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Gene mutations in mice mimic human-like sleep disorder, UT Southwestern researchers find
Date:5/20/2008

ow-wave sleep, but only for short periods before waking again.

The mice did not readily get restful sleep even after sleep deprivation, the researchers found.

In future studies, the researchers hope to focus on the Kv3.1 mutation alone, which they believe, based on previous studies might be the primary factor in the sleep disturbances, while Kv3.3 mutations might affect muscle coordination.

The researchers also plan to investigate ways to restore function of Kv3.1 with potential drugs. So far, there are no medications that affect this ion channel.


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Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
Source:Eurekalert  

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Gene mutations in mice mimic human-like sleep disorder, UT Southwestern researchers find
Gene mutations in mice mimic human-like sleep disorder, UT Southwestern researchers find
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