Navigation Links
Gene variations linked to lung cancer susceptibility in Asian women
Date:11/11/2012

An international group of scientists has identified three genetic regions that predispose Asian women who have never smoked to lung cancer. The finding provides further evidence that risk of lung cancer among never-smokers, especially Asian women, may be associated with certain unique inherited genetic characteristics that distinguishes it from lung cancer in smokers.

Lung cancer in never-smokers is the seventh leading cause of cancer deaths worldwide, and the majority of lung cancers diagnosed historically among women in Eastern Asia have been in women who never smoked. The specific genetic variations found in this study had not been associated with lung cancer risk in other populations.

Although environmental factors, such as secondhand smoke (also known as environmental tobacco smoke) or exhaust from indoor cooking are likely account for some cases of lung cancer among Asian women who have never smoked, they explain only a small proportion of the disease. To gain a better understanding of lung cancer in Asian female never-smokers, researchers from the National Cancer Institute (NCI), part of the National Institutes of Health, partnered with researchers from several other countries to create the Female Lung Cancer Consortium in Asia to conduct one of the largest genome-wide association studies (GWAS) in female never-smokers to date. GWAS compares DNA markers across the genome between people with a disease or trait to people without the disease or trait.

"This study is the first large-scale genome-wide association study of lung cancer among never-smoking females anywhere in the world," said Qing Lan, M.D., Ph.D., a senior investigator in NCI's Division of Cancer Epidemiology and Genetics, and the leader of the study.

The consortium, whose findings were reported Nov.11, 2012, online in Nature Genetics, c
'/>"/>

Contact: NCI Press Office
ncipressofficers@mail.nih.gov
301-496-6641
NIH/National Cancer Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Variations of a single gene can lead to too much or too little growth, study shows
2. USF researchers identify gene mutation linked to old age hearing loss
3. Sinusitis linked to microbial diversity
4. BUSM/VA Boston Healthcare System investigators identify new gene linked to PTSD
5. Protein involved in DNA replication, centrosome regulation linked to dwarfism, small brain size
6. Gene mutations linked to most cases of rare disorder -- Alternating Hemoplegia of Childhood
7. BGI reports the latest finding on NMNAT1 mutations linked to Leber congenital amaurosis
8. New gene mutations linked to ALS and nerve cell growth dysfunction
9. Viruses linked to algae that control coral health
10. Myelodysplastic syndromes (MDS) linked to abnormal stem cells
11. Low vitamin D levels linked to weight gain in some older women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene variations linked to lung cancer susceptibility in Asian women
(Date:7/23/2014)... a thirsty bird happens upon a vessel of water, but ... water level out of his reach. Not strong enough to ... one at a time until the water level ... the value of ingenuity, the fable demonstrates that cognitive ability ... characterizes crows as pretty resourceful problem solvers. New research conducted ...
(Date:7/23/2014)... Mass. Honey bees, especially the young, are highly ... work together to maintain temperatures within a narrow range. ... biologist at Tufts University,s School of Arts and Sciences, ... excess heat within a hive in process similar to ... blood vessels and skin. , "This study shows ...
(Date:7/23/2014)... NEWPORT, Ore. -- A comprehensive 15-year analysis of the ... of the United States found that their favored feeding ... the threat of injury and mortality. , The researchers ... and San Francisco to slightly different areas at ... most abundant could significantly decrease the probability of ...
Breaking Biology News(10 mins):Smarter than a first-grader? 2Smarter than a first-grader? 3Smarter than a first-grader? 4How honey bees stay cool 215-year analysis of blue whale range off California finds conflict with shipping lanes 215-year analysis of blue whale range off California finds conflict with shipping lanes 315-year analysis of blue whale range off California finds conflict with shipping lanes 4
... OTO EXPO of the American Academy of Otolaryngology Head ... nose, and throat doctors in the world, will convene September ... scientific research sessions, 594 posters, and several hundred instruction course ... for journalists from around the world to cover breaking science ...
... 2010 - Eurofins MWG Operon, an expert in next generation ... GS Junior. The GS Junior is the optimum system for ... one eighth of the capacity of a GS FLX Titanium ... run. As a consequence, the GS Junior adds a higher ...
... This release is available in French ... high electrical conductivity that promise to revolutionize a wide range ... A team of McGill University researchers have now reported ... along one single conductive polymer molecule at a time, a ...
Cached Biology News:2010 AAO-HNSF miniseminars: Tuesday, Sept. 28, 2010 22010 AAO-HNSF miniseminars: Tuesday, Sept. 28, 2010 3Striding towards a new dawn for electronics 2
(Date:7/22/2014)... Terry Baughn, a senior lecturer in mechanical engineering at ... Engineer of the Year by the North Texas section ... ASME has more than 130,000 members in 158 countries ... technology to assist the engineering community, benefiting the world. ... Texas Society of Professional Engineers honors banquet. Baughn retired ...
(Date:7/22/2014)... New York (PRWEB) July 22, 2014 ... world. The heat produced by controlled fission chain reaction ... This steam pressure is used to drive a power- ... approximately 19% of the world’s total electricity production. Nuclear ... to several under construction, planned and proposed nuclear reactor ...
(Date:7/22/2014)... 22, 2014 Automated cell culture systems ... of cell culture. They allow production of optimum cells ... researchers in drug discovery and industries and biopharmaceutical companies. ... production, iPSC research, cryobanking, cell-based assays, and cellular expression ... , Analysts forecast the Global Cell Culture market ...
(Date:7/22/2014)... July 22, 2014 The DNA ... and concise visual representation of history, migration, and culture. ... always regaled by family history stories stemming from Europe. ... the "old country." Pictures and 8mm home movies painted ... of the family, and Steve ordered a test from ...
Breaking Biology Technology:UT Dallas professor receives Engineer of the Year award 2Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 2Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 3Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 2Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 3Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 4DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 2DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 3DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 4
... , Scott Tarpinian , Eppendorf ... , , Introduction , ... used by scientists to amplify large quantities of DNA. Although the reaction , ... any DNA , sequence as a template, amplification of templates ...
... , Main Menu , , , , ... MENUS AND PROGRAMS. PRESS ENTER TO SELECT HIGHLIGHTED CHOICE) Menu items , are chosen ... This confirms choice or input data or changes display to next menu in hierarchy. , ... (press enter) , Position cursor to choose program. , ...
... , , , , , ... The temperature increment, which can be programmed as desired with every , ... a defined value with every cycle. , , ... by changing , the the annealing temperature in succession from higher to ...
Cached Biology Technology:Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 2Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 3Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 4Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 5Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 6Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 7Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 8Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 9Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 10Using the TripleMaster PCR System for Robust Amplification of , GC-Rich DNA Templates 11Mastercycler Gradient Quick Programming Guide 2
Reacti-Bind DNA Coating Solution...
... regulate cell stretching or compression of a ... Computer controlled so you can precisely regulate ... to produce 64 unique strain parameters. ST-160 ... ST-150. Both models are compatible with Nikon, ...
... EasyCount ViaSure Kit is used in conjunction with ... nucleated cells automatically. The ViaSure Staining Reagent ... - Acridine Orange and Ethidium Bromide to identify ... test, while the EasyCount Slide 6 Multi-well ...
... Basic power supply are used for electrophoretic blotting ... accommodates two 7.5 x 10 cm gels and ... Bio-Ice cooling unit, buffer tank, lid with power ... power supply, 100-120 and 220-240 V, provides output ...
Biology Products: