Navigation Links
Gene discovery could lead to male contraceptive
Date:4/2/2009

A newly discovered genetic abnormality that appears to prevent some men from conceiving children could be the key for developing a male contraceptive, according to University of Iowa researchers reporting their findings in the April 2 online edition of the American Journal of Human Genetics.

Although female oral contraceptives were developed over 40 years ago and have proven very effective for family planning, no similar pharmacological contraceptive has been developed for males. Surveys conducted by the Medical Research Council Reproductive Biology Unit in the United Kingdom, suggest that men would be willing to use a pharmacological contraceptive if one was available. Presently the only contraceptives available for men are condoms or a vasectomy.

"We have identified CATSPER1 as a gene that is involved in non-syndromic male infertility in humans, a finding which could lead to future infertility therapies that replace the gene or the protein. But, perhaps even more importantly, this finding could have implications for male contraception," said Michael Hildebrand, Ph.D., co-lead author of the study and a UI postdoctoral researcher in otolaryngology at the UI Roy J. and Lucille A. Carver College of Medicine.

The research team, which included scientists from the University of Social Welfare and Rehabilitation Sciences in Tehran, Iran, discovered the male infertility gene while studying the genetics of families from Iran -- a population that has relatively high rates of disease-causing gene mutations.

Although the team's research with these Iranian families focuses on identifying genetic causes of deafness, collecting genetic information from this population allowed the researchers to identify two families where male infertility that was not part of a syndrome appeared to be inherited. The affected men's infertility was diagnosed with a routine semen analysis.

Focusing on a group of genes that have been implicat
'/>"/>

Contact: Jennifer Brown
jennifer-l-brown@uiowa.edu
319-335-9917
University of Iowa
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Bioscience institutions come together to launch Microlife Discovery Center for area students
2. Teeth of Columbus crew flesh out tale of new world discovery
3. Elephant shark genome sequence leads to discovery of color perception in deep-sea fish
4. Cellular discovery may lead to targeted treatment for rare form of anemia
5. New discovery paves the way for new diagnosis of serious lung disease
6. La Jolla Institute signs exclusive license agreement with Medimmune on major asthma discovery
7. Rett Syndrome Research Trust advisor makes significant discovery
8. Singapore research organisations team up to advance drug discovery using brain tumor stem cells
9. Breaking the barrier: Discovery of anti-resistance factors and novel ocean drugs
10. Major step for drug discovery and diagnostics
11. Cell-building discovery could reduce need for some animal research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Gene discovery could lead to male contraceptive
(Date:4/20/2015)... April 20, 2015 Huntington Memorial Hospital is ... implant a new miniaturized, wireless monitoring sensor to manage ... first and only FDA-approved heart failure monitoring device that ... used by physicians to manage heart failure. ... implanted in the pulmonary artery (PA) during a non-surgical ...
(Date:4/20/2015)... DUBAI , April 20, 2015 ... soars   Glenbeigh Records Management (GRM), ... contract with Dubai Islamic Bank. Having built up an impressive ... is now a leading player within the records management sector ... company expects to double is GCC staffbase and employ a ...
(Date:4/17/2015)... April 17, 2015 ... and technological advancement to drive biometric systems market ... 2020   According to a recently ... Systems Market Forecast &  Opportunities, 2020 ", biometric systems market in ... register growth at CAGR of over 22% through ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3
... awarded the Outstanding Crop Scientist Award by the International ... scientists to receive the award in recognition of lifetime ... He also chaired a special international workshop for the ... Breeding of Climate Resilient Crops for Future Food Security." ...
... nanomaterials--now popular in consumer products such as shampoos, gels, ... and yield of food crops, as reported in a ... the National Academy of Sciences . Manufactured nanomaterials ... atomic and molecular scale. Their effects on human health ...
... used in the service of science today. They serve as ... as therapeutic viruses targeted to infect and destroy cancer cells. ... genes, such as for immune mediators or for proteins inducing ... body if they are released at the wrong moment or ...
Cached Biology News:Soybeans susceptible to man-made materials in soil 2Soybeans susceptible to man-made materials in soil 3Viruses with integrated gene switch 2
(Date:4/21/2015)... (PRWEB) April 21, 2015 Contract Research Organization ... plans to relocate into a new 41,500 ft2 facility. ... headquarters, currently located at 16825 W. 116th St. in Lenexa, ... half times the customized laboratory space, will remain in the ... company was founded more than twenty years ago. Remaining ...
(Date:4/21/2015)... 2015 Staying true to their mission ... digital product that makes the world a better place, ... Standards Institute (GBSI) to redesign their website ( http://www.gbsi.org ... importantly, strategy-based. , "Biomedical research is not always an ... to promote it in a narrative way on a ...
(Date:4/21/2015)... April 21, 2015  Scientists from the J. ... organization, published a paper today outlining new synthetic ... called diatoms. The researchers, led by first author ... Philip Weyman , Ph.D., conclude that these ... of diatom genetics and thus facilitate advances in ...
(Date:4/21/2015)... , April 21, 2015 AbilTo, Inc., ... that its abstract submission has been accepted as a ... (ADA) annual meeting taking place on June 5-6, 2015 in ... According to the American Diabetes Association, the cost of ... $245 billion. As a result of increased inpatient, outpatient, ...
Breaking Biology Technology:XenoTech Plans Expansion to New Global Headquarters after Impressive Revenue Growth in 2014 2XenoTech Plans Expansion to New Global Headquarters after Impressive Revenue Growth in 2014 3Visceral Tells GBSI’s Story Within 30 Seconds of Attention 2Visceral Tells GBSI’s Story Within 30 Seconds of Attention 3Scientists at the J. Craig Venter Institute Publish Paper Outlining Efficient Synthetic Biology Methods to Genetically Engineer Microalgae 2Scientists at the J. Craig Venter Institute Publish Paper Outlining Efficient Synthetic Biology Methods to Genetically Engineer Microalgae 3AbilTo To Present at the 2015 American Diabetes Association Annual Meeting on Remote Delivery of Behavioral Change Therapy 2AbilTo To Present at the 2015 American Diabetes Association Annual Meeting on Remote Delivery of Behavioral Change Therapy 3
... STAAR Surgical Company (Nasdaq: STAA ), a ... products, today announced that it has received CE Mark ... use in minimally invasive cataract surgical procedures. The ... intraocular (IOL) KS-X lens delivery system in the European ...
... ... Matrix Genomics, Inc. have identified a concise genetic signature found among a third of Parkinson,s ... is found in the LRRK2 gene located on chromosome 12. The work was led by ... ...
... Bioscience International, a leader in enabling and accelerating the ... China, today announced a strategic drug co-development partnership with ... range of therapeutic areas and represents one of the ... biotech company and a Chinese university. , , ...
Cached Biology Technology:STAAR Surgical Receives CE Mark Approval for KS-X Preloaded Hydrophobic Acrylic Lens Injector System 2STAAR Surgical Receives CE Mark Approval for KS-X Preloaded Hydrophobic Acrylic Lens Injector System 3STAAR Surgical Receives CE Mark Approval for KS-X Preloaded Hydrophobic Acrylic Lens Injector System 4Matrix Genomics, Elizabeth Corder, PhD - Gene Variation in the LRRK2 Gene and High Risk for Parkinson's Disease 2Matrix Genomics, Elizabeth Corder, PhD - Gene Variation in the LRRK2 Gene and High Risk for Parkinson's Disease 3HUYA Bioscience Announces Strategic Collaboration With the Shenyang Pharmaceutical University 2HUYA Bioscience Announces Strategic Collaboration With the Shenyang Pharmaceutical University 3
... maximum performance on minimum space. Thanks to ... heating and cooling rates have been achieved ... a maximum capacity of 48 x 0.2ml ... of much more expensive 96 well instruments. ...
Sf21 Insect Cells (Live) in Max-XP Medium...
Dual-bay Dyad thermal cycler chassis, does not include the Alpha units (requires 2)...
EZ-DeWax is a one-step solution that simultanously removes paraffin from and rehydrates formalin-fixed, paraffin embedded tissue...
Biology Products: