Navigation Links
Gender-specific disease risks start in the womb
Date:5/6/2010

Pregnancy places competing demands on a mother's physiology: Her body wants to produce a strong healthy baby but not at the expense of her own health. Some of the genes that she passes on to her child therefore try to protect her own body from excessive demands from her child. These so-called "imprinted genes" inherited from the father however do not show the same restraint their goal is to get as many resources for the fetus as possible. Evidence that this battle of the imprinted genes might be at the root of later life disease processes will be presented at the International Conference The Power of Programming in Munich on 6 to 8 May, organised by the EC-funded Early Nutrition Programming Project (EARNEST).

"The imprinted genes derived from the father are greedy whilst those from the mother are conservative in their needs to ensure future reproductive success", said Dr. Miguel Constancia from the University of Cambridge, England. "We have found evidence that imprinted genes play important roles in the control of endocrine functions of the placenta. These placental adaptations have marked effects on nutrient delivery to the fetus, resulting in the programming of homeostatic mechanisms with metabolic consequences extending to adulthood, for example for type 2 diabetes susceptibility."

There is evidence that some programming effects are different in male and female offspring. Dr. Rachel Dakin from the University of Edinburgh, Scotland, shows how maternal obesity is associated with sex-specific programming effects in young adult mice. Female offspring of obese mothers had raised blood insulin levels, whilst male offspring did not. Male offspring did have alterations in the expression of liver genes important in lipid and glucocorticoid metabolism.

Professor Claudine Junien from the Institut National de Recherche Agronomique (INRA) in France says: "For me a gene, a cell and even a sex does not think and has no intelligent design. Inste
'/>"/>

Contact: Rhonda Smith or Marc Catchpole
info@minervaprc.com
44-126-471-0428
Ludwig-Maximilians-Universitt Mnchen
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Endometrial stem cells could repair brain cells damaged by Parkinsons disease
2. Sequencing of first frog genome sheds light on treating disease
3. Young people with inflammatory bowel diseases are at increased risk of fracture
4. UH engineers to improve test for cardiovascular disease
5. UCLA researchers show how worlds smallest coffee ring may help biosensors detect disease
6. Prescription drug could boost effects of vaccines for HIV and other diseases
7. New and improved gluten-free foods developed for patients with celiac disease
8. Disease caused by insect bites can be transmitted to children at birth
9. Virginia Tech researcher explores role of human behavior in infectious disease emergence
10. New tool helps scientists see molecular signals of eye disease before symptoms arise
11. The kiss of death: Research targets lethal disease spread by insect that bites lips
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2014)... Utah , Dec. 4, 2014  Tute Genomics, ... raised $2.3 million in Series A1 funding led by ... investors also participated in the investment round. ... the healthcare community adopts next-generation sequencing and seeks new ... said Reid Robison , MD MBA, and CEO ...
(Date:12/3/2014)... , Dec. 2, 2014   Marvin Test ... innovative test solutions for military, aerospace, and manufacturing ... of its successful TS-900 PXI semiconductor test ... features of high-end systems to customers at a ... compared to traditional ATE. "Our ...
(Date:11/21/2014)... November 18, 2014 According to ... by Systems (Video, RFID, Access Control, Intrusion Detection, Parking ... Banks, Government), Component Service Geography - Global Forecasts to ... is projected to be around $25 Billion in 2014 ... growing at a CAGR of 8.69%. Browse ...
Breaking Biology News(10 mins):Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... for drinking water but about 20 years ago the once ... toxic blue-green algae which can damage the liver, intestines and ... Knoxville, will be working on an international team funded by ... resolve the ecosystem balance in the lake. Their work could ...
... This press release is available in Spanish . ... scientist has found a "green" alternative to a type ... the accumulation of heavy metals in waterways. Ornamental ... copper and zinc. But fertilizers that provide these micronutrients ...
... dietary fats are not created equal. Some types of fats have ... like those often found in plants and fish, have well documented ... destructively to some fats but not others? A new ... Biology suggests the answer may lie in how different fats ...
Cached Biology News:University of Tennessee Team receives NSF support to study toxic water in China 2A greener way to fertilize nursery crops 2The Quarterly Review of Biology: Why some fats are worse than others 2
(Date:12/19/2014)... (PRWEB) December 18, 2014 Today, ... locate its pilot production facility and future company ... and produce innovative new materials that safely and ... not only because of its historic, strong support ... efforts to attract leading edge, technology-based companies such ...
(Date:12/19/2014)... In contrast to traditional LED lights where ... Valoya uses proprietary LED technology to incorporate their spectra ... which is critical in low proximity installations. The Valoya ... its lifetime which is up to four times longer ... investment cost was clearly higher when compared to traditional ...
(Date:12/19/2014)... , Dec. 18, 2014   ISN has ... Safety Performance Indicators publication series. With data ... activity reported in 2013 within its online contractor management ... safety key performance indicator (KPI) statistics. ... U.S. publication is available in two industry ...
(Date:12/17/2014)... Houston, TX (PRWEB) December 17, 2014 ... marketing and administration for Stoller Group. In this position, ... Stoller Group, on administrative matters, develop marketing strategy and ... and services. , “Achim has tremendous knowledge and ... president of Stoller Group. “His experience and innovative thinking ...
Breaking Biology Technology:Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 2Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 3Technology Company TiFiber™ to Establish Production Facility in Fort Smith, Arkansas with Support from Local Investors 4ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Achim Noack Joins Stoller Group as Global Vice President of Marketing and Administration 2
... to innovation, American Family Insurance's Information Services Division ... The direction comes from within, and Byrne Chapman, vice president ... familiar phrase: nothing ventured, nothing gained. To build a culture ... modeled after employee-driven, quality-control programs. , ,While management experts ...
... plans to erect as many as five more buildings on ... about needs well beyond its existing base of 2,500 employees, ... administrative officer, said the company anticipates adding 1,500 more individual ... 2,500. In addition, there remains plenty of room on the ...
... protection firms could be the answer to a question you ... ,The Internet does connect you with your customers - and ... that could damage your reputation and sales. Here are several ... simple to the sophisticated, and suggestions for dealing with them. ...
Cached Biology Technology:CIO Leadership Series: Byrne Chapman, American Family Insurance 2CIO Leadership Series: Byrne Chapman, American Family Insurance 3CIO Leadership Series: Byrne Chapman, American Family Insurance 4Epic Systems will build well beyond current staff size 2Protecting your business against online brand abuse 2Protecting your business against online brand abuse 3
SDS-OutT Precipitation Reagent...
... Removal , , Removes ... cross-reactivity with other proteins , Simple, just ... Economical new surface technology, not based on ... with protein analysis. SurfactAway offers a simple ...
... speed and excellent temperature uniformity. Protocols that ... can be run without any modifications. The ... for 48 or 96 wells. In addition, ... applications are available. The High Precision Smart ...
General description: MaxiSorp TM surface is ideal for arraying molecules with mixed hydrophilic/hydrophobic domains such as proteins ID clarifier: Maxisorp(tm) with lid...
Biology Products: