Navigation Links
Genes may thwart seniors' exercise gains
Date:3/14/2014

Bethesda, Md. (March 14, 2014)Keeping strong and physically fit is crucial to maintaining independence among the elderly. Exercise has repeatedly been shown to reduce or slow age-related declines in physical function and is a widely recommended for seniors, but the way that older people respond to exercise varies widely. A new study by Thomas W. Buford et al. examines the ACE I/D gene and whether its variationsthe ID, DD, and II genotypesimpact some seniors' ability to fully reap the benefits of exercise.

Researchers followed 424 sedentary, mobility-limited seniors aged 70-89 for a year. Participants were randomly placed in a group that focused on either health education or physical activity. The health education group received ongoing presentations on eating right, how to properly use medication, and other information on maintaining a healthy lifestyle, but did not perform exercise as part of the study. Seniors in the physical activity group were taught a variety of strength (e.g., squats and leg raises) and balance exercises and a walking program that they were encouraged to perform both in a group setting and at home.

The researchers measured changes in walking speed and participants' ability to perform other tasks such as getting up from a chair. They found that the physical activity intervention led to greater improvements walking speed among ID and DD genotype carriers (29.9% and 13.7% respectively). However, among II genotype carriers, health education alone led to more improvements in walking speed than physical activity intervention (20% vs. 18.5%). II carriers in the physical activity group also experienced smaller gains in lower body performance than those in the health education group.

These findings suggest that the ACE I/D genotype may be a significant factor in how well seniors respond to exercise. This insight could be used to develop more effective, individualized, and senior-friendly exercise recommendations for improving physical function and preventing in disability. The full study "Genetic influence on exercise-induced changes in physical function among mobility-limited older adults" is published in Physiological Genomics: http://ow.ly/uAGUA.


'/>"/>

Contact: Stacy Brooks
sbrooks@the-aps.org
301-634-7209
American Physiological Society
Source:Eurekalert

Related biology news :

1. An equation to describe the competition between genes
2. Turings theory of morphogenesis validated 60 years after his death
3. Fossilized human feces from 14th century contain antibiotic resistance genes
4. Sequencing hundreds of nuclear genes in the sunflower family now possible
5. How do polar bears stay warm? Research finds an answer in their genes
6. Wasps use ancient aggression genes to create social groups
7. Clues to cancer pathogenesis found in cell-conditioned media
8. GW researcher finds connection in pathogenesis of neurological diseases, HIV
9. A digital test for toxic genes
10. Elsevier announces the launch of open access journal: Pathogenesis
11. Permanent changes in brain genes may not be so permanent after all
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
(Date:4/6/2017)... 2017 Forecasts by Product Type ... by End-Use (Transportation & Logistics, Government & Public Sector, ... Fossil Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation ... Are you looking for a definitive report on the ... ...
(Date:4/5/2017)... , April 5, 2017 Today HYPR ... that the server component of the HYPR platform is ... providing the end-to-end security architecture that empowers biometric authentication ... HYPR has already secured over 15 million users across ... manufacturers of connected home product suites and physical access ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... Linda, Ca (PRWEB) , ... April 20, 2017 ... ... University Virtual Event , this new webinar will explore challenging patient cases when ... admitted to the hospital, there may be a need for bridging parental anticoagulation ...
(Date:4/20/2017)...  Eli Lilly and Company (NYSE: LLY ... the prevention of migraine at the American Academy of ... 22-28, 2017, in Boston . ... including safety and patient outcomes data for galcanezumab in ... in monthly migraine headache days among patients with episodic ...
(Date:4/20/2017)... ... April 20, 2017 , ... ... scientific and clinical research community’s growing body of knowledge during its Eighth ... Gracie Theatre and the adjacent Darling Atrium. During the event, undergraduates, graduate students, ...
(Date:4/20/2017)... LAVAL, QC , April 20, 2017 /PRNewswire/ - Prometic Life ... today presented new results at the International Liver Congress ("ILC") ... Liver ("EASL") in Amsterdam on the ... in a mouse model of obesity and metabolic syndrome. ... According to Dr. Lyne Gagnon, ...
Breaking Biology Technology: