Navigation Links
Genes determine whether sugar pills work
Date:12/3/2008

It is a well-known fact in drug trials that individuals can respond just as well to placebos, sugar pills, as to the active drug. On the other hand, it is difficult to explain why only certain people get better from placebos. A team of researchers from Uppsala University and Gothenburg University have now found gene variants that can impact the placebo effect and a mechanism in the brain that characterizes those who respond to placebos.

The study, published in Journal of Neuroscience, examined 108 individuals suffering from social phobia using a brain camera (PET, positron emission tomography). The individuals were participating in a treatment study looking into how anxiety-moderating drugs affect brain activity. Just under one fourth of the subjects were given a placebo instead of a drug. This was a double-blind study, meaning that neither the subjects nor the research team know who was taking the drug or the sugar pill.

Before and after an eight-week period of treatment, the participants were asked to give a stressful oral presentation while their brain activity was monitored. When all the metering was finished and the study was decoded, it turned out that 40 percent of the placebo group had received the same degree of anxiety relief from the sugar pill as other groups got from a drug.

Those who responded well to the placebo had a significant reduction in activity in the amygdala in the temporal lobe, while this reduction was not found in the others. In previous research the amygdala has stood out as a key structure for emotional reactions. Both serotonin-active drugs (SSRI preparations) and cognitive behavioral therapy moderate activity in this area.

"Thus, successful placebo treatment works through the same mechanism in the brain," says Tomas Furmark at the Uppsala University Department of Psychology, who directed the study.

The study also analyzed two genes that influence the reabsorption and synth
'/>"/>

Contact: Tomas Furmark
tomas.furmark@psyk.uu.se
46-073-683-3487
Uppsala University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Einstein researchers develop technique to count messages made by single genes
2. Bipolar disorder genes, pathways identified by Indiana University neuroscientists
3. From genes to farmers fields
4. Researchers at IRB Barcelona produce more data on key genes in diabetes
5. Human genes sing different tunes in different tissues
6. NJIT professor finds engineering technique to identify disease-causing genes
7. Mapping a clan of mobile selfish genes
8. Genes that control cell death fingered in age-related hearing loss
9. Researchers continue to find genes for type 1 diabetes
10. Brainy genes, not brawn, key to success on mussel beach
11. New tool probes function of rice genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... , April 20, 2015 Huntington Memorial Hospital ... to implant a new miniaturized, wireless monitoring sensor to ... the first and only FDA-approved heart failure monitoring device ... when used by physicians to manage heart failure. ... is implanted in the pulmonary artery (PA) during a ...
(Date:4/14/2015)... YORK , April 14, 2015  HYPR ... IDentity Online (FIDO ® ) Alliance tm , ... specifications. FIDO members commit to share technology and ... methods that are interoperable, more secure and private, ... enable biometric identity verification that protects sensitive user ...
(Date:4/13/2015)... a leading cloud-based consumer engagement platform that provides trusted ... communities around health and wellness, announced today the launching ... The ... vehicle to receive validated health information from consumers. ... will allow higi,s trusted partners, on a user opt-in ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3
... In a new paper released today in Nature , ... Cech and Leslie Leinwand, detailed a new target for anti-cancer ... DNA. Researchers in the two scientists, laboratories collaborated ... by a drug docked onto the chromosome end at this ...
... The promise of stem cells seems limitless. If they can ... restoring ravaged immune systems, these malleable cells would revolutionize medical ... as scientists seek to better understand the role of these ... Friday, September 14, the Ruth L. and David S. ...
... 21, 2012) - It,s called mile-a-minute weed or "forest ... species that spreads quickly, covering crops, smothering trees and ... State University are spearheading a four-year research project that ... to be vulnerable to rapid environmental change, such as ...
Cached Biology News:CU-Boulder researchers uncover new target for cancer research 2Einstein hosts its first stem cell institute symposium 2Einstein hosts its first stem cell institute symposium 3'Forest killer' plant study explores rapid environmental change factors 2'Forest killer' plant study explores rapid environmental change factors 3
(Date:5/27/2015)... (PRWEB) May 27, 2015 The ... directing, via its wholly owned subsidiary, Anelixis Therapeutics ... treatment for ALS that targets the innate immune system. ... Therapy Development Institute received from the 2014 social media ... entire sum of $4 million raised directly by the ...
(Date:5/27/2015)... THOUSAND OAKS, Calif. , May 27, 2015 /PRNewswire/ ... company, has been awarded a U.S. patent for a ... gene in areas such as research, product development and ... useful in regulating key biosynthetic processes that are the ... to offer other seed companies a commercial license to ...
(Date:5/26/2015)... OTTAWA, Canada, and BELLINGHAM, Washington, USA (PRWEB) May 26, ... has signed a formal partnership with the ... Ottawa Centre for Extreme and Quantum Photonics. The center ... in the field of photonics, and will be only ... Arthurs, CEO of SPIE, the international society for ...
(Date:5/26/2015)... HILDEN, Germany , May 26, ... QGEN ; Frankfurt Prime Standard: QIA) today ... Insight ® (QCI™) bioinformatics content and software ... report on genomic variants identified in next-generation sequencing ... bioinformatics platform are in oncology, for somatic and ...
Breaking Biology Technology:Ice Bucket Challenge Advances Antibody Toward Clinical Trial for ALS 2Ice Bucket Challenge Advances Antibody Toward Clinical Trial for ALS 3Ceres Awarded Patent for Innovation in Soybean 2Ceres Awarded Patent for Innovation in Soybean 3Third Max Planck Centre in North America Inaugurated at University of Ottawa 2Third Max Planck Centre in North America Inaugurated at University of Ottawa 3QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 2QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 3QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 4QIAGEN Launches Clinical Bioinformatics Platform for Next-Generation Sequencing 5
... Researchers ... analysis have found that a combination of phenol based , ... array data than either method alone ... of RiboPure RNA Isolation Kits are the first kits that combine , ...
... Dicer and Escherichia coli ... vitro to cleave long dsRNA, producing siRNA cocktails that are , ... endoribonuclease that contains RNase ... enzyme responsible for cleavage of long dsRNAs to siRNA in the , ...
... Mike W. Byrom, Angie M. Cheng and Lance P. Ford* , Ambion, Inc. ... Austin, TX 78744-1832 , *Corresponding ... Abstract Small interfering RNA (siRNA) is an extremely , ... systems, including mammalian cells. Gene specific siRNAs have , ...
Cached Biology Technology:Improve RNA Isolation for Array Analysis and More 2Improve RNA Isolation for Array Analysis and More 3Improve RNA Isolation for Array Analysis and More 4Improve RNA Isolation for Array Analysis and More 5Improve RNA Isolation for Array Analysis and More 6Dicer vs. RNase III for Preparation of siRNA Cocktails 2Dicer vs. RNase III for Preparation of siRNA Cocktails 3Inducing RNAi with siRNA Cocktails Generated by RNase III 2Inducing RNAi with siRNA Cocktails Generated by RNase III 3Inducing RNAi with siRNA Cocktails Generated by RNase III 4Inducing RNAi with siRNA Cocktails Generated by RNase III 5Inducing RNAi with siRNA Cocktails Generated by RNase III 6Inducing RNAi with siRNA Cocktails Generated by RNase III 7Inducing RNAi with siRNA Cocktails Generated by RNase III 8Inducing RNAi with siRNA Cocktails Generated by RNase III 9
GOAT ANTI SLI...
Protein Phosphorylation...
ANTI L-DOPA...
... Automatic High Sensitivity Laboratory Osmometer for both 0.2 and 2.0 mL samples for ... and record keeping. Bar code reading capability with optional scanner. RS-232 port. ... ... ...
Biology Products: