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Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring

e agreements.

The principal investigators and approximate total funding levels are:

Genotyping Facilities

Stacey Gabriel, Ph.D., Broad Institute of MIT and Harvard, Cambridge, Mass.
A Center for GEI Association Studies
$3.8 million

David Valle, M.D., Center for Inherited Disease Research, Johns Hopkins University, Baltimore, Johns Hopkins University/Center for Inherited Disease Research
Genotyping for Genome-wide Association Studies
$3.5 million

Coordinating Center

Bruce Weir, Ph.D., University of Washington, Seattle
$1.2 million

Data from the genome-wide association studies will be deposited in the database of Genotypes and Phenotypes (dbGaP),, at the National Center for Biotechnology Information, a part of the National Library of Medicine at NIH, which will manage the vast amount of genetic, medical and environmental information that emerges from GEI. To encourage rapid research advances, and in keeping with the principles pioneered by the Human Genome Project, all data generated through these initiatives will be made available to researchers, consistent with NIHs data-sharing policy for NIH-supported, genome-wide association studies, which is available on NIHs Office of Extramural Research Genome-Wide Association Studies Web page at

For researchers who want to view genome-wide association data produced by GEI, dbGaP offers two levels of access. The first is open-access, which means the information will be available without restriction on the Internet, and the second is controlled-access, which requires preauthorization for the individual researcher seeking to view it. The open-access section will allow users to view study documents, such as protocols, ques

Contact: Geoff Spencer
NIH/National Human Genome Research Institute

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