Navigation Links
Gene determines whether male body odor smells pleasant
Date:9/16/2007

ll.

Although it has long been suspected that the ability to perceive the odor of androstenone is genetically determined, this study is the first to identify variations in a single gene that account for a large part of why people perceive androstenone's scent so differently.

With their Duke collaborators, Vosshall and Keller identified two point mutations called single nucleotide polymorphisms along the gene, which gave rise to two variants of the odorant receptor: RT and WM, which differ by two amino acids. As a group, participants with the RT/RT genotype perceive androstenone's odor as foul and intense. Those with the RT/WM genotype, on the other hand, are more likely to perceive androstenone as less unpleasant. Many cannot smell androstenone at all. Although some participants with the RT/WM genotype can smell androstenone, they experience the smell very differently than those with two copies of the fully functional receptor: To them, androstenone doesn't smell like urine; it has a vanilla scent.

"There are two independent things that are interesting about this odor," says first co-author Keller. "One is that it is a potential social signal but the other one is that so many people cannot smell it."

Two additional point mutations in some of the participants influenced their sensitivity to androstenone, one of which may make humans hypersensitive to this odor. Vosshall and Keller are interested in what it is about these amino acid changes that alter one's perception of androstenone's scent, and in whether one's perception of this potent compound can influence behavior.

"Since some mammals clearly use androstenone to communicate sexuality and dominance within a social hierarchy, it's intriguing to think whether the same thing may happen in humans," Vosshall says. "If so, what happens to humans who can't get the signal because they have the nonfunctional copy of the gene" Or the hyperfunctional one" What could be the soci
'/>"/>

Contact: Thania Benois
tbenois@rockefeller.edu
212-327-7146
Rockefeller University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Newly-discovered class of genes determines ?and restricts ?stem cell fate
2. International Team Determines Geographic Origin of Leprosy
3. Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation
4. Weapon performance determines mating success in the collared lizard
5. Genetic tug of war determines sexual differentiation
6. Researchers discover mechanism that determines when detailed memories are retained
7. Gene controls whether fear is a factor
8. Human preference for other species could determine whether they survive
9. Racing neurons control whether we stop or go
10. Neuroscientists discover new cell type that may help brain maintain memories of smells
11. Researchers show how brain decodes complex smells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/11/2014)... Research and Markets , ... announced the addition of the "Biometrics Market in ... One major trend emerging in this market is ... utilize more than one characteristic of an individual for ...
(Date:12/10/2014)... , Dec. 8, 2014 You,ve been here before: you desperately ... your password, site key or the answer to your secret question. ... Today, Hoyos Labs , a digital infrastructure security ... end to the frustration that comes with usernames, passwords and PINs ...
(Date:12/10/2014)... SAN DIEGO , Dec. 9, 2014 CIE San ... that provides the connective tissue that enhances care coordination among ... share client-level information; earned a second $1 million grant from ... aging in community and; will be recognized as a "Live ...
Breaking Biology News(10 mins):Biometrics Market in India 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... biological weapons are created equal. They are separated into ... the scariest: They are easy to spread, kill effectively ... system. One of these worrisome organisms is anthrax, which ... But work in Vince Fischetti's laboratory at Rockefeller University ...
... National Institute of Allergy and Infectious Diseases (NIAID), ... today announced that enrollment into a large international ... drug treatment guided by levels of CD4+ cells ... patients receiving episodic therapy had twice the risk ...
... Scientists at Karolinska Institutet in Sweden have helped to ... vaccination agent against growing cancer tumours. Although the results ... to new methods of treating metastases. , The results ... scientific journal Nature Medicine, and represent the collaborative efforts ...
Cached Biology News:Newly discovered protein kills anthrax bacteria by exploding their cell walls 2International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy 2International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy 3International HIV/AIDS trial finds continuous antiretroviral therapy superior to episodic therapy 4
(Date:12/24/2014)... 23, 2014 GMO corn cases filed across ... in the process of being consolidated in a Kansas federal ... Syngenta AG MIR 162 Corn Litigation, MDL No. 2591 in ... Management of the Syngenta GMO corn multidistrict litigation (MDL) has ...
(Date:12/24/2014)... SoundConnect’s 2015 next ... edge communication technology, provide continued education and inform ... series demonstrates online communication features and benefits; empowering ... most innovative and powerful tools. , According to ...
(Date:12/24/2014)... Long Island, New York (PRWEB) December 23, 2014 ... , and the Long Island Affiliate of ITRA Global, the ... economy’s slow but steady recovery. This is evidenced by ... and the strong stock market. Low energy costs have ...
(Date:12/24/2014)... 23, 2014 Nashville Fertility Center announced that ... the American Society for Reproductive Medicine (ASRM), a leading professional ... In his new role as treasurer, Dr. Hill also ... a voice in furthering the mission of ASRM. , ...
Breaking Biology Technology:Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3
... (Amex: PTN ) announced today financial results for ... net loss of $247,000, or $0.00,per basic and diluted ... a net loss of $8.4 million, or ($0.12) per ... Total revenues for the quarter ended,September 30, 2007 were ...
... 9 at 8:00 a.m. PST -, SAN ... HALO ), a biopharmaceutical company developing and commercializing,products ... for the three and nine months ended September ... the complexities of the,extracellular matrix provide a number ...
... 8 Kosan Biosciences,Incorporated (Nasdaq: KOSN ) today reported ... 2007. Net loss for the quarter and nine months ... $0.26 per share and $0.46 per share,compared to a net ... per share, in the same periods last year. Revenues ...
Cached Biology Technology:Palatin Technologies, Inc. Reports Fiscal Year 2008 First Quarter Results; Teleconference and Webcast to be Held on November 9, 2007 2Palatin Technologies, Inc. Reports Fiscal Year 2008 First Quarter Results; Teleconference and Webcast to be Held on November 9, 2007 3Palatin Technologies, Inc. Reports Fiscal Year 2008 First Quarter Results; Teleconference and Webcast to be Held on November 9, 2007 4Palatin Technologies, Inc. Reports Fiscal Year 2008 First Quarter Results; Teleconference and Webcast to be Held on November 9, 2007 5Palatin Technologies, Inc. Reports Fiscal Year 2008 First Quarter Results; Teleconference and Webcast to be Held on November 9, 2007 6Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 2Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 3Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 4Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 5Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 6Kosan Announces Third Quarter 2007 Financial Results 2Kosan Announces Third Quarter 2007 Financial Results 3Kosan Announces Third Quarter 2007 Financial Results 4Kosan Announces Third Quarter 2007 Financial Results 5Kosan Announces Third Quarter 2007 Financial Results 6Kosan Announces Third Quarter 2007 Financial Results 7
E2F2 protein...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
... Goat polyclonal to Cholesterol Oxidase ... / Specificity Cross-reacts with bacteria. Not ... Information Cholesterol oxidases exist as both ... are implicated in bacterial pathogenesis. In addition, ...
Phospho-PERK (Thr980) Antibody...
Biology Products: