Navigation Links
Gene determines whether male body odor smells pleasant
Date:9/16/2007

ll.

Although it has long been suspected that the ability to perceive the odor of androstenone is genetically determined, this study is the first to identify variations in a single gene that account for a large part of why people perceive androstenone's scent so differently.

With their Duke collaborators, Vosshall and Keller identified two point mutations called single nucleotide polymorphisms along the gene, which gave rise to two variants of the odorant receptor: RT and WM, which differ by two amino acids. As a group, participants with the RT/RT genotype perceive androstenone's odor as foul and intense. Those with the RT/WM genotype, on the other hand, are more likely to perceive androstenone as less unpleasant. Many cannot smell androstenone at all. Although some participants with the RT/WM genotype can smell androstenone, they experience the smell very differently than those with two copies of the fully functional receptor: To them, androstenone doesn't smell like urine; it has a vanilla scent.

"There are two independent things that are interesting about this odor," says first co-author Keller. "One is that it is a potential social signal but the other one is that so many people cannot smell it."

Two additional point mutations in some of the participants influenced their sensitivity to androstenone, one of which may make humans hypersensitive to this odor. Vosshall and Keller are interested in what it is about these amino acid changes that alter one's perception of androstenone's scent, and in whether one's perception of this potent compound can influence behavior.

"Since some mammals clearly use androstenone to communicate sexuality and dominance within a social hierarchy, it's intriguing to think whether the same thing may happen in humans," Vosshall says. "If so, what happens to humans who can't get the signal because they have the nonfunctional copy of the gene" Or the hyperfunctional one" What could be the soci
'/>"/>

Contact: Thania Benois
tbenois@rockefeller.edu
212-327-7146
Rockefeller University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Newly-discovered class of genes determines ?and restricts ?stem cell fate
2. International Team Determines Geographic Origin of Leprosy
3. Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation
4. Weapon performance determines mating success in the collared lizard
5. Genetic tug of war determines sexual differentiation
6. Researchers discover mechanism that determines when detailed memories are retained
7. Gene controls whether fear is a factor
8. Human preference for other species could determine whether they survive
9. Racing neurons control whether we stop or go
10. Neuroscientists discover new cell type that may help brain maintain memories of smells
11. Researchers show how brain decodes complex smells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... Mass. (September 15, 2014) The so-called central ... makes proteinhas long provided a simplified explanation for ... living organisms. , In reality, of course, ... schema first articulated nearly 60 years ago by ... double-helix structure. For one, there are multiple types ...
(Date:9/15/2014)... both plants and animals alike. , Understanding just how ... to the design of better drugs for diabetes patients ... vegetables farmers are able to grow. Stanford University researchers ... cell by piecing together proteins slightly wider than the ... determine the size, shape and orientation of one of ...
(Date:9/15/2014)... will allow us to better understand how the ... scenarios and provide the type of environmental data ... and siting of protected areas," said Paula Whitfield, ... Coastal Ocean Science (NCCOS) and lead author of ... within the temperate-tropical transition zone, where historically, both ...
Breaking Biology News(10 mins):Scientists discover RNA modifications in some unexpected places 2X-rays unlock a protein's SWEET side 2X-rays unlock a protein's SWEET side 3Study finds warming Atlantic temperatures could increase range of invasive species 2
... D.C., November 21, 2010 -- For centuries, hunters have imitated ... carving wooden bird calls. Now a team of physicists at ... characteristics of real bird song with a simple physical model ... know if you [could] build a simple device, which has ...
... baby,s first blurted "bowl!," for the word "ball" to the ... vocalizations is one of humankind,s most remarkable attributes -- and ... Not so for people who are afflicted with ... stigma of affected speech. Nor so for engineering professor Michael ...
... , Researchers in the United States have developed a ... from a patient,s own bone marrow. The research, published ... suffering from abnormally developed bladders, but also represents another ... research, led by Dr Arun Sharma and Earl Cheng ...
Cached Biology News:Simple rubber device mimics complex bird songs 2Air flows in mechanical device reveal secrets of speech pathology 2New study into bladder regeneration heralds organ replacement treatment 2
(Date:9/16/2014)... In preparation for VARTECH 2014, 2FA, Inc., ... focused on authentication and SSO announced today that their ... generate a OTP through the presentation of an RFID ... RFID authentication, 2FA,s solutions have leveraged the existence of ... RFID authentication is broadly deployed in healthcare and other ...
(Date:9/15/2014)... Sept. 15, 2014   Global Science & ... scientific products and services for satellite and weather ... for Integrated Services (OASIS) from the General Services ... selected to provide the government best-value solutions for ... (SB) category in Pool 4. The OASIS SB ...
(Date:9/15/2014)... a patient has sepsis, a life-threatening condition in which ... often too fast for antibiotics to help. A new ... a team at Harvard,s Wyss Institute for Biologically Inspired ... , "Even with the best current treatments, sepsis ... 30 percent of the time," said Mike Super, Ph.D., ...
(Date:9/15/2014)...  iVinci Health LLC, the company behind the healthcare ... branded as VisitPay®, has successfully closed $5 million in ... a new extension to VisitPay® – an online Payment ... way for patients to manage their medical bills and ... their families. The new round of funding, ...
Breaking Biology Technology:2FA, Inc. Announces RFID-based One-Time Password (OTP) Authentication 2Global Science & Technology, Inc. Awarded GSA OASIS Small Business Contract 2Global Science & Technology, Inc. Awarded GSA OASIS Small Business Contract 3Blood-cleansing biospleen device developed for sepsis therapy 2Blood-cleansing biospleen device developed for sepsis therapy 3Blood-cleansing biospleen device developed for sepsis therapy 4iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 3
... FRANCISCO, Calif., Nov. 1, 2010 diaDexus, Inc. (OTC ... focused on the development and commercialization of patent-protected ... cardiovascular disease, today announced that the company, formerly known ... Board under the ticker symbol (VXGN), has been renamed ...
... Nov. 1, 2010 Amgen (Nasdaq: AMGN ) ... Ph.D., will urge members of a U.S. Food and Drug ... to establish approval standards that ensure patient safety and follow ... policy will follow," Dr. Miletich said.  "Amgen believes biosimilars have ...
... ... ... var shortURL = ""; BitlyCB.alertResponse = function(data) ... first one. for (var r in data.results) { first_result = data.results[r]; break; } for (var key in first_result) { ...
Cached Biology Technology:diaDexus Announces Name Change From VaxGen 2diaDexus Announces Name Change From VaxGen 3Amgen to Provide Testimony at FDA Hearing on Biosimilars 2Amgen to Provide Testimony at FDA Hearing on Biosimilars 3Amgen to Provide Testimony at FDA Hearing on Biosimilars 4NEURO-BIOTECH CORPORATION: Updates and latest developments 2NEURO-BIOTECH CORPORATION: Updates and latest developments 3NEURO-BIOTECH CORPORATION: Updates and latest developments 4NEURO-BIOTECH CORPORATION: Updates and latest developments 5NEURO-BIOTECH CORPORATION: Updates and latest developments 6NEURO-BIOTECH CORPORATION: Updates and latest developments 7NEURO-BIOTECH CORPORATION: Updates and latest developments 8NEURO-BIOTECH CORPORATION: Updates and latest developments 9
Request Info...
...
... High Resolution - Efficiently ... 50 to 1000 bp. ... sizing PCR fragments, small ... restriction enzyme digestion, and ...
... ZMD.358. Immunogen: Synthetic peptide ... of human mouse and rat ... human and mouse LRP5 proteins. ... controls: mouse LRP5-pSEC-tag-transfected 293T cells ...
Biology Products: