Navigation Links
Gene mutation immortalizes malignant melanoma
Date:1/25/2013

lways seems to have been overlooked," says Kumar.

Rajiv Kumar, Dirk Schadendorf and their teams are hoping that the alterations in the telomerase gene may be a starting point for developing novel treatment methods for malignant melanoma. A very recent development targeting a specific alteration in the B-RAF gene, which characterizes about half of all melanomas, has shown that this is possible. The mutation gave rise to the development of a targeted drug that can arrest cancer growth. "Substances inhibiting telomerase have already been developed and some of them have even been tested in phase III clinical trials," said Rajiv Kumar. Inhibition of the immortality enzyme might also be able to arrest growth in melanoma.


'/>"/>

Contact: Sibylle Kohlstdt
s.kohlstaedt@dkfz.de
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers attack HIVs final defenses before drug-resistant mutations emerge
2. EGFR mutation not prognostic factor in non-small cell lung cancer
3. Architecture of rod sensory cilium disrupted by mutation
4. Duke Medicine news -- Genome sequencing of Burkitt Lymphoma reveals unique mutation
5. Mutations in genes that modify DNA packaging result in Facioscapulohumeral Muscular Dystrophy
6. USF researchers identify gene mutation linked to old age hearing loss
7. Chinese scientists discover MVK mutations associated with DSAP
8. Study reveals how common gene mutation affects kids with autism spectrum disorders
9. Most mutations come from dad
10. Populations survive despite many deleterious mutations
11. New method provides fast, accurate, low cost analysis of BRCA gene mutations in breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/12/2014)... Nov. 12, 2014 Crossmatch™, a leading provider ... U.are.U ® fingerprint readers have been deployed throughout ... Central Mexico . The bakery chain implemented ... payroll issues caused by employees clocking in for each ... fingerprint readers, Montparnasse relied on paper timecards and a ...
(Date:11/10/2014)... store shelves in early 2010, and people have used ... can be tossed into a washing machine without ever ... convenience, though, has come with risks for young children. ... Hospital found that from 2012 through 2013, U.S. poison ... 6 years of age swallowing, inhaling, or otherwise being ...
(Date:11/7/2014)... , Nov. 7, 2014  In conjunction with the ... Police Departments, The Community Foundation of the Verdugos has ... DNA JUSTICE PROJECT," a $250,000 initiative to keep the ... phase. In its first six months of existence, the Lab ... evidence support for local law enforcement. "Because our ...
Breaking Biology News(10 mins):Montparnasse Pasteleria Achieves Time and Attendance Transparency with Crossmatch U.are.U Fingerprint Readers 2Study finds laundry detergent pods, serious poisoning risk for children 2Community Foundation Of The Verdugos Unveils Campaign To Fund Glendale-Burbank DNA Justice Project 2
... Southwestern Medical Center have found an enzyme vital for controlling ... process when it works right, but malignant in a variety ... examining tissue from cancer patients to try to determine how ... “We think this gene will really be a hot spot ...
... to find alternative fuel sources are lighting a fire under ... , Texas Senate Bill 20, signed this week by Gov. ... biomass can be used. The new law requires more renewable ... years. , Combining consumer energy needs and agriculture industry trends ...
... by biologists at the University of California, Berkeley, has found ... reaction that leads to the increased expression of a marker ... to be published July 3 in an advanced online issue ... the natural killer (NK) cells - which are able to ...
Cached Biology News:UT Southwestern researchers discover master switch in cell death 2Researchers find ways to turn manure into power 2Researchers find ways to turn manure into power 3New study finds how cells with damaged DNA alert the immune system 2New study finds how cells with damaged DNA alert the immune system 3
(Date:11/24/2014)... 2014 2014 Deep Research Report ... a professional and in-depth research report on the ... like its definition, classification, application, and industry chain ... covers the international market analysis, including China’s domestic ... US, Europe, Asia, China, Japan etc. regions) industry ...
(Date:11/22/2014)... London (PRWEB) November 21, 2014 Two new ... explore what comes next for ALS research and how the ... , After the Ice Bucket Challenge: Where Does the ALS ... Tuesday, 2 December 2014, Time: 1:30pm ET, ... Join expert speaker Dr. Merit Cudkowicz, Julianne Dorn Professor of ...
(Date:11/22/2014)... Chicago, IL (PRWEB) November 21, 2014 ... technology competitors at the 2014 Emerging Medical Technologies Summit ... MedTech Innovator Awards. Widely regarded among Silicon Valley ... emerging medical device innovation, the win also positions Briteseed ... the MedTech Innovator competition in 2015 and compete with ...
(Date:11/21/2014)... 21, 2014 , Todd ... Mariano Rodríguez es elegid vicepresidente senior de ... KLOX está en marcha para comenzar de forma rápida la ... de reciente aprobación en Europa   , ... al anunciar los siguientes nombramientos: Todd Martensen ...
Breaking Biology Technology:Adipic Dihydrazide Industry 2019 Research Forecasts on Worldwide, China Regions Now Available at ReportsnReports.com 2Adipic Dihydrazide Industry 2019 Research Forecasts on Worldwide, China Regions Now Available at ReportsnReports.com 3DrugDev Webinars in December to Explore What Comes Next for ALS Research and How We Can Make Life Easier for Clinical Sites 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 3KLOX Technologies anuncia sus nombramientos ejecutivos 2KLOX Technologies anuncia sus nombramientos ejecutivos 3KLOX Technologies anuncia sus nombramientos ejecutivos 4KLOX Technologies anuncia sus nombramientos ejecutivos 5
... Md., Aug. 17 Novavax, Inc. (Nasdaq: ... the company will be presenting at the IMVAC Summit. ... the Royal Sonesta Hotel, Cambridge, MA.  Dr. Steven Pincus ... Insect Cells Elicits Hemagglutination and Neuraminidase Inhibiting Antibodies in ...
... In experiments with potentially broad health care implications, a ... has devised a method that works at a very ... That could open the door for more effective ... for specific conditions and diseases such as cancer, diabetes ...
... DCTH ) (the "Company"), today announced the sale of ... with Canaccord Genuity acting as the sole bookrunner.  The last reported ... Nasdaq Capital Market on August 16, 2010 was $7.15 per share. ... from the sale of the shares for funding of its clinical ...
Cached Biology Technology:NOVAVAX to Present at the Immunotherapeutics and Vaccine (IMVAC) Summit 2Nanoscale DNA sequencing could spur revolution in personal health care 2Delcath Systems Announces the Sale of 5,185,000 Shares of Common Stock 2Delcath Systems Announces the Sale of 5,185,000 Shares of Common Stock 3
... Round Well Plate Sterile ... wide range of 384-well ... high-throughput screening and research. ... assays and are suitable ...
Request Info...
Aldolase A (N-15)...
Bovine Aortic Smooth Muscle Cells (BAOSMC) (>500,000 cells)...
Biology Products: