shines light on genetic link to height
9. Selexis Announces Advanced Approach to Maximize Power of Genetic Elements for Rapid Development of High Performance Cell Lines
10. Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring
11. Rutgers Genetics receives $7.8 million for autism research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... , Dec. 10, 2014  That blood pressure plays ... a while. Hypertension – the medical term for high blood ... early 1800s, and the inflatable cuff that,s used in measuring ... however, mean there,s nothing new about hypertension, its triggers and ... beliefs about the condition and the best ways to treat ...
(Date:12/10/2014)... N.C. , Dec. 9, 2014  Valencell, a ... it is seeing a staggering demand from its licensees ... the Company revealed, is not solely coming from fitness ... as well. "A wearable is only as ... result, accuracy is the ultimate driver in long-term mass ...
(Date:12/10/2014)... Dec. 08, 2014 Research and Markets ... of the "Biometrics Market in Japan 2014-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 The integration ... as rural banking and upgradation of the driver,s ... in the market. Besides the aforementioned projects, biometrics ...
Breaking Biology News(10 mins):Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4Wearable Technology Products Demand Highly Accurate Biometric Technology 2Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2
... investigating how quickly the Deepwater Horizon oil carried into Gulf ... natural microbial communities, and whether native oil-eating bacteria that wash ... What oceanography professors Markus Huettel and Joel E. Kostka ... oil in the beaches will be gone. Their findings may ...
... to all that ails people managing their multiple sclerosis is depression ... as 50 percent. Yet despite its prevalence, the ... how severe one,s MS is, and it can occur at any ... psychological reaction that comes from dealing with the burden of a ...
... article in the current issue of Global Change Biology ... Jatropha curcas L. , for present and future climates. ... Jatropha , with biogeographic modeling and ecological principles. This ... and map worldwide productivity for present and future climates. ...
Cached Biology News:How fast can microbes break down oil washed onto Gulf beaches? 2How fast can microbes break down oil washed onto Gulf beaches? 3Brain atrophy responsible for depression in people battling multiple sclerosis 2
(Date:12/24/2014)... December 23, 2014 Earlier this year ... L. Sherley, director of the Adult Stem Cell Technology ... often overlooked and under appreciated unique property of adult ... Distributed Stem Cells: Misunderstood in the Past, Important for ... congress participants. He gave the address at the ...
(Date:12/24/2014)... Dallas, Texas (PRWEB) December 23, 2014 ... on methyl mercaptan such as its definition, ... also presents product specification, manufacturing process, and ... regions, technology and applications. The analysis also ... survey, marketing channels, industry development trend and ...
(Date:12/24/2014)... BEIJING , Dec. 23, 2014 ... or the "Company"), a leading fully integrated plasma-based ... today announced that its majority-owned subsidiary, Shandong Taibang ... Practices ("GMP") certification from the China Food and ... factor production facility. As previously disclosed in the ...
(Date:12/24/2014)...  Rock Creek Pharmaceuticals, Inc., (NASDAQ: RCPI ... Trial Application (CTA) with the United Kingdom,s ... regulatory approval to initiate clinical trials for the continued ... Contingent on the Company receiving CTA regulatory approval, the ... assess the safety, tolerability and dose escalation of Anatabine ...
Breaking Biology Technology:Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3
... 27, 2011  Candelis announced today that it has reached ... ) whereby Candelis, ASTRA cloud-hosted suite of services will ... images and studies to patients, Microsoft HealthVault accounts upon ... personal health application platform that lets consumers gather, store ...
... Immunicum, which is developing cancer vaccines, has received approval ... clinical trial. The study will be conducted on kidney cancer ... time, the company secures substantial financing to complete the clinical ... to test the vaccine on humans for the first time. ...
... the breeze doesn,t always blow and therein lie perhaps the ... a grand scale. If only there were an efficient, ... quantities of excess power generated on windy or sunny days ... let,s imagine the battery is cheap to build, too. ...
Cached Biology Technology:Candelis and Microsoft Team Up to Empower Patients 2Candelis and Microsoft Team Up to Empower Patients 3A New Type of Dendritic Cell-Based Cancer Vaccine has Received Approval for Clinical Tests and at the Same Time Secures Substantial Financing 2Nanoparticle electrode for batteries could make grid-scale power storage feasible 2Nanoparticle electrode for batteries could make grid-scale power storage feasible 3Nanoparticle electrode for batteries could make grid-scale power storage feasible 4
... CLS number is a ... to easily match Cornings ... no availability yet, please ... Sigma-Aldrich number (Z71,381-3) or ...
... This CLS number is ... to easily match Cornings product ... yet, please order under the ... contact customer service for assistance. ...
... Anti-YAP Polyclonal Antibody ... purified rabbit polyclonal antibody. Detects 70 ... in Western blotting and immunohistochemistry. ... proliferation Storage: ...
... Stain for Mass Spectrometry Applications ,In ... (MS) has emerged as a powerful protein ... 2-D gels is now an important intermediate ... leads ultimately to identification of specific proteins ...
Biology Products: