Navigation Links
Gene therapy a step closer to mass production
Date:6/24/2010

learly understood, but it is known that gene transfer is more effective in cells which are actively dividing, e.g. cancer cells.

Dr Aiva Plotniece, Dr Arkadijs Sobolevs and their colleagues at the Latvian Institute then set out to synthesise dozens of different DHP derivative compounds. Dr Plotniece comments: "The great advantage of these compounds is the biologically active 1,4-DHP fragment, which with proper substitution, can show certain biological and physico-chemical properties. During the project we have designed different 1,4-DHPs, which allowed us to establish structure-activity relationships."

The third project partner, the independent Latvian chemical producer Bapeks, contributed its experience of larger-scale synthesis and advised the Latvian Institute researchers on how best to scale up the synthesis methodology. The compounds were then distributed to a number of other research colleagues in Latvia, Finland and Lithuania for further study. At present, project partners feel that the main uses will be in laboratory experiments, and much further research is needed before they can be used for gene transfer in the human body.

Partners in the EUREKA project believe that although more research is needed, the project has been very successful. "It was the first big, important project for us" says Dr Sobolevs. "We have significantly widened the potential uses of self-assembling 1,4-dihydropyridine derivatives into nanomedicine, gene delivery and even into drug delivery systems." The project team found that EUREKA support helped greatly in preparing, managing and reporting the project. It was also through EUREKA that the other partners were introduced to Bapeks.


'/>"/>

Contact: Piotr Pogorzelski
piotr.pogorzelski@eurekanetwork.org
322-777-0979
EUREKA
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. UF oncologists fight leukemia with two-pronged therapy, clinical trials planned
2. McGill team discovers a piece of the puzzle for individualized cancer therapy via gene silencing
3. Making personalized lung cancer therapy a reality in Europe
4. Meta-analysis: Radiotherapy variants improve survival in non-metastatic lung cancer
5. 4-D software helps adjust for breathing when treating lung cancer with radiotherapy
6. Tool allows precise targeting of radiotherapy for cancer radiation therapy
7. Gene therapy sets stage for new treatments for inherited blindness, Penn veterinary researchers say
8. Smoking during radiation therapy for head and neck cancers linked to poorer outcomes
9. JDRF partners with LCT to test encapsulated cell replacement therapy for the treatment of diabetes
10. Concord Medical Enters Agreement to Acquire Four Radiotherapy and Diagnostic Imaging Centers in Hebei Province
11. Lengthening time a drug remains bound to a target may lead to improving diagnostics, therapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene therapy a step closer to mass production
(Date:12/17/2014)... , Dec. 15, 2014 The ... make it easier to detect and prevent counterfeit ... Today the agency started performing an in-house ... will validate the authenticity of purchased microcircuits while ... new quality control measures will be conducted at ...
(Date:12/17/2014)... Research and Markets ( http://www.researchandmarkets.com/research/9zq33j/global_chemical ... "Global Chemical Sensor Market 2015-2019" report to ... One major trend upcoming in ... sensors in biomedical applications. Chemical sensors help in ... diagnosis during surgical procedures. The Global Chemical Sensor ...
(Date:12/11/2014)... DUBLIN , Dec. 09, 2014 Research ... http://photos.prnewswire.com/prnh/20130307/600769 ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) ... Market in the APAC Region 2015-2019"  report to ... emerging in this market is advances in technology. ... to upgrade biometric solutions to the latest standard ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... Paul Flecknell, PhD, widely recognized for his expertise in ... is the 2009 recipient of the Charles River Laboratories, ... on September 3 at the 7th World Congress on ... Rome. Sponsored by Charles River Laboratories, in cooperation ...
... physicians hope to provide earlier diagnoses and improve therapy ... study emphasizes, the first step must be to ,correctly ... and determine its impact on human health. In ... Sudhir Kumar led a team of researchers at the ...
... one of the nation,s premiere tools in the fight against ... depleted oil and natural gas reservoirs, can be used to ... gas. CO2 would be captured at coal burning power plants, ... by pipeline to reservoirs where it would be pumped for ...
Cached Biology News:Species diversity helps ASU researchers refine analyses of human gene mutations 2Species diversity helps ASU researchers refine analyses of human gene mutations 3Department of Energy supports carbon sequestration research, University of Miami receives $1.7 million 2
(Date:12/17/2014)... Ipsen Biopharmaceuticals, Inc., an affiliate ... IPSEY), today announced that Somatuline® Depot® (lanreotide) ... approved by the U.S. Food and Drug Administration ... (GEP-NETs) in adult patients with unresectable, well or ... improve progression-free survival (PFS). , “The approval of ...
(Date:12/17/2014)... This report is a professional and ... an overview analysis, the report introduces quartz tubing ... industry overview, policy analysis, and news analysis, etc. ... witnessed rapid development with key manufacturers increasing their ... mentions quartz tubing upstream raw materials and equipment, ...
(Date:12/17/2014)... Gene synthesis and bioengineering company ... into a technology access and services agreement with ... proprietary protein engineering technology, known as “ProteinGPS®” to ... extremely excited that the global leader ADM has ... bioengineering technology has now been validated through many ...
(Date:12/17/2014)... 16, 2014  Vermillion, Inc. (NASDAQ: VRML ... today announced the next step in its expanded strategy ... provider with the naming of current Chief Operating Officer, ... Officer, while current Chairman of the Board and CEO ... Chairman. These changes are effective January 1, 2015. ...
Breaking Biology Technology:Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 2Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 3Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 4Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 5Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 6Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 7Ipsen Announces the FDA Approval of Somatuline® Depot® (lanreotide) Injection for the Treatment of Gastroenteropancreatic Neuroendocrine Tumors 82020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4
... 7 /PRNewswire-FirstCall/ - GeneNews Limited (TSX: GEN), a,company ... early,detection of diseases and personalized health management, today ... and year to date,ended June 30, 2008., ... a blood,test to assess a patient,s current risk ...
... Grease Reduction Systems, Inc announces the world,s first commercially ... first installed at a luxury resort, Montage Laguna Beach. ... ... 7, 2008 -- http://www.greasereduction.com [Grease Reduction Systems, Inc ...
... Robert N. Butler, M.D., has been elected to ... founder, Chief Executive Officer, and President of the ... and education organization formed to educate individuals on ... society on how to maximize the benefits of ...
Cached Biology Technology:GeneNews Announces Second Quarter Results 2GeneNews Announces Second Quarter Results 3GeneNews Announces Second Quarter Results 4GeneNews Announces Second Quarter Results 5GeneNews Announces Second Quarter Results 6GeneNews Announces Second Quarter Results 7GeneNews Announces Second Quarter Results 8Grease Reduction System a Break Through in Truly "Green" Technology for Luxury Resort 2Grease Reduction System a Break Through in Truly "Green" Technology for Luxury Resort 3 Dr. Robert N. Butler Appointed to Board of Directors of BioTime, Inc. 2 Dr. Robert N. Butler Appointed to Board of Directors of BioTime, Inc. 3 Dr. Robert N. Butler Appointed to Board of Directors of BioTime, Inc. 4
Rabbit polyclonal to Staphylococcus Enterotoxin A (HRP) ( Abpromise for all tested applications)....
Custom LNA Oligonucleotide synthesis ,High quality Custom LNA Oligonucleotides are available for a variety of different specialty applications and innovative products. ,Please inquire for further...
... Plus is a chemiluminescent signal enhancing ... to boost the signal obtained with ... kits. ChemiLucent™ Plus is derived from ... conjugated complex- or chemiluminescent substrate enhancers, ...
... Multi-Disciplinary Team The Schleicher & ... stand-alone work center dedicated to custom ... The facilitys experienced project teams, comprised ... Marketing professionals, work closely with collaborators ...
Biology Products: