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Gene expression findings a step toward better classification and treatment of juvenile arthritis
Date:6/29/2009

a positive ANA, than to the other subgroups of polyarticular JIA.

Dr. Colbert says the new findings take pediatric rheumatologists a step closer to more precisely classifying JIA, and eventually developing individually tailored treatments that maximize the benefits, while minimizing the risks. "In pediatric rheumatology, we are at the early stages of improving our classification system for JIA. We expect that complementary studies designed to uncover the genetic differences that contribute to susceptibility will confirm the presence of several JIA subtypes, and add important information about what causes this group of diseases," he said. "We look forward to the day when we can use a combination of genetic and gene expression tests in the clinic to help us better diagnose and treat childhood arthritis."


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Contact: Trish Reynolds
reynoldsp2@mail.nih.gov
301-496-8190
NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
Source:Eurekalert

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