Navigation Links
Genes under control
Date:3/30/2010

In order for a gene to create a protein, the gene's DNA must first be converted into what's known as messenger RNA. These RNA molecules are the instruction manuals that show the ribosomes the cell's protein factories how to build a protein. A few years ago, scientists studying bacterial cells discovered sections in certain messenger RNAs that metabolic products (metabolites) can bind to. In doing so, they induce the RNA molecule to change its spatial structure and make it possible to switch protein production on or off. For the bacteria, these sections the riboswitches provide a fast and efficient way of controlling protein synthesis. Unsurprisingly, it had previously been impossible to demonstrate the presence of such riboswitches in the chloroplasts of plant cells.

Max Planck scientists based in Golm near Potsdam were recently the first to modify and insert riboswitches into the genetic material of the chloroplast in order to control the formation of certain chloroplast proteins. The scientists smuggled a gene into the chloroplast DNA and equipped it with a riboswitch. Theophylline, a substance found in the tea plant, was used as the "switch": it has the capacity to bind to the riboswitch on the messenger RNA, thereby enabling the chloroplast ribosomes to read the RNA. "When we spray the tobacco plants with theophylline, we find that the chloroplasts form the corresponding protein. In the absence of theophylline, no protein is produced. So the theophylline riboswitch allows us to switch a gene on or off at will and see what effects result," explains Ralph Bock from the Max Planck Institute of Molecular Plant Physiology. This had previously been a difficult thing to achieve, given that the chloroplast genome contains numerous genes which are essential for survival. Switching one of these genes off permanently would result in the death of the cell, rendering it useless for further investigation.

However, studying the way chloroplasts work
'/>"/>

Contact: Ralph Bock
rbock@mpimp-golm.mpg.de
49-331-567-8700
Max-Planck-Gesellschaft
Source:Eurekalert

Page: 1 2

Related biology news :

1. Autism susceptibility genes identified
2. Searching for genes behind a trait
3. Genome mapping technique speeds process of finding specific genes
4. Genes may exert opposite effects in diabetes and inflammatory bowel disease
5. Study finds genes that keep watch on blood clotting time
6. A fingerprint for genes
7. New research shows genes of pregnant women and their fetuses can increase the risk of preterm labor
8. TGen becomes center of excellence for Horizon Discoverys GENESIS and X-MAN technology
9. Ability to navigate may be linked to genes, researcher says
10. Are new genes always better?
11. Genes found linked to breast cancer drug resistance could guide future treatment choices
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... -- Newest Market IPO,s and exchange ... significant investor attention with news concerning shareholder updates and new ... NXT-ID, Inc. (NASDAQ: NXTD ), Alibaba Group Holding ... MBLY ), GoPro, Inc. (NASDAQ: GPRO ) ... (NASDAQ: NXTD ) recently completed an essential round ...
(Date:9/22/2014)... ATLANTA September 23, 2014 A new American ... Supplemental Nutrition Assistance Program (SNAP), previously known as ... scores compared with income eligible non-participants. The authors ... programs aimed at enhancing the dietary quality of ... assist low-income individuals and households with the resources ...
(Date:9/22/2014)... genetic sequencing technologies continue to evolve rapidly, becoming part ... establish appropriate policies and regulatory frameworks to address potential ... policy issue of the Journal of Law, Medicine ... experts with the Center for Medical Ethics and Health ... the tools to jumpstart this process. , Experts ...
Breaking Biology News(10 mins):Latest Blockbuster IPOs and Up Listings for Global Tech Stocks Attracting Major Attention as Traders Focus on Key Economic Data Due this Week 2Latest Blockbuster IPOs and Up Listings for Global Tech Stocks Attracting Major Attention as Traders Focus on Key Economic Data Due this Week 3Latest Blockbuster IPOs and Up Listings for Global Tech Stocks Attracting Major Attention as Traders Focus on Key Economic Data Due this Week 4Latest Blockbuster IPOs and Up Listings for Global Tech Stocks Attracting Major Attention as Traders Focus on Key Economic Data Due this Week 5Latest Blockbuster IPOs and Up Listings for Global Tech Stocks Attracting Major Attention as Traders Focus on Key Economic Data Due this Week 6Latest Blockbuster IPOs and Up Listings for Global Tech Stocks Attracting Major Attention as Traders Focus on Key Economic Data Due this Week 7Federal food program puts food on the table, but dietary quality could be improved 2Experts provide much-needed policy analysis for clinical integration of next generation sequencing 2Experts provide much-needed policy analysis for clinical integration of next generation sequencing 3
... The MRSA 'superbug' evades many of the measures introduced ... organism found almost everywhere in hospital wards, according to ... Scientists from the University of Bath have shown that ... called Acanthamoeba polyphaga, which is ubiquitous in the environment ...
... cancers actually share something in common ?a molecular "signature" made ... that target key cancer genes and promote malignant growth. ... emerging class of gene regulators and may also pave the ... The study appears online in the Proceedings of the National ...
... discovered that some type of protective system goes into ... is deficient. This discovery indicates a hidden safety net ... the immune system such as AIDS. The Mayo Clinic-led ... and is reported in the early online edition of ...
Cached Biology News:MRSA use amoeba to spread, new research shows 2Common molecular 'signature' identified in solid tumors 2Common molecular 'signature' identified in solid tumors 3Infant transplant patients resist infections that kill adult AIDS patients 2Infant transplant patients resist infections that kill adult AIDS patients 3
(Date:9/23/2014)... The Minnesota High Tech Association ... cellular modems , platforms and application-specific remote monitoring ... for the 2014 Tekne Awards. The awards ... Convention Center on Thursday, November 13th. The Tekne ... shown superior technology innovation and leadership. , ...
(Date:9/22/2014)... and SANTA CLARA, Calif. ... (NASDAQ: WBMD ), the leading source of ... WebMD/Medscape survey that provide novel insights regarding ... aiding diagnosis and care.  Dr. Eric Topol , ... digital medicine, who serves as both Editor-in-Chief of Medscape ...
(Date:9/22/2014)... in a mouse model of pancreatic cancer identified distinct ... including significant differences from the primary tumor that may ... their study reported in the Sept. 25 issue of ... Hospital (MGH) Cancer Center identified several different classes of ... to be targets for improved treatment of the deadly ...
(Date:9/22/2014)... D.C. (PRWEB) September 22, 2014 ... Georgetown President John DeGioia on Friday renewed their ... for an additional five years to expand the ... biosecurity, nonproliferation and global climate, energy and environmental ... of an MOU originally signed in December 2009 ...
Breaking Biology Technology:NimbeLink Named Finalist for 15th Annual Tekne Awards 2NimbeLink Named Finalist for 15th Annual Tekne Awards 3WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 2WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 3WebMD/Medscape Digital Technology Survey Reveals Unique Insights Into How Patients and Physicians Perceive the Role, Potential and Risks Associated with Digital Health Technologies 4Massachusetts General study reveals gene expression patterns in pancreatic CTCs 2Massachusetts General study reveals gene expression patterns in pancreatic CTCs 3Lawrence Livermore Renews Pact with Georgetown University to Expand Research and Education in Science and Policy 2
... Mass., March 19 MacroChem,Corporation (OTC Bulletin Board: ... to the position of Chief Financial Officer, effective,immediately. ... and Vice,President, Corporate Development since joining the Company ... CFO of Bioenvision, Inc. prior to its,successful merger ...
... Years In 2008 And, Beyond, According To The Latest Research Released By ... ... the economy slides into,recession, IBISWorld today announced its list of industries with ... of the top 10 industries which IBISWorld predicts to do,well in 2008 ...
... of Standards and Technology (NIST) have set the stage ... today built from semiconductor compounds and future generations of ... upcoming paper in the Journal of the American Chemical ... of organic molecules can be assembled on the same ...
Cached Biology Technology:MacroChem Appoints David P. Luci as New CFO 2MacroChem Appoints David P. Luci as New CFO 3The Recession List - Top 10 Industries to Fly and Flop in 2008 2The Recession List - Top 10 Industries to Fly and Flop in 2008 3The Recession List - Top 10 Industries to Fly and Flop in 2008 4The Recession List - Top 10 Industries to Fly and Flop in 2008 5The Recession List - Top 10 Industries to Fly and Flop in 2008 6NIST team proves bridge from conventional to molecular electronics possible 2
...
... Scalable SNPstream System Delivers 4,600 to Over ... SNPstream Genotyping System is capable of performing ... day. Part of the GenomeLab family of ... process up to 48 SNPs in each ...
... off-white solid. A nucleoside antibiotic that ... formation of N-glycosidic protein-carbohydrate linkages. Active ... bacteria, yeasts, fungi, and viruses. Inhibits ... on human T-lymphoblastoid cells. Also inhibits ...
... 220 V, is used for agitation and mixing ... staining and destaining of gels and blots, and ... (8-40 rpm) and can handle a maximum load ... two 29 x 21 cm platforms covered with ...
Biology Products: