The mice did not readily get restful sleep even after sleep deprivation, the researchers found.
In future studies, the researchers hope to focus on the Kv3.1 mutation alone, which they believe, based on previous studies might be the primary factor in the sleep disturbances, while Kv3.3 mutations might affect muscle coordination.
The researchers also plan to investigate ways to restore function of Kv3.1 with potential drugs. So far, there are no medications that affect this ion channel.
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| Contact: Aline McKenzie aline.mckenzie@utsouthwestern.edu 214-648-3404 UT Southwestern Medical Center Source:Eurekalert |